ENSMUSG00000033278


Mus musculus

Features
Gene ID: ENSMUSG00000033278
  
Biological name :Ptprm
  
Synonyms : P28828 / protein tyrosine phosphatase, receptor type, M / Ptprm
  
Possible biological names infered from orthology : P28827
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E1.1
Gene start: 66666947
Gene end: 67354457
  
Corresponding Affymetrix probe sets: 10452571 (MoGene1.0st)   1422541_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000153662
Ensembl peptide - ENSMUSP00000153042
Ensembl peptide - ENSMUSP00000153179
Ensembl peptide - ENSMUSP00000153463
Ensembl peptide - ENSMUSP00000045603
NCBI entrez gene - 19274     See in Manteia.
MGI - MGI:102694
RefSeq - XM_017317348
RefSeq - XM_006523871
RefSeq - XM_006523872
RefSeq - XM_006523873
RefSeq - XM_011246324
RefSeq - XM_017317345
RefSeq - XM_017317346
RefSeq - XM_017317347
RefSeq - NM_001357625
RefSeq - NM_008984
RefSeq - XM_006523864
RefSeq - XM_006523865
RefSeq - XM_006523866
RefSeq - XM_006523867
RefSeq - XM_006523868
RefSeq - XM_006523869
RefSeq - XM_006523870
RefSeq Peptide - NP_033010
RefSeq Peptide - NP_001344554
swissprot - Q68FM4
swissprot - A0A286YDL1
swissprot - P28828
swissprot - A0A286YCL1
swissprot - A0A286YCW9
Ensembl - ENSMUSG00000033278
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01084131.1ENSDARG00000114762Danio rerio
 si:ch1073-391i24.1ENSDARG00000089172Danio rerio
 PTPRMENSGALG00000031284Gallus gallus
 PTPRMENSG00000173482Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ptprt / Q99M80 / Receptor-type tyrosine-protein phosphatase T / O14522* / protein tyrosine phosphatase, receptor type T*ENSMUSG0000005314165
Ptprk / P35822 / protein tyrosine phosphatase, receptor type, K / Q15262*ENSMUSG0000001988961
Ptpru / B1AUH1 / protein tyrosine phosphatase, receptor type, U / Q92729*ENSMUSG0000002890953
Ptprf / A2A8L5 / Receptor-type tyrosine-protein phosphatase F / P10586* / protein tyrosine phosphatase, receptor type F*ENSMUSG0000003329528
Ptprs / B0V2N1 / Receptor-type tyrosine-protein phosphatase S / Q13332* / protein tyrosine phosphatase, receptor type S*ENSMUSG0000001323627
Ptprd / Q64487 / protein tyrosine phosphatase, receptor type, D / P23468*ENSMUSG0000002839926
B9EKR1 / Ptprz1 / protein tyrosine phosphatase, receptor type Z, polypeptide 1 / P23471* / protein tyrosine phosphatase, receptor type Z1*ENSMUSG0000006874822
Ptprg / receptor-type tyrosine-protein phosphatase gamma isoform 2 / P23470* / protein tyrosine phosphatase, receptor type G*ENSMUSG0000002174519
Ptprc / protein tyrosine phosphatase, receptor type, CENSMUSG0000002639519
Ptpra / P18052 / protein tyrosine phosphatase, receptor type, A / P18433*ENSMUSG0000002730318
Ptpre / P49446 / Receptor-type tyrosine-protein phosphatase epsilon / P23469* / protein tyrosine phosphatase, receptor type E*ENSMUSG0000004183617


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR000998  MAM domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013151  Immunoglobulin
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR021157  Cytochrome c1, transmembrane anchor, C-terminal
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001937 negative regulation of endothelial cell proliferation IEA
 biological_processGO:0006470 protein dephosphorylation ISS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010596 negative regulation of endothelial cell migration IEA
 biological_processGO:0010842 retina layer formation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0031290 retinal ganglion cell axon guidance IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0097755 positive regulation of blood vessel diameter IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity ISO
 molecular_functionGO:0005001 transmembrane receptor protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005591 decreased vasodilation "less than the expected or normal widening of the lumen of the blood vessels" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Birc6tm1Nai/Birc6tm1Nai
Genetic Background: involves: 129S4/SvJae * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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