ENSGALG00000016843


Gallus gallus

Features
Gene ID: ENSGALG00000016843
  
Biological name :COL4A2
  
Synonyms : COL4A2 / collagen, type IV, alpha 2 precursor
  
Possible biological names infered from orthology : Collagen alpha-2(IV) chain Canstatin / collagen type IV alpha 2 chain / P08122 / P08572
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 138904303
Gene end: 139053712
  
Corresponding Affymetrix probe sets: Gga.19409.1.S1_at (Chicken Array)   Gga.19409.1.S1_s_at (Chicken Array)   Gga.3104.1.S1_at (Chicken Array)   GgaAffx.10782.1.S1_s_at (Chicken Array)   GgaAffx.25090.1.S1_s_at (Chicken Array)   GgaAffx.25090.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027157
NCBI entrez gene - 418752     See in Manteia.
RefSeq - XM_015277858
RefSeq - NM_001162390
RefSeq - XM_015277856
RefSeq - XM_015277857
RefSeq - XM_015277855
RefSeq Peptide - NP_001155862
swissprot - F1P2Q3
Ensembl - ENSGALG00000016843
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 col4a2ENSDARG00000104110Danio rerio
 COL4A2ENSG00000134871Homo sapiens
 Col4a2ENSMUSG00000031503Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
COL4A6 / collagen type IV alpha 6 chain / Q14031* / collagen, type IV, alpha 6*ENSGALG0000000826650
COL4A1 / collagen type IV alpha 1 chain / P02462* / P02463* / Collagen alpha-1(IV) chain Arresten*ENSGALG0000003679846
COL4A5 / collagen type IV alpha 5 chain / P29400* / collagen, type IV, alpha 5*ENSGALG0000000814145
COL4A3 / collagen type IV alpha 3 chain / Q01955* / Q9QZS0* / Collagen alpha-3(IV) chain Tumstatin*ENSGALG0000003861240
COL4A4* / P53420* / Q9QZR9* / Collagen alpha-4(IV) chain * / collagen type IV alpha 4 chain*ENSGALG0000000494633
COL22A1 / collagen alpha-1(XXII) chain precursor / Q8NFW1* / collagen, type XXII, alpha 1* / collagen type XXII alpha 1 chain*ENSGALG0000003802229
COL19A1 / collagen type XIX alpha 1 chain / Q0VF58* / Q14993* / Collagen alpha-1(XIX) chain *ENSGALG0000004358420
COL21A1 / collagen type XXI alpha 1 chain / Q96P44*ENSGALG0000001629216
COL4A4* / P53420* / Q9QZR9* / Collagen alpha-4(IV) chain * / collagen type IV alpha 4 chain*ENSGALG000000431758
Q07092* / Q8BLX7* / COL16A1* / Collagen alpha-1(XVI) chain * / collagen type XVI alpha 1 chain*ENSGALG000000268367


Protein motifs (from Interpro)
Interpro ID Name
 IPR001442  Collagen IV, non-collagenous
 IPR008160  Collagen triple helix repeat
 IPR016187  C-type lectin fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0016525 negative regulation of angiogenesis IEA
 biological_processGO:0035987 endodermal cell differentiation IEA
 biological_processGO:0038063 collagen-activated tyrosine kinase receptor signaling pathway IEA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005587 collagen type IV trimer IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Signaling by PDGF
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Crosslinking of collagen fibrils
Laminin interactions
Non-integrin membrane-ECM interactions
NCAM1 interactions
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016843 COL4A2 / collagen, type IV, alpha 2 precursor / P08122* / P08572* / collagen type IV alpha 2 chain* / Collagen alpha-2(IV) chain Canstatin*  / -
 ENSGALG00000036798 COL4A1 / collagen type IV alpha 1 chain / P02462* / P02463* / Collagen alpha-1(IV) chain Arresten*  / - / complex






 

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