ENSMUSG00000054160


Mus musculus

Features
Gene ID: ENSMUSG00000054160
  
Biological name :Nkx2-4
  
Synonyms : Homeobox protein Nkx-2.4 / Nkx2-4 / Q9EQM3
  
Possible biological names infered from orthology : NK2 homeobox 4 / Q9H2Z4
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: G2
Gene start: 147083316
Gene end: 147085445
  
Corresponding Affymetrix probe sets: 10488362 (MoGene1.0st)   1432862_at (Mouse Genome 430 2.0 Array)   1432863_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066690
NCBI entrez gene - 228731     See in Manteia.
MGI - MGI:97349
RefSeq - NM_023504
RefSeq - XM_006499301
RefSeq Peptide - NP_075993
swissprot - Q9EQM3
Ensembl - ENSMUSG00000054160
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkx2.1ENSDARG00000019835Danio rerio
 NKX2-4ENSGALG00000035835Gallus gallus
 NKX2-4ENSG00000125816Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nkx2-1 / P50220 / Homeobox protein Nkx-2.1 / P43699* / NK2 homeobox 1*ENSMUSG0000000149660
Nkx2-3 / P97334 / Homeobox protein Nkx-2.3 / Q8TAU0* / NK2 homeobox 3*ENSMUSG0000004422031
Nkx2-2 / P42586 / NK2 homeobox 2 / O95096*ENSMUSG0000002743429
Nkx2-5 / P42582 / Homeobox protein Nkx-2.5 / P52952* / NK2 homeobox 5*ENSMUSG0000001557928
Nkx2-6 / P43688 / Homeobox protein Nkx-2.6 / A6NCS4* / NK2 homeobox 6*ENSMUSG0000004418628
Nkx2-9 / O70584 / Homeobox protein Nkx-2.8 / NKX2-8* / O15522* / NK2 homeobox 8*ENSMUSG0000005866925
Nkx3-2 / P97503 / Homeobox protein Nkx-3.2 / P78367* / NK3 homeobox 2*ENSMUSG0000004969123
Hmx1 / O70218 / Homeobox protein HMX1 / Q9NP08* / H6 family homeobox 1*ENSMUSG0000006743818
Hmx3 / P42581 / Homeobox protein HMX3 / A6NHT5* / H6 family homeobox 3*ENSMUSG0000004014817
Nkx3-1 / P97436 / NK3 homeobox 1 / Q99801*ENSMUSG0000002206117
Hmx2 / P43687 / Homeobox protein HMX2 / A2RU54* / H6 family homeobox 2*ENSMUSG0000005010015


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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