ENSGALG00000032215


Gallus gallus

Features
Gene ID: ENSGALG00000032215
  
Biological name :ULK3
  
Synonyms : ULK3 / unc-51 like kinase 3
  
Possible biological names infered from orthology : Q3U3Q1 / Q6PHR2
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 2344374
Gene end: 2349530
  
Corresponding Affymetrix probe sets: GgaAffx.12561.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056456
NCBI entrez gene - 769780     See in Manteia.
RefSeq - NM_001162907
RefSeq - XM_004943691
RefSeq - XM_015278896
RefSeq Peptide - NP_001156379
swissprot - A0A1D5PU54
Ensembl - ENSGALG00000032215
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ulk3ENSDARG00000101661Danio rerio
 ULK3ENSG00000140474Homo sapiens
 Ulk3ENSMUSG00000032308Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ULK1 / unc-51 like autophagy activating kinase 1 / O75385* / unc-51 like kinase 1*ENSGALG0000000240334
ULK2 / unc-51 like autophagy activating kinase 2 / Q8IYT8* / Q9QY01* / unc-51 like kinase 2*ENSGALG0000000472731
TBK1 / TANK binding kinase 1 / Q9UHD2* / Q9WUN2*ENSGALG0000000984018
CHUK / inhibitor of nuclear factor kappa-B kinase subunit alpha / O15111* / conserved helix-loop-helix ubiquitous kinase*ENSGALG0000000328918
IKBKE / inhibitor of nuclear factor kappa B kinase subunit epsilon / Q14164* / Q9R0T8*ENSGALG0000001335616
IKBKB / inhibitor of nuclear factor kappa B kinase subunit beta / O14920* / inhibitor of kappaB kinase beta*ENSGALG0000003183213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR007330  MIT
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IEA
 biological_processGO:0045880 positive regulation of smoothened signaling pathway IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008096 SUFU / SUFU negative regulator of hedgehog signaling / Q9UMX1* / Q9Z0P7*  / complex
 ENSGALG00000040266 GLI3 / GLI family zinc finger 3 / P10071* / Q61602* / Transcriptional activator GLI3 Transcriptional repressor GLI3R*  / reaction
 ENSGALG00000011630 GLI2 / GLI family zinc finger 2 / P10070* / Q0VGT2* / Zinc finger protein GLI2 *  / reaction






 

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