ENSGALG00000015403


Gallus gallus

Features
Gene ID: ENSGALG00000015403
  
Biological name :EPHA3
  
Synonyms : EPHA3 / ephrin type-A receptor 3 precursor
  
Possible biological names infered from orthology : EPH receptor A3 / P29320
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 89165149
Gene end: 89382603
  
Corresponding Affymetrix probe sets: Gga.805.1.S1_at (Chicken Array)   Gga.805.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024798
NCBI entrez gene - 396402     See in Manteia.
RefSeq - NM_205430
RefSeq - XM_015295857
RefSeq Peptide - NP_990761
swissprot - F1NJX6
Ensembl - ENSGALG00000015403
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epha3ENSDARG00000039373Danio rerio
 EPHA3ENSG00000044524Homo sapiens
 Epha3ENSMUSG00000052504Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPHA5 / ephrin type-A receptor 5 precursor / Q60629* / P54756* / EPH receptor A5* / Ephrin type-A receptor 5 *ENSGALG0000001168069
EPHA4 / ephrin type-A receptor 4 precursor / Q03137* / P54764* / EPH receptor A4* / Ephrin type-A receptor 4 *ENSGALG0000000525664
EPHA7 / O42422 / Ephrin type-A receptor 7 / Q15375* / Q61772* / EPH receptor A7*ENSGALG0000001559363
EPHA8 / EPH receptor A8 / O09127* / P29322* / Ephrin type-A receptor 8 *ENSGALG0000002156760
EPHB2 / EPH receptor B2 / P29323* / P54763* / Ephrin type-B receptor 2 *ENSGALG0000000474156
EPHB1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *ENSGALG0000000660956
EPHB3 / EPH receptor B3 / P54753* / P54754* / Ephrin type-B receptor 3 *ENSGALG0000000853754
EPHB6 / ephrin type-B receptor 5 precursor / O08644* / EPH receptor B6* / Ephrin type-B receptor 6 *ENSGALG0000001474951
EPHA6 / EPH receptor A6 / Q9UF33*ENSGALG0000001541845


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR027936  Ephrin receptor, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0045806 negative regulation of endocytosis IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0051893 regulation of focal adhesion assembly IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005004 GPI-linked ephrin receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr