ENSG00000188816


Homo sapiens

Features
Gene ID: ENSG00000188816
  
Biological name :HMX2
  
Synonyms : A2RU54 / H6 family homeobox 2 / HMX2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.13
Gene start: 123148122
Gene end: 123150672
  
Corresponding Affymetrix probe sets: 244565_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000341108
NCBI entrez gene - 3167     See in Manteia.
OMIM - 600647
RefSeq - NM_005519
RefSeq - XM_005269743
RefSeq Peptide - NP_005510
swissprot - A2RU54
Ensembl - ENSG00000188816
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmx2ENSDARG00000070954Danio rerio
 HMX2ENSGALG00000030875Gallus gallus
 Hmx2ENSMUSG00000050100Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMX3 / A6NHT5 / H6 family homeobox 3ENSG0000018862041
HMX1 / Q9NP08 / H6 family homeobox 1ENSG0000021561237
NKX3-2 / P78367 / NK3 homeobox 2ENSG0000010970527
NKX2-3 / Q8TAU0 / NK2 homeobox 3ENSG0000011991922
A6NCS4 / NKX2-6 / NK2 homeobox 6ENSG0000018005322
NKX3-1 / Q99801 / NK3 homeobox 1ENSG0000016703421
NKX2-5 / P52952 / NK2 homeobox 5ENSG0000018307221
NKX2-4 / Q9H2Z4 / NK2 homeobox 4ENSG0000012581620
NKX2-8 / O15522 / NK2 homeobox 8ENSG0000013632719
NKX2-1 / P43699 / NK2 homeobox 1ENSG0000013635219
NKX2-2 / O95096 / NK2 homeobox 2ENSG0000012582018


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0048026 positive regulation of mRNA splicing, via spliceosome IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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