ENSDARG00000019835


Danio rerio

Features
Gene ID: ENSDARG00000019835
  
Biological name :nkx2.1
  
Synonyms : NK2 homeobox 1 / nkx2.1
  
Possible biological names infered from orthology : Homeobox protein Nkx-2.1 / Homeobox protein Nkx-2.4 / NK2 homeobox 4 / NKX2-4 / P43699 / P50220 / Q9EQM3 / Q9H2Z4
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 38262408
Gene end: 38264625
  
Corresponding Affymetrix probe sets: Dr.2198.1.S1_at (Zebrafish Array)   NM_131776_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000025546
NCBI entrez gene - 81883     See in Manteia.
RefSeq - NM_131776
RefSeq Peptide - NP_571851
swissprot - B3DH68
ZFIN ID - ZDB-GENE-010404-1
Ensembl - ENSDARG00000019835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NKX2-1ENSGALG00000037632Gallus gallus
 NKX2-1ENSG00000136352Homo sapiens
 NKX2-4ENSG00000125816Homo sapiens
 Nkx2-1ENSMUSG00000001496Mus musculus
 Nkx2-4ENSMUSG00000054160Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nkx2.4a / NK2 homeobox 4aENSDARG0000007510766
nkx2.4b / NK2 homeobox 4bENSDARG0000010410757
Q90481 / nkx2.2a / NK2 homeobox 2a / NKX2-2* / O95096* / NK2 homeobox 2*ENSDARG0000005329829
nkx2.3 / NK2 homeobox 3 / Q8TAU0* / P42582* / P43688* / P52952* / P97334* / A6NCS4* / NKX2-5* / NKX2-6* / NK2 homeobox 5* / NK2 homeobox 6* / Homeobox protein Nkx-2.6 * / Homeobox protein N...ENSDARG0000003909529
nkx2.5 / NK2 homeobox 5 / Q8TAU0* / P42582* / P43688* / P52952* / P97334* / A6NCS4* / NKX2-3* / NKX2-6* / NK2 homeobox 3* / NK2 homeobox 6* / Homeobox protein Nkx-2.6 * / Homeobox protein N...ENSDARG0000001800427
nkx2.7 / NK2 transcription factor related 7 / Q8TAU0* / NKX2-6* / P42582* / P43688* / P52952* / P97334* / A6NCS4* / NKX2-3* / NKX2-5* / NK2 homeobox 3* / NK2 homeobox 5* / NK2 homeobox 6* /...ENSDARG0000002123225
nkx2.2b / NK2 homeobox 2bENSDARG0000010154923
nkx3.2 / NK3 homeobox 2 / P78367*ENSDARG0000003763919
nkx3.3 / NK3 homeobox 3ENSDARG0000006932717
hmx3b / H6 family homeobox 3bENSDARG0000009671615
nkx3-1 / NK3 homeobox 1 / P97436* / Q99801*ENSDARG0000007828015
hmx3a / H6 family homeobox 3a / HMX3* / P42581* / A6NHT5* / H6 family homeobox 3* / Homeobox protein HMX3 *ENSDARG0000007095515
hmx1 / H6 family homeobox 1 / O70218* / Q9NP08* / Homeobox protein HMX1 *ENSDARG0000009565114
hmx2 / H6 family homeobox 2 / A2RU54* / P43687* / Homeobox protein HMX2 *ENSDARG0000007095413
hmx4 / H6 family homeobox 4ENSDARG0000000794112


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0021536 diencephalon development IMP
 biological_processGO:0021854 hypothalamus development IGI
 biological_processGO:0030900 forebrain development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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