ENSGALG00000011696


Gallus gallus

Features
Gene ID: ENSGALG00000011696
  
Biological name :JAG2
  
Synonyms : JAG2 / jagged 2
  
Possible biological names infered from orthology : Protein jagged-2 / Q9QYE5 / Q9Y219
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 52195852
Gene end: 52255454
  
Corresponding Affymetrix probe sets: Gga.12817.1.S1_at (Chicken Array)   Gga.4932.1.S1_at (Chicken Array)   GgaAffx.24136.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046042
Ensembl peptide - ENSGALP00000021520
NCBI entrez gene - 776138     See in Manteia.
RefSeq - XM_004936419
RefSeq - XM_001235688
swissprot - F1NMD6
swissprot - A0A1D5P068
Ensembl - ENSGALG00000011696
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 jag2aENSDARG00000014246Danio rerio
 jag2bENSDARG00000021389Danio rerio
 JAG2ENSG00000184916Homo sapiens
 Jag2ENSMUSG00000002799Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
JAG1 / jagged 1 / P78504* / Q9QXX0* / Protein jagged-1 *ENSGALG0000000902047
NOTCH2 / Q04721*ENSGALG0000000292227
NOTCH1 / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*ENSGALG0000000237527
DLL1 / delta-like protein 1 precursor / O00548* / Q61483* / delta like canonical Notch ligand 1* / Delta-like protein 1 Dll1-soluble form Dll1-derived cell-associated form Dll1-intracellular form*ENSGALG0000001118218
DLL4 / delta like canonical Notch ligand 4 / Q9JI71* / Q9NR61* / Delta-like protein 4 *ENSGALG0000000851417
SNED1 / sushi, nidogen and EGF like domains 1 / Q8TER0*ENSGALG0000004359616
ENSGALG0000001618312
ENSGALG000000399978


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001007  VWFC domain
 IPR001774  Delta/Serrate/lag-2 (DSL) protein
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011651  Notch ligand, N-terminal domain
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026219  Jagged/Serrate protein
 IPR033108  Protein jagged-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0003016 respiratory system process IEA
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0009912 auditory receptor cell fate commitment IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016331 morphogenesis of embryonic epithelium IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0030217 T cell differentiation IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 biological_processGO:0042492 gamma-delta T cell differentiation IEA
 biological_processGO:0045061 thymic T cell selection IEA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:1990134 epithelial cell apoptotic process involved in palatal shelf morphogenesis IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005112 Notch binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Activated NOTCH1 Transmits Signal to the Nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002375 NOTCH1 / P46531* / Q01705* / Neurogenic locus notch homolog protein 1 Notch 1 extracellular truncation Notch 1 intracellular domain*  / reaction / complex






 

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