ENSMUSG00000000263


Mus musculus

Features
Gene ID: ENSMUSG00000000263
  
Biological name :Glra1
  
Synonyms : Glra1 / Glycine receptor subunit alpha-1 / Q64018
  
Possible biological names infered from orthology : glycine receptor alpha 1 / P23415
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B1.3
Gene start: 55514238
Gene end: 55608198
  
Corresponding Affymetrix probe sets: 10386076 (MoGene1.0st)   1422277_at (Mouse Genome 430 2.0 Array)   1437139_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000075032
Ensembl peptide - ENSMUSP00000099777
Ensembl peptide - ENSMUSP00000104481
NCBI entrez gene - 14654     See in Manteia.
MGI - MGI:95747
RefSeq - NM_020492
RefSeq - NM_001290821
RefSeq Peptide - NP_001277750
RefSeq Peptide - NP_065238
swissprot - Q5NCT9
swissprot - Q5NCU0
swissprot - Q64018
Ensembl - ENSMUSG00000000263
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glra1ENSDARG00000012019Danio rerio
 GLRA1ENSGALG00000004134Gallus gallus
 GLRA1ENSG00000145888Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Glra3 / glycine receptor alpha 3 / O75311*ENSMUSG0000003825782
Glra4 / Q61603 / Glycine receptor subunit alpha-4 / Q5JXX5* / glycine receptor alpha 4*ENSMUSG0000001859574
Glra2 / Q7TNC8 / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA. / P23416* / glycine receptor alpha 2*ENSMUSG0000001858974
Glrb / P48168 / Glycine receptor subunit beta / P48167* / glycine receptor beta*ENSMUSG0000002802044
Gabrb1 / P50571 / Gamma-aminobutyric acid receptor subunit beta-1 / P18505* / gamma-aminobutyric acid type A receptor beta1 subunit*ENSMUSG0000002921235
Gabrb3 / P63080 / Gamma-aminobutyric acid receptor subunit beta-3 / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*ENSMUSG0000003367635
Gabrb2 / P63137 / Gamma-aminobutyric acid receptor subunit beta-2 / P47870* / gamma-aminobutyric acid type A receptor beta2 subunit*ENSMUSG0000000765335
Gabrd / P22933 / Gamma-aminobutyric acid receptor subunit delta / O14764* / gamma-aminobutyric acid type A receptor delta subunit*ENSMUSG0000002905432
Gabrq / Q9JLF1 / Gamma-aminobutyric acid receptor subunit theta / Q9UN88* / gamma-aminobutyric acid type A receptor theta subunit*ENSMUSG0000003134432
Gabrr1 / P56475 / Gamma-aminobutyric acid receptor subunit rho-1 / P24046* / gamma-aminobutyric acid type A receptor rho1 subunit*ENSMUSG0000002828032
Gabrr2 / P56476 / Gamma-aminobutyric acid receptor subunit rho-2 / P28476* / gamma-aminobutyric acid type A receptor rho2 subunit*ENSMUSG0000002326731
Gabrp / Q8QZW7 / Gamma-aminobutyric acid receptor subunit pi / O00591* / gamma-aminobutyric acid type A receptor pi subunit*ENSMUSG0000002015931
Gabrr3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*ENSMUSG0000007499131


Protein motifs (from Interpro)
Interpro ID Name
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR008127  Glycine receptor alpha
 IPR008128  Glycine receptor alpha1
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IMP
 biological_processGO:0001964 startle response IEA
 biological_processGO:0002087 regulation of respiratory gaseous exchange by neurological system process IMP
 biological_processGO:0006811 ion transport ISO
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0006821 chloride transport ISO
 biological_processGO:0006936 muscle contraction IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IMP
 biological_processGO:0007340 acrosome reaction IMP
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0007628 adult walking behavior IMP
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0043200 response to amino acid IBA
 biological_processGO:0043576 regulation of respiratory gaseous exchange IMP
 biological_processGO:0050884 neuromuscular process controlling posture IMP
 biological_processGO:0050905 neuromuscular process IMP
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0051970 negative regulation of transmission of nerve impulse IEA
 biological_processGO:0060012 synaptic transmission, glycinergic IEA
 biological_processGO:0060013 righting reflex IMP
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060080 inhibitory postsynaptic potential IMP
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0071294 cellular response to zinc ion IEA
 biological_processGO:0071361 cellular response to ethanol IEA
 biological_processGO:0097305 response to alcohol IMP
 biological_processGO:1902476 chloride transmembrane transport IEA
 biological_processGO:2000344 positive regulation of acrosome reaction IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IDA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IDA
 cellular_componentGO:0060077 inhibitory synapse IDA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016594 glycine binding ISS
 molecular_functionGO:0016933 extracellularly glycine-gated ion channel activity IEA
 molecular_functionGO:0016934 extracellularly glycine-gated chloride channel activity ISS
 molecular_functionGO:0022824 transmitter-gated ion channel activity IEA
 molecular_functionGO:0030977 taurine binding IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neurotransmitter receptors and postsynaptic signal transmission


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

Allelic Composition: Glra1spd/Glra1+
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0000692 small spleen "decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

