ENSGALG00000014297


Gallus gallus

Features
Gene ID: ENSGALG00000014297
  
Biological name :IRF7
  
Synonyms : interferon regulatory factor 3 / IRF7
  
Possible biological names infered from orthology : interferon regulatory factor 7 / P70434 / Q92985
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 15845877
Gene end: 15849344
  
Corresponding Affymetrix probe sets: Gga.1087.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038233
NCBI entrez gene - 396330     See in Manteia.
RefSeq - NM_205372
RefSeq Peptide - NP_990703
swissprot - Q90ZD4
Ensembl - ENSGALG00000014297
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irf7ENSDARG00000045661Danio rerio
 IRF7ENSG00000185507Homo sapiens
 Irf7ENSMUSG00000025498Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRF5 / Gallus gallus interferon regulatory factor 5 (IRF5), mRNA. / P56477* / Q13568* / interferon regulatory factor 5*ENSGALG0000003998222
IRF6 / interferon regulatory factor 6 / O14896* / P97431*ENSGALG0000000140521
IRF4 / Q15306* / Q64287* / interferon regulatory factor 4*ENSGALG0000001283020
IRF8 / Q90871 / Interferon regulatory factor 8 / P23611* / Q02556*ENSGALG0000000575719
IRF9 / interferon regulatory factor 9 ENSGALG0000003029118
IRF1 / Q90876 / Interferon regulatory factor 1 / P10914* / P15314*ENSGALG0000000678511
IRF2 / Q98925 / Interferon regulatory factor 2 / P14316* / P23906*ENSGALG0000001064210
IRF4* / Q15306* / Q64287* / interferon regulatory factor 4*ENSGALG0000004391310


Protein motifs (from Interpro)
Interpro ID Name
 IPR001346  Interferon regulatory factor DNA-binding domain
 IPR008984  SMAD/FHA domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017855  SMAD-like domain superfamily
 IPR019471  Interferon regulatory factor-3
 IPR019817  Interferon regulatory factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002819 regulation of adaptive immune response IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016064 immunoglobulin mediated immune response IEA
 biological_processGO:0032481 positive regulation of type I interferon production IEA
 biological_processGO:0032607 interferon-alpha production IEA
 biological_processGO:0032608 interferon-beta production IEA
 biological_processGO:0032727 positive regulation of interferon-alpha production IEA
 biological_processGO:0032728 positive regulation of interferon-beta production IEA
 biological_processGO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway IEA
 biological_processGO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway IEA
 biological_processGO:0045351 type I interferon biosynthetic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060340 positive regulation of type I interferon-mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
TICAM1-dependent activation of IRF3/IRF7
TRAF6 mediated IRF7 activation
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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