ENSGALG00000001093


Gallus gallus

Features
Gene ID: ENSGALG00000001093
  
Biological name :TCF3
  
Synonyms : TCF3 / transcription factor 3
  
Possible biological names infered from orthology : P15806 / P15923 / Transcription factor E2-alpha
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 2386330
Gene end: 2441061
  
Corresponding Affymetrix probe sets: Gga.4979.1.S1_at (Chicken Array)   Gga.4979.2.S1_at (Chicken Array)   GgaAffx.12023.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000040388
Ensembl peptide - ENSGALP00000054816
Ensembl peptide - ENSGALP00000048808
Ensembl peptide - ENSGALP00000001635
NCBI entrez gene - 395146     See in Manteia.
RefSeq - XM_015299914
RefSeq - XM_015299909
RefSeq - XM_015299910
RefSeq - XM_015299911
RefSeq - XM_015299912
RefSeq - XM_015299913
RefSeq - NM_204486
RefSeq - XM_015299889
RefSeq - XM_015299890
RefSeq - XM_015299891
RefSeq - XM_015299892
RefSeq - XM_015299894
RefSeq - XM_015299895
RefSeq - XM_015299896
RefSeq - XM_015299897
RefSeq - XM_015299898
RefSeq - XM_015299899
RefSeq - XM_015299900
RefSeq - XM_015299901
RefSeq - XM_015299902
RefSeq - XM_015299903
RefSeq - XM_015299905
RefSeq - XM_015299906
RefSeq - XM_015299907
RefSeq - XM_015299908
RefSeq Peptide - NP_989817
swissprot - A0A1D6UPQ1
swissprot - A0A1D5PPL4
swissprot - A0A1D5P7W4
swissprot - Q70IK3
Ensembl - ENSGALG00000001093
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tcf3aENSDARG00000005915Danio rerio
 tcf3bENSDARG00000099999Danio rerio
 TCF3ENSG00000071564Homo sapiens
 Tcf3ENSMUSG00000020167Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TCF12 / transcription factor 12 / Q61286* / Q99081*ENSGALG0000000430441
TCF4* / P15884* / Q60722* / transcription factor 4*ENSGALG0000003377014


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0033152 immunoglobulin V(D)J recombination IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0031435 mitogen-activated protein kinase kinase kinase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043425 bHLH transcription factor binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0070491 repressing transcription factor binding IEA
 molecular_functionGO:0070644 vitamin D response element binding IEA
 molecular_functionGO:0070888 E-box binding IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis
RUNX1 regulates transcription of genes involved in differentiation of HSCs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000014645 MEF2C / myocyte enhancer factor 2C / Q06413* / Q8CFN5* / Mus musculus myocyte enhancer factor 2C (Mef2c), transcript variant 14, mRNA.*  / reaction / complex
 ENSGALG00000000172 MYOG / P17920 / Myogenin / P12979* / P15173*  / complex
 ENSGALG00000032366 MEF2A / myocyte enhancer factor 2A / Q02078* / Q60929* / Mus musculus myocyte enhancer factor 2A (Mef2a), transcript variant 7, mRNA.*  / reaction / complex
 ENSGALG00000010936 MYF6 / myogenic factor 6 / P15375* / P23409*  / complex






 

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