ENSG00000183682


Homo sapiens

Features
Gene ID: ENSG00000183682
  
Biological name :BMP8A
  
Synonyms : BMP8A / bone morphogenetic protein 8a / Q7Z5Y6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.3
Gene start: 39491646
Gene end: 39525935
  
Corresponding Affymetrix probe sets: 207866_at (Human Genome U133 Plus 2.0 Array)   220203_at (Human Genome U133 Plus 2.0 Array)   220204_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327440
NCBI entrez gene - 353500     See in Manteia.
RefSeq - NM_181809
RefSeq Peptide - NP_861525
swissprot - Q7Z5Y6
Ensembl - ENSG00000183682
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bmp8aENSDARG00000035677Danio rerio
 ENSGALG00000038984Gallus gallus
 Bmp8aENSMUSG00000032726Mus musculus
 Bmp8bENSMUSG00000002384Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BMP8B / P34820 / bone morphogenetic protein 8bENSG0000011698598
BMP6 / P22004 / bone morphogenetic protein 6ENSG0000015316252
BMP7 / P18075 / bone morphogenetic protein 7ENSG0000010114452
BMP5 / P22003 / bone morphogenetic protein 5ENSG0000011217552
BMP2 / P12643 / bone morphogenetic protein 2ENSG0000012584531
BMP4 / P12644 / bone morphogenetic protein 4ENSG0000012537830
GDF2 / Q9UK05 / growth differentiation factor 2ENSG0000026376128
GDF6 / Q6KF10 / growth differentiation factor 6ENSG0000015646628
BMP10 / O95393 / bone morphogenetic protein 10ENSG0000016321725
GDF5 / P43026 / growth differentiation factor 5ENSG0000012596525
GDF7 / Q7Z4P5 / growth differentiation factor 7ENSG0000014386925


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IEA
 biological_processGO:0002024 diet induced thermogenesis IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0046676 negative regulation of insulin secretion IDA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0070700 BMP receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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