ENSMUSG00000004105


Mus musculus

Features
Gene ID: ENSMUSG00000004105
  
Biological name :Angptl2
  
Synonyms : Angiopoietin-related protein 2 / Angptl2 / Q9R045
  
Possible biological names infered from orthology : angiopoietin like 2 / Q9UKU9
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 33216069
Gene end: 33247717
  
Corresponding Affymetrix probe sets: 10471555 (MoGene1.0st)   1421002_at (Mouse Genome 430 2.0 Array)   1431848_at (Mouse Genome 430 2.0 Array)   1446534_at (Mouse Genome 430 2.0 Array)   1450085_at (Mouse Genome 430 2.0 Array)   1455090_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142084
Ensembl peptide - ENSMUSP00000004208
NCBI entrez gene - 26360     See in Manteia.
MGI - MGI:1347002
RefSeq - NM_011923
RefSeq - XM_006498051
RefSeq Peptide - NP_036053
swissprot - A0A0A6YXQ1
swissprot - Q9R045
Ensembl - ENSMUSG00000004105
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01039096.1ENSDARG00000116302Danio rerio
 ANGPTL2ENSGALG00000000927Gallus gallus
 Q9UKU9ENSG00000136859Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q640P2 / Angptl1 / Angiopoietin-related protein 1 / O95841* / angiopoietin like 1*ENSMUSG0000003354458
Q8R0Z6 / Angptl6 / Angiopoietin-related protein 6 / Q8NI99* / angiopoietin like 6*ENSMUSG0000003874239
Angpt2 / O35608 / Angiopoietin-2 / O15123*ENSMUSG0000003146526
Angpt4 / Q9WVH6 / Angiopoietin-4 / Q9Y264*ENSMUSG0000002746026
A2AV25 / Fibcd1 / Fibrinogen C domain-containing protein 1 / Q8N539* / fibrinogen C domain containing 1*ENSMUSG0000002684125
Angpt1 / O08538 / Angiopoietin-1 / Q15389*ENSMUSG0000002230925
Fcnb / O70497 / Ficolin-2 / FCN1* / FCN2* / Q15485* / O00602* / ficolin 1*ENSMUSG0000002683524
Fcna / O70165 / Ficolin-1 ENSMUSG0000002693822
Fgl2 / P12804 / Fibroleukin / Q14314* / fibrinogen like 2*ENSMUSG0000003989920
Q8R1Q3 / Angptl7 / Angiopoietin-related protein 7 / O43827* / angiopoietin like 7*ENSMUSG0000002898920
Mfap4 / Q9D1H9 / Microfibril-associated glycoprotein 4 / P55083* / microfibril associated protein 4*ENSMUSG0000004243618


Protein motifs (from Interpro)
Interpro ID Name
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR020837  Fibrinogen, conserved site
 IPR036056  Fibrinogen-like, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: ApcMin/Apc+,Mom5129P2/OlaHsd/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002891 increased insulin sensitivity "greater ability to clear glucose from the bloodstream when given insulin than normal; can result in hypoglycemia" [RGD:Rat Genome Database submission]
Show

Allelic Composition: ApcMin/Apc+,Mom5129P2/OlaHsd/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0003799 impaired macrophage migration "defect in the ability of macrophages to move up a chemotactic gradient" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: ApcMin/Apc+,Mom5129P2/OlaHsd/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: ApcMin/Apc+,Mom5129P2/OlaHsd/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Mom5129P2/OlaHsd/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Mom5129P2/OlaHsd/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0010379 decreased respiratory quotient "reduction in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: ApcMin/Apc+,Mom5129P2/OlaHsd/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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