ENSGALG00000005757


Gallus gallus

Features
Gene ID: ENSGALG00000005757
  
Biological name :IRF8
  
Synonyms : Interferon regulatory factor 8 / IRF8 / Q90871
  
Possible biological names infered from orthology : P23611 / Q02556
  
Species: Gallus gallus
  
Chr. number: 11
Strand: -1
Band:
Gene start: 17821801
Gene end: 17827332
  
Corresponding Affymetrix probe sets: Gga.4418.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009229
NCBI entrez gene - 396385     See in Manteia.
RefSeq - XM_015292553
RefSeq - NM_205416
RefSeq - XM_015292551
RefSeq - XM_015292552
RefSeq Peptide - NP_990747
swissprot - Q90871
swissprot - R9PXM4
Ensembl - ENSGALG00000005757
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irf8ENSDARG00000056407Danio rerio
 IRF8ENSG00000140968Homo sapiens
 Irf8ENSMUSG00000041515Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRF4 / Q15306* / Q64287* / interferon regulatory factor 4*ENSGALG0000001283043
IRF9 / interferon regulatory factor 9 ENSGALG0000003029136
IRF6 / interferon regulatory factor 6 / O14896* / P97431*ENSGALG0000000140531
IRF5 / Gallus gallus interferon regulatory factor 5 (IRF5), mRNA. / P56477* / Q13568* / interferon regulatory factor 5*ENSGALG0000003998228
IRF7 / interferon regulatory factor 3 / P70434* / Q92985* / interferon regulatory factor 7*ENSGALG0000001429722
IRF4* / Q15306* / Q64287* / interferon regulatory factor 4*ENSGALG0000004391321
IRF2 / Q98925 / Interferon regulatory factor 2 / P14316* / P23906*ENSGALG0000001064217
IRF1 / Q90876 / Interferon regulatory factor 1 / P10914* / P15314*ENSGALG0000000678516


Protein motifs (from Interpro)
Interpro ID Name
 IPR001346  Interferon regulatory factor DNA-binding domain
 IPR008984  SMAD/FHA domain superfamily
 IPR011991  ArsR-like helix-turn-helix domain
 IPR017855  SMAD-like domain superfamily
 IPR019471  Interferon regulatory factor-3
 IPR019817  Interferon regulatory factor, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006909 phagocytosis IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0009617 response to bacterium IEA
 biological_processGO:0030099 myeloid cell differentiation IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032735 positive regulation of interleukin-12 production IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0042832 defense response to protozoan IEA
 biological_processGO:0044130 negative regulation of growth of symbiont in host IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071346 cellular response to interferon-gamma IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr