ENSMUSG00000019889


Mus musculus

Features
Gene ID: ENSMUSG00000019889
  
Biological name :Ptprk
  
Synonyms : P35822 / protein tyrosine phosphatase, receptor type, K / Ptprk
  
Possible biological names infered from orthology : Q15262
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: A4
Gene start: 28074820
Gene end: 28597397
  
Corresponding Affymetrix probe sets: 10362314 (MoGene1.0st)   1423277_at (Mouse Genome 430 2.0 Array)   1423278_at (Mouse Genome 430 2.0 Array)   1431680_a_at (Mouse Genome 430 2.0 Array)   1441276_at (Mouse Genome 430 2.0 Array)   1441277_s_at (Mouse Genome 430 2.0 Array)   1443699_at (Mouse Genome 430 2.0 Array)   1444763_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151986
Ensembl peptide - ENSMUSP00000126279
Ensembl peptide - ENSMUSP00000151294
Ensembl peptide - ENSMUSP00000151493
Ensembl peptide - ENSMUSP00000151866
NCBI entrez gene - 19272     See in Manteia.
MGI - MGI:103310
RefSeq - XM_017313850
RefSeq - XM_006512613
RefSeq - XM_006512614
RefSeq - XM_006512615
RefSeq - XM_006512617
RefSeq - XM_006512620
RefSeq - XM_011243143
RefSeq - XM_011243144
RefSeq - XM_011243146
RefSeq - NM_008983
RefSeq - XM_006512606
RefSeq - XM_006512607
RefSeq - XM_006512608
RefSeq - XM_006512609
RefSeq - XM_006512610
RefSeq - XM_006512611
RefSeq - XM_006512612
RefSeq Peptide - NP_001346285
RefSeq Peptide - NP_033009
RefSeq Peptide - NP_001346284
swissprot - A0A1W2P6K2
swissprot - B2RRF0
swissprot - P35822
swissprot - A0A1W2P7Y1
swissprot - A0A1W2P706
Ensembl - ENSMUSG00000019889
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprkENSDARG00000063416Danio rerio
 PTPRKENSGALG00000037423Gallus gallus
 PTPRKENSG00000152894Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ptprm / P28828 / protein tyrosine phosphatase, receptor type, M / P28827*ENSMUSG0000003327861
Ptpru / B1AUH1 / protein tyrosine phosphatase, receptor type, U / Q92729*ENSMUSG0000002890959
Ptprt / Q99M80 / Receptor-type tyrosine-protein phosphatase T / O14522* / protein tyrosine phosphatase, receptor type T*ENSMUSG0000005314157
Ptprf / A2A8L5 / Receptor-type tyrosine-protein phosphatase F / P10586* / protein tyrosine phosphatase, receptor type F*ENSMUSG0000003329527
Ptprs / B0V2N1 / Receptor-type tyrosine-protein phosphatase S / Q13332* / protein tyrosine phosphatase, receptor type S*ENSMUSG0000001323627
Ptprd / Q64487 / protein tyrosine phosphatase, receptor type, D / P23468*ENSMUSG0000002839926
B9EKR1 / Ptprz1 / protein tyrosine phosphatase, receptor type Z, polypeptide 1 / P23471* / protein tyrosine phosphatase, receptor type Z1*ENSMUSG0000006874821
Ptprc / protein tyrosine phosphatase, receptor type, CENSMUSG0000002639520
Ptprg / receptor-type tyrosine-protein phosphatase gamma isoform 2 / P23470* / protein tyrosine phosphatase, receptor type G*ENSMUSG0000002174519
Ptpra / P18052 / protein tyrosine phosphatase, receptor type, A / P18433*ENSMUSG0000002730318
Ptpre / P49446 / Receptor-type tyrosine-protein phosphatase epsilon / P23469* / protein tyrosine phosphatase, receptor type E*ENSMUSG0000004183617


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR000998  MAM domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010839 negative regulation of keratinocyte proliferation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0034394 protein localization to cell surface IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0034644 cellular response to UV IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0045786 negative regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048041 focal adhesion assembly IEA
 cellular_componentGO:0001750 photoreceptor outer segment IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IDA
 cellular_componentGO:0030425 dendrite IDA
 cellular_componentGO:0031256 leading edge membrane IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0045295 gamma-catenin binding IEA


Pathways (from Reactome)
Pathway description
EGFR downregulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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