| MP:0000267 | abnormal cardiac development | "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0001622 | abnormal vasculogenesis | "aberrant process of the initial establishment of the vascular network " [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0002753 | dilated left ventricle | "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0002950 | abnormal neural crest cell migration | "defect in the dispersion of the transient and migratory group of cells that emerge from the dorsal region of the neural tube and migrate to many peripheral locations to form various tissues of the adult" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0003141 | cardiac fibrosis | "formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0003228 | abnormal sinus venosus | "malformation in the cavity at the caudal end of the embryonic cardiac tube in which the veins from the intra- and extraembryonic circulatory arcs unite; in the adult this becomes the portion of the right atrium known as the sinus of the vena cava" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0003229 | abnormal vitelline vasculature | "malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0003921 | abnormal left ventricle morphology | "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0004215 | abnormal myocardial fiber physiology | "anomaly in the function of the multinucleated muscle cells of the heart" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0004485 | increased response of heart to induced stress | "increase in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0005140 | decreased cardiac muscle contractility | "inability or reduced ability of the heart muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0005630 | increased lung weight | "greater than the normal state of the physical heaviness of the lung" [RGD:Rat Genome Database submission] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0006138 | congestive heart failure | "the heart is unable to adequately pump blood throughout the body" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Slc13a5tm1.2Helf/Slc13a5+
Genetic Background: B6.Cg-Slc13a5tm1.2Helf
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| MP:0006207 | embryonic lethality during organogenesis | "death anytime after embryo turning but before the completion of organogenesis (E9 to less than E14)" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Clcn3tm1.1Jrhm/Clcn3tm1.1Jrhm,Tg(Myh6-tTA)6Smbf/0,Tg(tetO-cre)3Jig/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
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| MP:0009395 | persistence of primitive erythrocytes | "presence of increased numbers of nucleated red blood cells at stages when these cells are normally replaced by mature, enucleated, red blood cells" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0011092 | complete embryonic lethality | "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Cnbpm1Hrb/Cnbp+
Genetic Background: B6.129S4-Cnbpm1Hrb
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| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Il2rgtm1Cgn/Y
Genetic Background: involves: 129 * CB20
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| MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Kmt2atm2(MLLT3)Thr/Kmt2atm2(MLLT3)Thr
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB
Allelic Composition: Capns1tm2.1Pag/Capns1tm2.1Pag
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
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