ENSGALG00000015666


Gallus gallus

Features
Gene ID: ENSGALG00000015666
  
Biological name :TNIP2
  
Synonyms : TNFAIP3 interacting protein 2 / TNIP2
  
Possible biological names infered from orthology : Q8NFZ5 / Q99JG7
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 83016901
Gene end: 83024840
  
Corresponding Affymetrix probe sets: GgaAffx.9983.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044555
Ensembl peptide - ENSGALP00000025217
NCBI entrez gene - 422884     See in Manteia.
RefSeq - XM_015285792
RefSeq - NM_001031166
RefSeq Peptide - NP_001026337
swissprot - A0A1D5NW22
swissprot - F1ND53
Ensembl - ENSGALG00000015666
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnip2ENSDARG00000074501Danio rerio
 TNIP2ENSG00000168884Homo sapiens
 Tnip2ENSMUSG00000059866Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR022008  TSG101 and ALIX binding domain of CEP55


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0023035 CD40 signaling pathway IEA
 biological_processGO:0034134 toll-like receptor 2 signaling pathway IEA
 biological_processGO:0034138 toll-like receptor 3 signaling pathway IEA
 biological_processGO:0034162 toll-like receptor 9 signaling pathway IEA
 biological_processGO:0043032 positive regulation of macrophage activation IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0050871 positive regulation of B cell activation IEA
 biological_processGO:0070498 interleukin-1-mediated signaling pathway IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IEA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
MAP3K8 (TPL2)-dependent MAPK1/3 activation
Ovarian tumor domain proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002229 FBXW11 / F-box and WD repeat domain containing 11 / Q5SRY7* / Q9UKB1* / F-box/WD repeat-containing protein 11 *  / reaction / complex
 ENSGALG00000006474 SKP1 / Q5ZKF5 / S-phase kinase-associated protein 1 / Skp1a* / Q9WTX5* / P63208* / AC104109.3* / S-phase kinase-associated protein 1A*  / reaction / complex
 ENSGALG00000007356 MAP3K8 / mitogen-activated protein kinase kinase kinase 8 / P41279* / Q07174*  / complex / reaction
 ENSGALG00000013861 TNFAIP3 / TNF alpha induced protein 3 / P21580* / Q60769* / tumor necrosis factor, alpha-induced protein 3*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000012304 NFKB1 / Q04861 / Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p50 subunit / P19838* / P25799* / nuclear factor kappa B subunit 1*  / reaction / complex
 ENSGALG00000036941 CUL1 / cullin 1 / Q13616* / Q9WTX6* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction






 

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