ENSGALG00000006785


Gallus gallus

Features
Gene ID: ENSGALG00000006785
  
Biological name :IRF1
  
Synonyms : Interferon regulatory factor 1 / IRF1 / Q90876
  
Possible biological names infered from orthology : P10914 / P15314
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 16977371
Gene end: 16983282
  
Corresponding Affymetrix probe sets: Gga.791.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002242
NCBI entrez gene - 396384     See in Manteia.
RefSeq - XM_015294015
RefSeq - NM_205415
RefSeq - XM_015294014
RefSeq Peptide - NP_990746
swissprot - Q90876
swissprot - M4M675
Ensembl - ENSGALG00000006785
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irf1bENSDARG00000043249Danio rerio
 IRF1ENSG00000125347Homo sapiens
 Irf1ENSMUSG00000018899Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRF2 / Q98925 / Interferon regulatory factor 2 / P14316* / P23906*ENSGALG0000001064239
IRF8 / Q90871 / Interferon regulatory factor 8 / P23611* / Q02556*ENSGALG0000000575721
IRF4 / Q15306* / Q64287* / interferon regulatory factor 4*ENSGALG0000001283020
IRF6 / interferon regulatory factor 6 / O14896* / P97431*ENSGALG0000000140520
IRF5 / Gallus gallus interferon regulatory factor 5 (IRF5), mRNA. / P56477* / Q13568* / interferon regulatory factor 5*ENSGALG0000003998219
IRF9 / interferon regulatory factor 9 ENSGALG0000003029118
IRF7 / interferon regulatory factor 3 / P70434* / Q92985* / interferon regulatory factor 7*ENSGALG0000001429717
IRF4* / Q15306* / Q64287* / interferon regulatory factor 4*ENSGALG0000004391316


Protein motifs (from Interpro)
Interpro ID Name
 IPR001346  Interferon regulatory factor DNA-binding domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017431  Interferon regulatory factor-1/2
 IPR019817  Interferon regulatory factor, conserved site
 IPR031215  Interferon regulatory factor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0032481 positive regulation of type I interferon production IEA
 biological_processGO:0032728 positive regulation of interferon-beta production IEA
 biological_processGO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway IEA
 biological_processGO:0035458 cellular response to interferon-beta IEA
 biological_processGO:0043374 CD8-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0045084 positive regulation of interleukin-12 biosynthetic process IEA
 biological_processGO:0045590 negative regulation of regulatory T cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050776 regulation of immune response IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway IEA
 biological_processGO:0071260 cellular response to mechanical stimulus IEA
 biological_processGO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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