ENSGALG00000011182


Gallus gallus

Features
Gene ID: ENSGALG00000011182
  
Biological name :DLL1
  
Synonyms : delta-like protein 1 precursor / DLL1
  
Possible biological names infered from orthology : delta like canonical Notch ligand 1 / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form / O00548 / Q61483
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 40973214
Gene end: 40979620
  
Corresponding Affymetrix probe sets: Gga.2283.1.S1_at (Chicken Array)   Gga.2283.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036909
NCBI entrez gene - 395820     See in Manteia.
RefSeq - NM_204973
RefSeq Peptide - NP_990304
swissprot - F1NRS3
Ensembl - ENSGALG00000011182
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlaENSDARG00000010791Danio rerio
 dldENSDARG00000020219Danio rerio
 DLL1ENSG00000198719Homo sapiens
 Dll1ENSMUSG00000014773Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DLL4 / delta like canonical Notch ligand 4 / Q9JI71* / Q9NR61* / Delta-like protein 4 *ENSGALG0000000851450
JAG2 / jagged 2 / Q9QYE5* / Q9Y219* / Protein jagged-2 *ENSGALG0000001169632
NOTCH1 / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSGALG0000000237527
NOTCH2 / Q04721*ENSGALG0000000292226
JAG1 / jagged 1 / P78504* / Q9QXX0* / Protein jagged-1 *ENSGALG0000000902024
SNED1 / sushi, nidogen and EGF like domains 1 / Q8TER0*ENSGALG0000004359617
ENSGALG0000001618310
ENSGALG000000399979


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001774  Delta/Serrate/lag-2 (DSL) protein
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011651  Notch ligand, N-terminal domain
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IEA
 biological_processGO:0001757 somite specification IEA
 biological_processGO:0001947 heart looping IEA
 biological_processGO:0002315 marginal zone B cell differentiation IEA
 biological_processGO:0003323 type B pancreatic cell development IEA
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IEA
 biological_processGO:0007386 compartment pattern specification IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009954 proximal/distal pattern formation IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0014002 astrocyte development IEA
 biological_processGO:0014807 regulation of somitogenesis IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0021688 cerebellar molecular layer formation IEA
 biological_processGO:0021693 cerebellar Purkinje cell layer structural organization IEA
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0030857 negative regulation of epithelial cell differentiation IEA
 biological_processGO:0032693 negative regulation of interleukin-10 production IEA
 biological_processGO:0034351 negative regulation of glial cell apoptotic process IEA
 biological_processGO:0035265 organ growth IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0045596 negative regulation of cell differentiation IEA
 biological_processGO:0045605 negative regulation of epidermal cell differentiation IEA
 biological_processGO:0045608 negative regulation of inner ear auditory receptor cell differentiation IEA
 biological_processGO:0045638 negative regulation of myeloid cell differentiation IEA
 biological_processGO:0045662 negative regulation of myoblast differentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:0045807 positive regulation of endocytosis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046331 lateral inhibition IEA
 biological_processGO:0048630 skeletal muscle tissue growth IEA
 biological_processGO:0048631 regulation of skeletal muscle tissue growth IEA
 biological_processGO:0048633 positive regulation of skeletal muscle tissue growth IEA
 biological_processGO:0048665 neuron fate specification IEA
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0051302 regulation of cell division IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0060042 retina morphogenesis in camera-type eye IEA
 biological_processGO:0060853 Notch signaling pathway involved in arterial endothelial cell fate commitment IEA
 biological_processGO:0070986 left/right axis specification IEA
 biological_processGO:0072006 nephron development IEA
 biological_processGO:0072014 proximal tubule development IEA
 biological_processGO:0072070 loop of Henle development IEA
 biological_processGO:0097102 endothelial tip cell fate specification IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEA
 biological_processGO:0098773 skin epidermis development IEA
 biological_processGO:1900746 regulation of vascular endothelial growth factor signaling pathway IEA
 biological_processGO:1903672 positive regulation of sprouting angiogenesis IEA
 biological_processGO:2000726 negative regulation of cardiac muscle cell differentiation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0005112 Notch binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0030957 Tat protein binding IEA
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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