ENSGALG00000037423


Gallus gallus

Features
Gene ID: ENSGALG00000037423
  
Biological name :PTPRK
  
Synonyms : protein tyrosine phosphatase, receptor type K / PTPRK
  
Possible biological names infered from orthology : P35822 / Q15262
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 58821365
Gene end: 59132416
  
Corresponding Affymetrix probe sets: Gga.16194.1.S1_at (Chicken Array)   GgaAffx.9387.1.S1_at (Chicken Array)   GgaAffx.9387.1.S1_s_at (Chicken Array)   GgaAffx.9415.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053789
NCBI entrez gene - 421711     See in Manteia.
RefSeq - XM_015284454
RefSeq - XM_015284455
RefSeq - XM_015284456
RefSeq - XM_015284457
RefSeq - XM_015284453
swissprot - A0A1D5PLR9
Ensembl - ENSGALG00000037423
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprkENSDARG00000063416Danio rerio
 PTPRKENSG00000152894Homo sapiens
 PtprkENSMUSG00000019889Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRM / protein tyrosine phosphatase, receptor type M / P28827* / P28828*ENSGALG0000003128464
PTPRU / receptor-type tyrosine-protein phosphatase U precursor / B1AUH1* / Q92729* / protein tyrosine phosphatase, receptor type U*ENSGALG0000003144062
PTPRT / protein tyrosine phosphatase, receptor type T / O14522* / Q99M80* / Receptor-type tyrosine-protein phosphatase T *ENSGALG0000003788961
PTPRD / protein tyrosine phosphatase, receptor type D / P23468* / Q64487*ENSGALG0000001505829
PTPRF / protein tyrosine phosphatase, receptor type F / A2A8L5* / P10586* / Receptor-type tyrosine-protein phosphatase F *ENSGALG0000001005328
PTPRS / F1NWE3 / Receptor-type tyrosine-protein phosphatase S / B0V2N1* / Q13332* / protein tyrosine phosphatase, receptor type S*ENSGALG0000000404828
PTPRZ1 / protein tyrosine phosphatase, receptor type Z1 / B9EKR1* / P23471* / protein tyrosine phosphatase, receptor type Z, polypeptide 1*ENSGALG0000004011422
PTPRG / receptor-type tyrosine-protein phosphatase gamma precursor / P23470* / protein tyrosine phosphatase, receptor type G* / receptor-type tyrosine-protein phosphatase gamma isoform 2 *ENSGALG0000000717721
PTPRC / protein tyrosine phosphatase, receptor type CENSGALG0000000219219
PTPRA / protein tyrosine phosphatase, receptor type A / P18052* / P18433*ENSGALG0000001599518
PTPRE / protein tyrosine phosphatase, receptor type E / P23469* / P49446* / Receptor-type tyrosine-protein phosphatase epsilon *ENSGALG0000000982318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR000998  MAM domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010839 negative regulation of keratinocyte proliferation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0034394 protein localization to cell surface IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0045786 negative regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048041 focal adhesion assembly IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031256 leading edge membrane IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0045295 gamma-catenin binding IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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