ENSMUSG00000078144


Mus musculus

Features
Gene ID: ENSMUSG00000078144
  
Biological name :Capns2
  
Synonyms : Calpain small subunit 2 / Capns2 / Q9D7J7
  
Possible biological names infered from orthology : Q96L46
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C5
Gene start: 92901407
Gene end: 92902411
  
Corresponding Affymetrix probe sets: 10573954 (MoGene1.0st)   1429067_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100553
NCBI entrez gene - 69543     See in Manteia.
MGI - MGI:1916793
RefSeq - NM_027112
RefSeq Peptide - NP_081388
swissprot - Q9D7J7
Ensembl - ENSMUSG00000078144
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capns1aENSDARG00000035329Danio rerio
 capns1bENSDARG00000013804Danio rerio
 CAPNS2ENSGALG00000045050Gallus gallus
 CAPNS2ENSG00000256812Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Capns1 / calpain small subunit 1 / P04632*ENSMUSG0000000179468
Gca / Q8VC88 / Grancalcin / P28676*ENSMUSG0000002689327
Sri / Q6P069 / Sorcin / P30626*ENSMUSG0000000316125
Pef1 / Q8BFY6 / Peflin / Q9UBV8* / penta-EF-hand domain containing 1*ENSMUSG0000002877921
Pdcd6 / P12815 / Programmed cell death protein 6 / O75340* / programmed cell death 6*ENSMUSG0000002157619


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024942 Capn1 / O35350 / Calpain-1 catalytic subunit / P07384* / calpain 1*  / complex
 ENSMUSG00000026509 Capn2 / O08529 / Calpain-2 catalytic subunit / P17655* / calpain 2*  / complex
 ENSMUSG00000048895 Cdk5r1 / P61809 / Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 activator 1, p35 Cyclin-dependent kinase 5 activator 1, p25 / Q15078* / cyclin dependent kinase 5 regulator...  / reaction






 

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