ENSG00000125816


Homo sapiens

Features
Gene ID: ENSG00000125816
  
Biological name :NKX2-4
  
Synonyms : NK2 homeobox 4 / NKX2-4 / Q9H2Z4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p11.22
Gene start: 21395367
Gene end: 21398028
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000345147
NCBI entrez gene - 644524     See in Manteia.
OMIM - 607808
RefSeq - NM_033176
RefSeq Peptide - NP_149416
swissprot - Q9H2Z4
Ensembl - ENSG00000125816
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkx2.1ENSDARG00000019835Danio rerio
 NKX2-4ENSGALG00000035835Gallus gallus
 Nkx2-4ENSMUSG00000054160Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKX2-1 / P43699 / NK2 homeobox 1ENSG0000013635259
NKX2-3 / Q8TAU0 / NK2 homeobox 3ENSG0000011991932
A6NCS4 / NKX2-6 / NK2 homeobox 6ENSG0000018005332
NKX2-2 / O95096 / NK2 homeobox 2ENSG0000012582030
NKX2-5 / P52952 / NK2 homeobox 5ENSG0000018307229
NKX2-8 / O15522 / NK2 homeobox 8ENSG0000013632725
NKX3-2 / P78367 / NK3 homeobox 2ENSG0000010970523
HMX3 / A6NHT5 / H6 family homeobox 3ENSG0000018862018
NKX3-1 / Q99801 / NK3 homeobox 1ENSG0000016703417
HMX1 / Q9NP08 / H6 family homeobox 1ENSG0000021561217
HMX2 / A2RU54 / H6 family homeobox 2ENSG0000018881615


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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