ENSMUSG00000003863


Mus musculus

Features
Gene ID: ENSMUSG00000003863
  
Biological name :Ppfia3
  
Synonyms : P60469 / Ppfia3 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
  
Possible biological names infered from orthology : O75145 / PTPRF interacting protein alpha 3
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B3
Gene start: 45339122
Gene end: 45367019
  
Corresponding Affymetrix probe sets: 10563220 (MoGene1.0st)   1431046_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003961
Ensembl peptide - ENSMUSP00000147584
Ensembl peptide - ENSMUSP00000148200
NCBI entrez gene - 76787     See in Manteia.
MGI - MGI:1924037
RefSeq - XM_011250914
RefSeq - NM_029741
RefSeq - XM_006541273
RefSeq - XM_011250912
RefSeq Peptide - NP_084017
swissprot - A0A1B0GRM4
swissprot - P60469
Ensembl - ENSMUSG00000003863
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppfia3ENSDARG00000077053Danio rerio
 O75145ENSG00000177380Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppfia1 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 / Q13136* / PTPRF interacting protein alpha 1*ENSMUSG0000003751965
Ppfia2 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 / O75334* / PTPRF interacting protein alpha 2*ENSMUSG0000005382562
Ppfia4 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 / O75335* / PTPRF interacting protein alpha 4*ENSMUSG0000002645860
O35711 / Ppfibp2 / PTPRF interacting protein, binding protein 2 (liprin beta 2) / Q8ND30* / PPFIA binding protein 2*ENSMUSG0000003652818
Q8C8U0 / Ppfibp1 / PTPRF interacting protein, binding protein 1 (liprin beta 1) / Q86W92* / PPFIA binding protein 1*ENSMUSG0000001648717
Kazn / Q69ZS8 / Kazrin / Q674X7* / kazrin, periplakin interacting protein*ENSMUSG000000406068


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR029515  LAR-interacting protein, Liprin
 IPR030440  Liprin-alpha-3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0048172 regulation of short-term neuronal synaptic plasticity ISS
 cellular_componentGO:0001669 acrosomal vesicle ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0048786 presynaptic active zone IEA
 cellular_componentGO:0098875 epididymosome ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Serotonin Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Dopamine Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000013236 Ptprs / B0V2N1 / Receptor-type tyrosine-protein phosphatase S / Q13332* / protein tyrosine phosphatase, receptor type S*  / reaction / complex
 ENSMUSG00000028399 Ptprd / Q64487 / protein tyrosine phosphatase, receptor type, D / P23468*  / reaction / complex
 ENSMUSG00000033295 Ptprf / A2A8L5 / Receptor-type tyrosine-protein phosphatase F / P10586* / protein tyrosine phosphatase, receptor type F*  / reaction / complex
 ENSMUSG00000034156 Q7TNF8 / Tspoap1 / Peripheral-type benzodiazepine receptor-associated protein 1 / O95153* / TSPO associated protein 1*  / complex
 ENSMUSG00000028456 Q9Z1N9 / Unc13b / unc-13 homolog B (C. elegans) / O14795* / unc-13 homolog B*  / complex






 

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