 MP:0000743 muscle spasms "muscular twitching, cramps and seizures ; frequently associated with calcium deficiency, hypoparathyroidism, vitamin D deficiency or alkalosis " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

Allelic Composition: Glra1spd-ot/Glra1spd-ot
Genetic Background: C57BL/6J-Glra1spd-ot Mpzl3rc

Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

Allelic Composition: Glra1cincinnati/Glra1cincinnati
Genetic Background: B6.129S6-Glra1cincinnati

Allelic Composition: Glra1tm1.1Geh/Glra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Glra1tm2.1Geh/Glra1tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

Allelic Composition: Glra1tm1.1Geh/Glra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Glra1tm2.1Geh/Glra1tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Ikbkaptm1Id/Ikbkaptm1.1Id,Tg(IKBKAP*)#Sasl/0
Genetic Background: involves: 129S1/Sv * C57BL/6N

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Glra1tm2.1Geh/Glra1tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Glra1tm1.1Geh/Glra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Glra1tm2.1Geh/Glra1tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

 MP:0001407 short stride length "reduced average distance between steps" [J:34193]
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Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

 MP:0001486 abnormal startle reflex "abberant threshold or reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Krt71Mhdarco12/Krt71+
Genetic Background: C3HeB/FeJ-Krt71Mhdarco12

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Glra1tm1Rah/Glra1tm1Rah
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: involves: A/HeJ

Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

Allelic Composition: Glra1tm1.1Geh/Glra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Glra1tm2.1Geh/Glra1tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

 MP:0001504 abnormal posture "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
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Allelic Composition: Gja8Lop10/Gja8Lop10
Genetic Background: C;AK-Gja8Lop10/J

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Glra1tm1Rah/Glra1tm1Rah
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
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Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

Allelic Composition: Glra1cincinnati/Glra1cincinnati
Genetic Background: B6.129S6-Glra1cincinnati

 MP:0001783 decreased white fat amount "reduced quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Glra1tm1Rah/Glra1tm1Rah
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

 MP:0002272 abnormal nervous system electrophysiology "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0002862 altered righting response "altered ability or changed amount of time needed to recover from supine position" [hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Glra1tm1.1Geh/Glra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Glra1tm2.1Geh/Glra1tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
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Allelic Composition: Glra1tm1.1Geh/Glra1tm1.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

Allelic Composition: Glra1tm2.1Geh/Glra1tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL

 MP:0002945 abnormal inhibitory postsynaptic currents "defect in the size or duration of currents detected in postsynaptic cells when an inhibitory impulse arrives at the synapse causing hyperpolarization" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

 MP:0003463 abnormal single cell response "altered values from controls obtained upon extra- or intracellular recordings from single cells" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

 MP:0003484 abnormal channel response "anomalies in the electrophysiological recordings from ion channels" [Nmice:Neuromice Consortium Submission]
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Allelic Composition: Glra1tm1Rah/Glra1tm1Rah
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003644 thymus atrophy "wasting of the thymus resulting in reduced size " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

 MP:0003997 tonic-clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Ikbkaptm1Id/Ikbkaptm1.1Id,Tg(IKBKAP*)#Sasl/0
Genetic Background: involves: 129S1/Sv * C57BL/6N

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

 MP:0004143 hypertonia "increased muscle tone" [hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

 MP:0004542 impaired acrosome reaction "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Glra1spd/Glra1spd
Genetic Background: B6C3Fe a/a-Glra1spd/J

Allelic Composition: Glra1spd/Glra1+
Genetic Background: B6C3Fe a/a-Glra1spd/J

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Glra1cincinnati/Glra1cincinnati
Genetic Background: B6.129S6-Glra1cincinnati

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

 MP:0005572 abnormal breathing frequency "deviation from the normal number of breaths in a given period of time" [RGD:Rat Genome Database submission]
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Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0005604 hyperekplexia "disorder characterized by pathologic startle responses, protective reactions to unanticipated, potentially threatening, stimuli of any type, particularly auditory" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Glra1spd/Glra1spd
Genetic Background: involves: A/HeJ

 MP:0008948 decreased neuron number "fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]
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Allelic Composition: Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou
Genetic Background: involves: 129S2/SvPas * C57BL/6 * DBA/2

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Glra1tm1Rah/Glra1tm1Rah
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: Glra1cincinnati/Glra1cincinnati
Genetic Background: B6.129S6-Glra1cincinnati

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Glra1spd-ot/Glra1spd-ot
Genetic Background: C57BL/6J-Glra1spd-ot Mpzl3rc

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Ikbkaptm1Id/Ikbkaptm1.1Id,Tg(IKBKAP*)#Sasl/0
Genetic Background: involves: 129S1/Sv * C57BL/6N

 MP:0012146 increased b wave amplitude "increase in the size (height or maximum displacement) of the b wave as measured in the electroretinogram" [MGI:csmith]
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Allelic Composition: Glra1tm1Betz/Glra1tm1Betz
Genetic Background: B6.129P2-Glra1tm1Betz

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028020 Glrb / P48168 / Glycine receptor subunit beta / P48167* / glycine receptor beta*  / complex






 

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