ENSGALG00000015620


Gallus gallus

Features
Gene ID: ENSGALG00000015620
  
Biological name :XRCC4
  
Synonyms : X-ray repair cross complementing 4 / XRCC4
  
Possible biological names infered from orthology : Q13426 / X-ray repair complementing defective repair in Chinese hamster cells 4
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 62788279
Gene end: 62969042
  
Corresponding Affymetrix probe sets: Gga.10940.1.S1_at (Chicken Array)   Gga.9241.1.S1_at (Chicken Array)   GgaAffx.24733.1.S1_at (Chicken Array)   GgaAffx.24733.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055479
Ensembl peptide - ENSGALP00000025133
NCBI entrez gene - 427325     See in Manteia.
RefSeq - XM_424905
RefSeq - XM_015280684
RefSeq - XM_015280685
swissprot - F1NDC0
swissprot - A0A1D5PRF4
Ensembl - ENSGALG00000015620
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xrcc4ENSDARG00000010732Danio rerio
 XRCC4ENSG00000152422Homo sapiens
 Xrcc4ENSMUSG00000021615Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009089  XRCC4, N-terminal domain superfamily
 IPR010585  DNA repair protein XRCC4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006302 double-strand break repair IEA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0010165 response to X-ray IEA
 biological_processGO:0051103 DNA ligation involved in DNA repair IEA
 biological_processGO:0051351 positive regulation of ligase activity IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex IEA
 cellular_componentGO:0032807 DNA ligase IV complex IEA
 cellular_componentGO:0070419 nonhomologous end joining complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins
Nonhomologous End-Joining (NHEJ)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007753 POLL / DNA polymerase lambda / Q9QXE2* / Q9UGP5* / polymerase (DNA directed), lambda*  / reaction
 ENSGALG00000011492 XRCC5 / X-ray repair cross complementing 5 / P13010* / P27641* / X-ray repair complementing defective repair in Chinese hamster cells 5*  / reaction
 ENSGALG00000008435 SUMO1 / Q8QGH2 / Small ubiquitin-related modifier 1 / P63166* / P63165* / small ubiquitin-like modifier 1*  / reaction / complex
 ENSGALG00000015620 XRCC4 / X-ray repair cross complementing 4 / Q13426* / X-ray repair complementing defective repair in Chinese hamster cells 4*  / complex
 ENSGALG00000006428 UBE2I / P63283 / SUMO-conjugating enzyme UBC9 / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSGALG00000016854 LIG4 / DNA ligase 4 / P49917* / Q8BTF7* / ligase IV, DNA, ATP-dependent*  / complex






 

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