ENSMUSG00000013236


Mus musculus

Features
Gene ID: ENSMUSG00000013236
  
Biological name :Ptprs
  
Synonyms : B0V2N1 / Ptprs / Receptor-type tyrosine-protein phosphatase S
  
Possible biological names infered from orthology : protein tyrosine phosphatase, receptor type S / Q13332
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: D
Gene start: 56412426
Gene end: 56476483
  
Corresponding Affymetrix probe sets: 10452047 (MoGene1.0st)   1426794_at (Mouse Genome 430 2.0 Array)   1426795_at (Mouse Genome 430 2.0 Array)   1427688_a_at (Mouse Genome 430 2.0 Array)   1436855_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000153134
Ensembl peptide - ENSMUSP00000084038
Ensembl peptide - ENSMUSP00000153335
Ensembl peptide - ENSMUSP00000153612
Ensembl peptide - ENSMUSP00000153533
Ensembl peptide - ENSMUSP00000153398
Ensembl peptide - ENSMUSP00000064048
NCBI entrez gene - 19280     See in Manteia.
MGI - MGI:97815
RefSeq - XM_017317350
RefSeq - XM_006523878
RefSeq - XM_006523879
RefSeq - XM_006523880
RefSeq - XM_006523881
RefSeq - XM_006523882
RefSeq - XM_006523883
RefSeq - XM_006523884
RefSeq - XM_006523886
RefSeq - XM_017317349
RefSeq - NM_001252453
RefSeq - NM_001252455
RefSeq - NM_001252456
RefSeq - NM_011218
RefSeq - XM_006523874
RefSeq - XM_006523875
RefSeq - XM_006523876
RefSeq - XM_006523877
RefSeq Peptide - NP_001239382
RefSeq Peptide - NP_001239384
RefSeq Peptide - NP_001239385
RefSeq Peptide - NP_035348
swissprot - B0V2N1
swissprot - A0A286YDF6
swissprot - A0A286YEA4
swissprot - A0A286YDS2
swissprot - A0A286YDQ1
Ensembl - ENSMUSG00000013236
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprsaENSDARG00000059738Danio rerio
 ptprsaENSDARG00000110940Danio rerio
 PTPRSENSGALG00000004048Gallus gallus
 PTPRSENSG00000105426Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ptprf / A2A8L5 / Receptor-type tyrosine-protein phosphatase F / P10586* / protein tyrosine phosphatase, receptor type F*ENSMUSG0000003329566
Ptprd / Q64487 / protein tyrosine phosphatase, receptor type, D / P23468*ENSMUSG0000002839959
B9EKR1 / Ptprz1 / protein tyrosine phosphatase, receptor type Z, polypeptide 1 / P23471* / protein tyrosine phosphatase, receptor type Z1*ENSMUSG0000006874822
Ptprk / P35822 / protein tyrosine phosphatase, receptor type, K / Q15262*ENSMUSG0000001988921
Ptprm / P28828 / protein tyrosine phosphatase, receptor type, M / P28827*ENSMUSG0000003327821
Ptprt / Q99M80 / Receptor-type tyrosine-protein phosphatase T / O14522* / protein tyrosine phosphatase, receptor type T*ENSMUSG0000005314120
Ptpru / B1AUH1 / protein tyrosine phosphatase, receptor type, U / Q92729*ENSMUSG0000002890919
Ptpra / P18052 / protein tyrosine phosphatase, receptor type, A / P18433*ENSMUSG0000002730318
Ptprc / protein tyrosine phosphatase, receptor type, CENSMUSG0000002639518
Ptprg / receptor-type tyrosine-protein phosphatase gamma isoform 2 / P23470* / protein tyrosine phosphatase, receptor type G*ENSMUSG0000002174518
Ptpre / P49446 / Receptor-type tyrosine-protein phosphatase epsilon / P23469* / protein tyrosine phosphatase, receptor type E*ENSMUSG0000004183616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation ISO
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0010977 negative regulation of neuron projection development IMP
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0021510 spinal cord development IMP
 biological_processGO:0021549 cerebellum development IMP
 biological_processGO:0021766 hippocampus development IMP
 biological_processGO:0021987 cerebral cortex development IMP
 biological_processGO:0022038 corpus callosum development IMP
 biological_processGO:0030517 negative regulation of axon extension IMP
 biological_processGO:0032687 negative regulation of interferon-alpha production IEA
 biological_processGO:0032688 negative regulation of interferon-beta production IEA
 biological_processGO:0034164 negative regulation of toll-like receptor 9 signaling pathway IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IMP
 biological_processGO:0048671 negative regulation of collateral sprouting IMP
 biological_processGO:0048681 negative regulation of axon regeneration IMP
 biological_processGO:0061000 negative regulation of dendritic spine development IMP
 biological_processGO:0090557 establishment of endothelial intestinal barrier IMP
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030285 integral component of synaptic vesicle membrane ISS
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0099061 integral component of postsynaptic density membrane ISS
 molecular_functionGO:0004721 phosphoprotein phosphatase activity ISO
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0035374 chondroitin sulfate binding IDA
 molecular_functionGO:0043395 heparan sulfate proteoglycan binding ISS


Pathways (from Reactome)
Pathway description
Receptor-type tyrosine-protein phosphatases
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000071 axial skeleton hypoplasia "reduced cell number in the skeletal elements of the trunk" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:55583]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0000382 underdeveloped hair follicles "arrest of or retarded differentiation of the epidermal invaginations from which the hair shaft develops" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0000534 abnormal ureter morphology "anomalous structure of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0000536 hydroureter "distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0000761 thin diaphragm muscle "reduced thickness of the diaphragm muscle" [MGI:CLS, J:60159]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0000937 abnormal motor neuron morphology "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0000939 reduced motor neuron number "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

Allelic Composition: Ptprdtm1Yiw/Ptprd+,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprdtm1Yiw Ptprstm1Mtr

 MP:0001078 abnormal phrenic nerve "malformed or misprojection of motor and sensory neuron axons to the diaphragm and other tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

Allelic Composition: Ptprdtm1Yiw/Ptprdtm1Yiw,Ptprstm1Mtr/Ptprs+
Genetic Background: B6.Cg-Ptprdtm1Yiw Ptprstm1Mtr

Allelic Composition: Ptprdtm1Yiw/Ptprd+,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprdtm1Yiw Ptprstm1Mtr

 MP:0001201 translucent skin "skin that is more transparent to light than normal " [J:15108]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0001244 thin dermal layer "reduced thickness of the dermis" [J:65030]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Pkd1tm1Maa/Pkd1tm1Maa
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001302 eyelids open at birth "widely open eyes instead of closed at perinatal stage" [J:51966]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pkd1tm1Maa/Pkd1tm1Maa
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nfkb2tm1Sbn/Nfkb2tm1Sbn
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0002192 hydrops fetalis "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptpn12tm1b(NCOM)Mfgc/Ptpn12tm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Ptpn12tm1b(NCOM)Mfgc/Tcp

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0002639 micrognathia "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0002741 small olfactory bulb "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0002971 abnormal brown fat morphology "defect in the thermogenic form of adipose tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0003359 hypaxial muscle hypoplasia "reduced cell number in the muscles of the limbs" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0003586 ureter dilation "abnormal distention of the ureter due to accumulation of fluid" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0003651 abnormal axon outgrowth "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0003672 abnormal ureter development "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0004017 duplex kidney "a kidney that is split into two separate collecting systems; there may be a duplex ureter or a single ureter; may present unilaterally or bilaterally" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0004701 decreased circulating insulin-like growth factor I level "reduced blood concentration of this polypeptide hormone with growth-regulating, insulin-like, and mitogenic activities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr,Rtn4rtm1.1Pado/Rtn4rtm1.1Pado,Rtn4rl1tm1.1Rojg/Rtn4rl1tm1.1Rojg
Genetic Background: involves: 129S/SvEvBrd * 129S4/SvJae

