ENSGALG00000028664


Gallus gallus

Features
Gene ID: ENSGALG00000028664
  
Biological name :CKS1B
  
Synonyms : CDC28 protein kinase regulatory subunit 1B / CKS1B
  
Possible biological names infered from orthology : CDC28 protein kinase 1b, retrogene / Cks1brt / Cyclin-dependent kinases regulatory subunit 1 / P61024 / P61025
  
Species: Gallus gallus
  
Chr. number: 25
Strand: 1
Band:
Gene start: 1801173
Gene end: 1802313
  
Corresponding Affymetrix probe sets: Gga.7132.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064805
Ensembl peptide - ENSGALP00000043450
NCBI entrez gene - 100134845     See in Manteia.
RefSeq - NM_001112806
RefSeq Peptide - NP_001106277
swissprot - R4GMI4
swissprot - A0A1L1S0Y9
Ensembl - ENSGALG00000028664
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cks1bENSDARG00000007971Danio rerio
 CKS1BENSG00000173207Homo sapiens
 Cks1bENSMUSG00000028044Mus musculus
 Cks1brtENSMUSG00000062687Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CKS2 / CDC28 protein kinase regulatory subunit 2 / P33552* / P56390* / Cyclin-dependent kinases regulatory subunit 2 *ENSGALG0000003881728


Protein motifs (from Interpro)
Interpro ID Name
 IPR000789  Cyclin-dependent kinase, regulatory subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IBA
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEA
 molecular_functionGO:0019901 protein kinase binding IBA
 molecular_functionGO:0042393 histone binding IBA
 molecular_functionGO:0043130 ubiquitin binding IBA
 molecular_functionGO:0061575 cyclin-dependent protein serine/threonine kinase activator activity IBA


Pathways (from Reactome)
Pathway description
SCF(Skp2)-mediated degradation of p27/p21
Cyclin D associated events in G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000022980 CDKN1B / cyclin dependent kinase inhibitor 1B / P46414* / P46527*  / reaction / complex
 ENSGALG00000006474 SKP1 / Q5ZKF5 / S-phase kinase-associated protein 1 / Skp1a* / Q9WTX5* / P63208* / AC104109.3* / S-phase kinase-associated protein 1A*  / complex / reaction
 ENSGALG00000036941 CUL1 / cullin 1 / Q13616* / Q9WTX6* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*  / reaction / complex
 ENSGALG00000040794 CCNE2 / cyclin E2 / O96020* / Q9Z238* / G1/S-specific cyclin-E2 *  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction / complex






 

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