ENSGALG00000004048


Gallus gallus

Features
Gene ID: ENSGALG00000004048
  
Biological name :PTPRS
  
Synonyms : F1NWE3 / PTPRS / Receptor-type tyrosine-protein phosphatase S
  
Possible biological names infered from orthology : B0V2N1 / protein tyrosine phosphatase, receptor type S / Q13332
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 4626074
Gene end: 4748768
  
Corresponding Affymetrix probe sets: Gga.18499.1.A1_at (Chicken Array)   Gga.18499.1.S1_at (Chicken Array)   Gga.2657.1.S1_s_at (Chicken Array)   Gga.2675.1.S1_at (Chicken Array)   Gga.783.1.A1_at (Chicken Array)   Gga.783.1.S1_at (Chicken Array)   Gga.784.1.S1_at (Chicken Array)   Gga.784.1.S1_s_at (Chicken Array)   Gga.809.1.A1_at (Chicken Array)   GgaAffx.20371.1.S1_s_at (Chicken Array)   GgaAffx.21685.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056093
Ensembl peptide - ENSGALP00000006433
Ensembl peptide - ENSGALP00000057158
Ensembl peptide - ENSGALP00000044197
Ensembl peptide - ENSGALP00000055049
Ensembl peptide - ENSGALP00000054704
NCBI entrez gene - 396375     See in Manteia.
RefSeq - XM_015300040
RefSeq - XM_015300033
RefSeq - XM_015300034
RefSeq - XM_015300035
RefSeq - XM_015300036
RefSeq - XM_015300037
RefSeq - XM_015300038
RefSeq - XM_015300039
RefSeq - NM_205407
RefSeq - XM_015300027
RefSeq - XM_015300028
RefSeq - XM_015300029
RefSeq - XM_015300030
RefSeq - XM_015300031
RefSeq - XM_015300032
RefSeq Peptide - NP_990738
swissprot - A0A1D5PT51
swissprot - A0A1D5PQ87
swissprot - A0A1D5PW29
swissprot - F1NWE3
swissprot - A0A1D5NV24
swissprot - A0A1D5PPA5
Ensembl - ENSGALG00000004048
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprsaENSDARG00000059738Danio rerio
 ptprsaENSDARG00000110940Danio rerio
 PTPRSENSG00000105426Homo sapiens
 PtprsENSMUSG00000013236Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRD / protein tyrosine phosphatase, receptor type D / P23468* / Q64487*ENSGALG0000001505873
PTPRF / protein tyrosine phosphatase, receptor type F / A2A8L5* / P10586* / Receptor-type tyrosine-protein phosphatase F *ENSGALG0000001005367
PTPRZ1 / protein tyrosine phosphatase, receptor type Z1 / B9EKR1* / P23471* / protein tyrosine phosphatase, receptor type Z, polypeptide 1*ENSGALG0000004011421
PTPRM / protein tyrosine phosphatase, receptor type M / P28827* / P28828*ENSGALG0000003128421
PTPRK / protein tyrosine phosphatase, receptor type K / P35822* / Q15262*ENSGALG0000003742320
PTPRT / protein tyrosine phosphatase, receptor type T / O14522* / Q99M80* / Receptor-type tyrosine-protein phosphatase T *ENSGALG0000003788920
PTPRU / receptor-type tyrosine-protein phosphatase U precursor / B1AUH1* / Q92729* / protein tyrosine phosphatase, receptor type U*ENSGALG0000003144019
PTPRG / receptor-type tyrosine-protein phosphatase gamma precursor / P23470* / protein tyrosine phosphatase, receptor type G* / receptor-type tyrosine-protein phosphatase gamma isoform 2 *ENSGALG0000000717718
PTPRA / protein tyrosine phosphatase, receptor type A / P18052* / P18433*ENSGALG0000001599517
PTPRE / protein tyrosine phosphatase, receptor type E / P23469* / P49446* / Receptor-type tyrosine-protein phosphatase epsilon *ENSGALG0000000982316
PTPRC / protein tyrosine phosphatase, receptor type CENSGALG0000000219216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0022038 corpus callosum development IEA
 biological_processGO:0030517 negative regulation of axon extension ISS
 biological_processGO:0032687 negative regulation of interferon-alpha production IEA
 biological_processGO:0032688 negative regulation of interferon-beta production IEA
 biological_processGO:0034164 negative regulation of toll-like receptor 9 signaling pathway IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0048671 negative regulation of collateral sprouting ISS
 biological_processGO:0048681 negative regulation of axon regeneration ISS
 biological_processGO:0061000 negative regulation of dendritic spine development ISS
 biological_processGO:0090557 establishment of endothelial intestinal barrier IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane ISS
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0099061 integral component of postsynaptic density membrane ISS
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0035374 chondroitin sulfate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0043395 heparan sulfate proteoglycan binding IDA


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000217 PPFIA4 / PTPRF interacting protein alpha 4 / O75335* / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4*  / reaction / complex
 ENSGALG00000040241 NTRK3 / Q91044 / NT-3 growth factor receptor / Q16288* / Q6VNS1* / neurotrophic receptor tyrosine kinase 3*  / complex / reaction






 

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