 MP:0005150 cachexia "general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pkd1tm1Maa/Pkd1tm1Maa
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005162 carpoptosis "paralysis of the extensors of the wrist and fingers; most often caused by a lesion of the radial nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:81738]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0005361 small pituitary gland "reduced size of the pituitary gland, the compound gland suspended from the base of the hypothalamus, which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0006069 abnormal retinal neuronal layer morphology "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0008512 disorganized retinal inner nuclear layer "derangement of the normal pattern of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0008544 impaired olfaction "reduced ability to detect odors" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0009009 absent estrous cycle "failure of female animals to enter or progress through their sexual cycle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0009021 absent estrus "absence or failure of the estrous phase of the estrous cycle in female animals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0009887 abnormal palatal shelf fusion at midline "any anomaly in the process in which the palatal shelves grow toward the midline and adhere along the medial edge epithelia, forming the midline epithelial seam which disappears in later stages" [PMID:16942766]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0010934 increased subcutaneous adipose tissue amount "increase in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Pkd1tm1Maa/Pkd1tm1Maa
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

 MP:0011493 double ureter "two ureters open separately into the renal pelvis superiorly and drain separately into the urinary bladder or genital tract; if two ureteral buds arise from the Wolffian duct, a duplex kidney with complete ureteral duplication ensues" [http://emedicine.medscape.com/article/378075-overview, MGI:anna]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0011767 ureterocele "saccular dilation of the terminal portion of the ureter that protrudes into the lumen of the urinary bladder, probably due to a congenital stenosis of the ureteric orifice meatus; most often associated with a duplicated collection system, where two ureters drain their respective kidney instead of one" [MGI:anna]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0012538 persistent hyaloid artery "incomplete regression of the hyaloid artery, usually accompanied by persistence of the hyperplastic primary vitreous; small remnants of the artery may remain with free remnants sometimes seen as floating material (aka muscae volitantes); an anterior remnant of the hyaloid artery can be seen as Mittendorf s dot, a small pinpoint-like scar on the posterior surface of the lens; a posterior remnant may be seen where the artery left the optic disc, and is known as Bergmeister s papilla" [MGI:anna]
Show

Allelic Composition: Ptprftm1Wjh/Ptprftm1Wjh,Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: B6.Cg-Ptprftm1Wjh Ptprstm1Mtr

 MP:0030013 improved central nervous system regeneration "faster or more complete regeneration of healthy central nervous system tissue following injury or disease" [] {comment="MGI:anna"}
Show

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr
Genetic Background: involves: 129/Sv * BALB/c

Allelic Composition: Ptprstm1Mtr/Ptprstm1Mtr,Rtn4rtm1.1Pado/Rtn4rtm1.1Pado,Rtn4rl1tm1.1Rojg/Rtn4rl1tm1.1Rojg
Genetic Background: involves: 129S/SvEvBrd * 129S4/SvJae

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003863 P60469 / Ppfia3 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 / O75145* / PTPRF interacting protein alpha 3*  / complex / reaction
 ENSMUSG00000016487 Q8C8U0 / Ppfibp1 / PTPRF interacting protein, binding protein 1 (liprin beta 1) / Q86W92* / PPFIA binding protein 1*  / reaction / complex
 ENSMUSG00000059146 Ntrk3 / Q6VNS1 / NT-3 growth factor receptor / Q16288* / neurotrophic receptor tyrosine kinase 3*  / complex / reaction
 ENSMUSG00000036528 O35711 / Ppfibp2 / PTPRF interacting protein, binding protein 2 (liprin beta 2) / Q8ND30* / PPFIA binding protein 2*  / reaction / complex
 ENSMUSG00000053825 Ppfia2 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 / O75334* / PTPRF interacting protein alpha 2*  / reaction / complex
 ENSMUSG00000045045 Lrfn4 / Q80XU8 / Leucine-rich repeat and fibronectin type-III domain-containing protein 4 / Q6PJG9* / leucine rich repeat and fibronectin type III domain containing 4*  / reaction / complex
 ENSMUSG00000047085 Lrrc4b / P0C192 / Leucine-rich repeat-containing protein 4B / Q9NT99* / leucine rich repeat containing 4B*  / reaction / complex
 ENSMUSG00000037519 Ppfia1 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 / Q13136* / PTPRF interacting protein alpha 1*  / reaction / complex
 ENSMUSG00000026458 Ppfia4 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 / O75335* / PTPRF interacting protein alpha 4*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr