ENSGALG00000011680


Gallus gallus

Features
Gene ID: ENSGALG00000011680
  
Biological name :EPHA5
  
Synonyms : EPHA5 / ephrin type-A receptor 5 precursor
  
Possible biological names infered from orthology : EPH receptor A5 / Ephrin type-A receptor 5 / P54756 / Q60629
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 51398618
Gene end: 51596976
  
Corresponding Affymetrix probe sets: Gga.3047.1.S1_at (Chicken Array)   Gga.3047.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051283
Ensembl peptide - ENSGALP00000019068
Ensembl peptide - ENSGALP00000037020
NCBI entrez gene - 395997     See in Manteia.
RefSeq - XM_015276151
RefSeq - XM_015276147
RefSeq - XM_015276148
RefSeq - XM_015276149
RefSeq - XM_015276150
RefSeq - NM_205105
RefSeq - XM_015276139
RefSeq - XM_015276140
RefSeq - XM_015276141
RefSeq - XM_015276142
RefSeq - XM_015276143
RefSeq - XM_015276144
RefSeq - XM_015276145
RefSeq - XM_015276146
RefSeq Peptide - NP_990436
swissprot - F1NC62
swissprot - F1NSE6
swissprot - A0A1D5PES4
Ensembl - ENSGALG00000011680
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CT990561.1ENSDARG00000058284Danio rerio
 EPHA5ENSG00000145242Homo sapiens
 Epha5ENSMUSG00000029245Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPHA3 / ephrin type-A receptor 3 precursor / P29320* / EPH receptor A3*ENSGALG0000001540367
EPHA4 / ephrin type-A receptor 4 precursor / Q03137* / P54764* / EPH receptor A4* / Ephrin type-A receptor 4 *ENSGALG0000000525663
EPHA7 / O42422 / Ephrin type-A receptor 7 / Q15375* / Q61772* / EPH receptor A7*ENSGALG0000001559363
EPHA8 / EPH receptor A8 / O09127* / P29322* / Ephrin type-A receptor 8 *ENSGALG0000002156760
EPHB2 / EPH receptor B2 / P29323* / P54763* / Ephrin type-B receptor 2 *ENSGALG0000000474156
EPHB1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *ENSGALG0000000660955
EPHB3 / EPH receptor B3 / P54753* / P54754* / Ephrin type-B receptor 3 *ENSGALG0000000853754
EPHB6 / ephrin type-B receptor 5 precursor / O08644* / EPH receptor B6* / Ephrin type-B receptor 6 *ENSGALG0000001474950
EPHA6 / EPH receptor A6 / Q9UF33*ENSGALG0000001541843


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR027936  Ephrin receptor, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0071372 cellular response to follicle-stimulating hormone stimulus IEA
 biological_processGO:1904322 cellular response to forskolin IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005004 GPI-linked ephrin receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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