ENSGALG00000014749


Gallus gallus

Features
Gene ID: ENSGALG00000014749
  
Biological name :EPHB6
  
Synonyms : EPHB6 / ephrin type-B receptor 5 precursor
  
Possible biological names infered from orthology : EPH receptor B6 / Ephrin type-B receptor 6 / O08644
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 77978178
Gene end: 78032477
  
Corresponding Affymetrix probe sets: Gga.633.1.S1_at (Chicken Array)   Gga.633.1.S2_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023737
NCBI entrez gene - 418308     See in Manteia.
RefSeq - XM_015293482
RefSeq - NM_001004387
RefSeq - XM_015293473
RefSeq - XM_015293476
RefSeq - XM_015293471
RefSeq Peptide - NP_001004387
swissprot - F1NAX7
Ensembl - ENSGALG00000014749
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ephb6ENSDARG00000057729Danio rerio
 EPHB6ENSG00000106123Homo sapiens
 Ephb6ENSMUSG00000029869Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EPHB2 / EPH receptor B2 / P29323* / P54763* / Ephrin type-B receptor 2 *ENSGALG0000000474163
EPHB1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *ENSGALG0000000660960
EPHB3 / EPH receptor B3 / P54753* / P54754* / Ephrin type-B receptor 3 *ENSGALG0000000853757
EPHA4 / ephrin type-A receptor 4 precursor / Q03137* / P54764* / EPH receptor A4* / Ephrin type-A receptor 4 *ENSGALG0000000525651
EPHA7 / O42422 / Ephrin type-A receptor 7 / Q15375* / Q61772* / EPH receptor A7*ENSGALG0000001559351
EPHA5 / ephrin type-A receptor 5 precursor / Q60629* / P54756* / EPH receptor A5* / Ephrin type-A receptor 5 *ENSGALG0000001168050
EPHA3 / ephrin type-A receptor 3 precursor / P29320* / EPH receptor A3*ENSGALG0000001540350
EPHA8 / EPH receptor A8 / O09127* / P29322* / Ephrin type-A receptor 8 *ENSGALG0000002156748
EPHA6 / EPH receptor A6 / Q9UF33*ENSGALG0000001541836


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001090  Ephrin receptor ligand binding domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001426  Tyrosine-protein kinase, receptor class V, conserved site
 IPR001660  Sterile alpha motif domain
 IPR003961  Fibronectin type III
 IPR008266  Tyrosine-protein kinase, active site
 IPR008979  Galactose-binding-like domain superfamily
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011009  Protein kinase-like domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016257  Ephrin receptor type-A /type-B
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR027936  Ephrin receptor, transmembrane domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001806 type IV hypersensitivity IEA
 biological_processGO:0002456 T cell mediated immunity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0050663 cytokine secretion IEA
 biological_processGO:0050798 activated T cell proliferation IEA
 biological_processGO:2000525 positive regulation of T cell costimulation IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0005003 ephrin receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr