ENSGALG00000015995


Gallus gallus

Features
Gene ID: ENSGALG00000015995
  
Biological name :PTPRA
  
Synonyms : protein tyrosine phosphatase, receptor type A / PTPRA
  
Possible biological names infered from orthology : P18052 / P18433
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 89114207
Gene end: 89212205
  
Corresponding Affymetrix probe sets: Gga.3505.1.S1_at (Chicken Array)   Gga.4972.1.S1_at (Chicken Array)   Gga.4972.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015955
Ensembl peptide - ENSGALP00000061337
Ensembl peptide - ENSGALP00000059426
NCBI entrez gene - 396060     See in Manteia.
RefSeq - NM_205154
RefSeq - XM_015286026
RefSeq Peptide - NP_990485
swissprot - A0A1L1RRB0
swissprot - A0A1L1RKZ6
swissprot - F1NPE8
Ensembl - ENSGALG00000015995
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptpraENSDARG00000001769Danio rerio
 PTPRAENSG00000132670Homo sapiens
 PtpraENSMUSG00000027303Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRE / protein tyrosine phosphatase, receptor type E / P23469* / P49446* / Receptor-type tyrosine-protein phosphatase epsilon *ENSGALG0000000982358
PTPRD / protein tyrosine phosphatase, receptor type D / P23468* / Q64487*ENSGALG0000001505842
PTPRF / protein tyrosine phosphatase, receptor type F / A2A8L5* / P10586* / Receptor-type tyrosine-protein phosphatase F *ENSGALG0000001005342
PTPRS / F1NWE3 / Receptor-type tyrosine-protein phosphatase S / B0V2N1* / Q13332* / protein tyrosine phosphatase, receptor type S*ENSGALG0000000404841
PTPRC / protein tyrosine phosphatase, receptor type CENSGALG0000000219234
PTPRT / protein tyrosine phosphatase, receptor type T / O14522* / Q99M80* / Receptor-type tyrosine-protein phosphatase T *ENSGALG0000003788931
PTPRM / protein tyrosine phosphatase, receptor type M / P28827* / P28828*ENSGALG0000003128431
PTPRK / protein tyrosine phosphatase, receptor type K / P35822* / Q15262*ENSGALG0000003742331
PTPRZ1 / protein tyrosine phosphatase, receptor type Z1 / B9EKR1* / P23471* / protein tyrosine phosphatase, receptor type Z, polypeptide 1*ENSGALG0000004011430
PTPRG / receptor-type tyrosine-protein phosphatase gamma precursor / P23470* / protein tyrosine phosphatase, receptor type G* / receptor-type tyrosine-protein phosphatase gamma isoform 2 *ENSGALG0000000717728
PTPRU / receptor-type tyrosine-protein phosphatase U precursor / B1AUH1* / Q92729* / protein tyrosine phosphatase, receptor type U*ENSGALG0000003144028


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR016336  Receptor tyrosine-protein phosphatase, alpha/epsilon-type
 IPR027262  Receptor tyrosine-protein phosphatase alpha
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
NCAM signaling for neurite out-growth
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / reaction / complex
 ENSGALG00000031741 PTK2 / Q00944 / Focal adhesion kinase 1 / P34152* / Q05397* / protein tyrosine kinase 2* / PTK2 protein tyrosine kinase 2*  / complex
 ENSGALG00000039450 SOS1 / SOS Ras/Rac guanine nucleotide exchange factor 1 / Q07889* / Q62245* / Son of sevenless homolog 1 *  / reaction / complex
 ENSGALG00000015022 FYN / tyrosine-protein kinase Fyn / P06241* / P39688* / FYN proto-oncogene, Src family tyrosine kinase*  / complex






 

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