ENSGALG00000002403


Gallus gallus

Features
Gene ID: ENSGALG00000002403
  
Biological name :ULK1
  
Synonyms : ULK1 / unc-51 like autophagy activating kinase 1
  
Possible biological names infered from orthology : O75385 / unc-51 like kinase 1
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 2638997
Gene end: 2708090
  
Corresponding Affymetrix probe sets: Gga.14302.1.S1_s_at (Chicken Array)   GgaAffx.25476.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003776
Ensembl peptide - ENSGALP00000058317
Ensembl peptide - ENSGALP00000052115
NCBI entrez gene - 416800     See in Manteia.
RefSeq - XM_015275647
RefSeq - XM_015275648
RefSeq - XM_415091
swissprot - A0A1D5PZA7
swissprot - A0A1D5PH38
swissprot - F1NZ50
Ensembl - ENSGALG00000002403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ulk1aENSDARG00000062518Danio rerio
 ulk1bENSDARG00000074481Danio rerio
 ULK1ENSG00000177169Homo sapiens
 Ulk1ENSMUSG00000029512Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ULK2 / unc-51 like autophagy activating kinase 2 / Q8IYT8* / Q9QY01* / unc-51 like kinase 2*ENSGALG0000000472751
ULK3 / unc-51 like kinase 3 / Q3U3Q1* / Q6PHR2*ENSGALG0000003221514
CHUK / inhibitor of nuclear factor kappa-B kinase subunit alpha / O15111* / conserved helix-loop-helix ubiquitous kinase*ENSGALG0000000328912
IKBKE / inhibitor of nuclear factor kappa B kinase subunit epsilon / Q14164* / Q9R0T8*ENSGALG0000001335611
TBK1 / TANK binding kinase 1 / Q9UHD2* / Q9WUN2*ENSGALG0000000984011
IKBKB / inhibitor of nuclear factor kappa B kinase subunit beta / O14920* / inhibitor of kappaB kinase beta*ENSGALG0000003183210


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR022708  Serine/threonine-protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0016236 macroautophagy IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0031333 negative regulation of protein complex assembly IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0048675 axon extension IBA
 biological_processGO:0075044 autophagy of host cells involved in interaction with symbiont IEA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032045 guanyl-nucleotide exchange factor complex IEA
 cellular_componentGO:0034045 phagophore assembly site membrane IEA
 cellular_componentGO:0097629 extrinsic component of omegasome membrane IEA
 cellular_componentGO:0097632 extrinsic component of phagophore assembly site membrane IEA
 cellular_componentGO:0097635 extrinsic component of autophagosome membrane IEA
 cellular_componentGO:1990316 Atg1/ULK1 kinase complex IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051020 GTPase binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
TBC/RABGAPs
RAB GEFs exchange GTP for GDP on RABs
Receptor Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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