ENSGALG00000015593


Gallus gallus

Features
Gene ID: ENSGALG00000015593
  
Biological name :EPHA7
  
Synonyms : EPHA7 / Ephrin type-A receptor 7 / O42422
  
Possible biological names infered from orthology : EPH receptor A7 / Q15375 / Q61772
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 74171528
Gene end: 74327787
  
Corresponding Affymetrix probe sets: Gga.4157.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058154
Ensembl peptide - ENSGALP00000025098
NCBI entrez gene - 395967     See in Manteia.
RefSeq - XM_015284601
RefSeq - NM_205083
RefSeq - XM_015284598
RefSeq - XM_015284599
RefSeq - XM_015284600
RefSeq Peptide - NP_990414
swissprot - O42422
swissprot - A0A1D5PYU6
Ensembl - ENSGALG00000015593
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 epha7ENSDARG00000004635Danio rerio
 EPHA7ENSG00000135333Homo sapiens
 Epha7ENSMUSG00000028289Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPHA5 / ephrin type-A receptor 5 precursor / Q60629* / P54756* / EPH receptor A5* / Ephrin type-A receptor 5 *ENSGALG0000001168064
EPHA4 / ephrin type-A receptor 4 precursor / Q03137* / P54764* / EPH receptor A4* / Ephrin type-A receptor 4 *ENSGALG0000000525663
EPHA3 / ephrin type-A receptor 3 precursor / P29320* / EPH receptor A3*ENSGALG0000001540363
EPHA8 / EPH receptor A8 / O09127* / P29322* / Ephrin type-A receptor 8 *ENSGALG0000002156760
EPHB2 / EPH receptor B2 / P29323* / P54763* / Ephrin type-B receptor 2 *ENSGALG0000000474157
EPHB1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *ENSGALG0000000660956
EPHB3 / EPH receptor B3 / P54753* / P54754* / Ephrin type-B receptor 3 *ENSGALG0000000853755
EPHB6 / ephrin type-B receptor 5 precursor / O08644* / EPH receptor B6* / Ephrin type-B receptor 6 *ENSGALG0000001474952
EPHA6 / EPH receptor A6 / Q9UF33*ENSGALG0000001541842


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR027936  Ephrin receptor, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0022407 regulation of cell-cell adhesion IEA
 biological_processGO:0031290 retinal ganglion cell axon guidance IEA
 biological_processGO:0031952 regulation of protein autophosphorylation IEA
 biological_processGO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043525 positive regulation of neuron apoptotic process IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0048671 negative regulation of collateral sprouting IEA
 biological_processGO:0048755 branching morphogenesis of a nerve IEA
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0050919 negative chemotaxis IEA
 biological_processGO:0051964 negative regulation of synapse assembly IEA
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0072178 nephric duct morphogenesis IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005004 GPI-linked ephrin receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008046 axon guidance receptor activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0045499 chemorepellent activity IEA


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHA-mediated growth cone collapse
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr