ENSMUSG00000062687


Mus musculus

Features
Gene ID: ENSMUSG00000062687
  
Biological name :Cks1brt
  
Synonyms : CDC28 protein kinase 1b, retrogene / Cks1brt
  
Possible biological names infered from orthology : CDC28 protein kinase regulatory subunit 1B / CKS1B / P61024
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C3
Gene start: 85151924
Gene end: 85173622
  
Corresponding Affymetrix probe sets: 10573610 (MoGene1.0st)   1438600_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076162
Ensembl peptide - ENSMUSP00000147685
NCBI entrez gene - 624855     See in Manteia.
MGI - MGI:3643620
RefSeq - NM_001037922
RefSeq Peptide - NP_001033011
swissprot - Q3UNC9
Ensembl - ENSMUSG00000062687
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cks1bENSDARG00000007971Danio rerio
 CKS1BENSGALG00000028664Gallus gallus
 CKS1BENSG00000173207Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cks1b / P61025 / Cyclin-dependent kinases regulatory subunit 1 ENSMUSG0000002804477
Cks2 / P56390 / Cyclin-dependent kinases regulatory subunit 2 / P33552* / CDC28 protein kinase regulatory subunit 2*ENSMUSG0000006224863


Protein motifs (from Interpro)
Interpro ID Name
 IPR000789  Cyclin-dependent kinase, regulatory subunit
 IPR036858  Cyclin-dependent kinase, regulatory subunit superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IBA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IBA
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEA
 molecular_functionGO:0019901 protein kinase binding IBA
 molecular_functionGO:0042393 histone binding IBA
 molecular_functionGO:0043130 ubiquitin binding IBA
 molecular_functionGO:0061575 cyclin-dependent protein serine/threonine kinase activator activity IBA


Pathways (from Reactome)
Pathway description
SCF(Skp2)-mediated degradation of p27/p21
Cyclin D associated events in G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029686 Cul1 / Q9WTX6 / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA. / Q13616* / cullin 1*  / complex / reaction
 ENSMUSG00000036309 Skp1a / Q9WTX5 / S-phase kinase-associated protein 1A / SKP1* / P63208* / AC104109.3* / S-phase kinase associated protein 1*  / complex / reaction
 ENSMUSG00000023067 Cdkn1a / P39689 / Cyclin-dependent kinase inhibitor 1 / P38936* / cyclin dependent kinase inhibitor 1A*  / reaction / complex
 ENSMUSG00000031666 Rbl2 / Q64700 / Retinoblastoma-like protein 2 / Q08999* / RB transcriptional corepressor like 2*  / reaction / complex
 ENSMUSG00000002068 Ccne1 / Q61457 / G1/S-specific cyclin-E1 / P24864* / cyclin E1*  / reaction / complex
 ENSMUSG00000054115 Skp2 / Q9Z0Z3 / S-phase kinase-associated protein 2 (p45) / Q13309* / S-phase kinase associated protein 2*  / reaction / complex
 ENSMUSG00000025358 Cdk2 / P97377 / Cyclin-dependent kinase 2 / P24941*  / reaction / complex
 ENSMUSG00000028212 Ccne2 / Q9Z238 / G1/S-specific cyclin-E2 / O96020* / cyclin E2*  / reaction / complex
 ENSMUSG00000003031 Cdkn1b / P46414 / Cyclin-dependent kinase inhibitor 1B / P46527*  / reaction / complex






 

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