| MP:0000030 | abnormal tympanic ring morphology | "malformed bony ring at the ear canal to which the tympanic membrane is attached" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0000031 | abnormal cochlea morphology | "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0000060 | delayed bone ossification | "late onset of the formation of bone" [J:40203] |
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Allelic Composition: Vhltm1Bjg/Vhltm1Bjg
Genetic Background: Not Specified
|
| MP:0000063 | reduced bone density | "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0000077 | abnormal interparietal bone morphology | "malformed bone of the cranium; lies above and anterior to the occipital bone " [J:61509] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0000079 | abnormal basioccipital bone morphology | "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
|
| MP:0000085 | large anterior fontanelle | "enlarged diamond-shaped membranous interval at the junction of the coronal, sagittal and metopic sutures of the cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0000102 | abnormal nasal bone morphology | "malformed elongated rectangular bone that forms part of the nasal bridge" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0000106 | abnormal basisphenoid bone morphology | "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Elavl1tm1Dkon/Elavl1tm1Dkon,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Allelic Composition: Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0000128 | growth retardation of molars | "developmental delay of the growth of the molars" [J:17489] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Vhltm1Bjg/Vhltm1Bjg
Genetic Background: Not Specified
|
| MP:0000149 | abnormal scapula morphology | "malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049] |
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp4tm1Jfm/Bmp4tm1Jfm,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL
Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob,Bmpr1btm1Kml/Bmpr1btm1Kml
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0000153 | rib bifurcation | "forking or division of ribs, may be a result of partial rib fusions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0000154 | rib fusion | "appearance of one or more ribs as a single structure" [J:62022, J:62023] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Bmp4tm1Blh/Bmp4+,Bmp7tm1Kry/Bmp7+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0000155 | asymmetric rib attachment | "loss of bilateral symmetry in rib attachments to the vertebral column or to the sternum" [J:19212] |
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Allelic Composition: Bmp4tm1Blh/Bmp4+,Bmp7tm1Kry/Bmp7+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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| MP:0000157 | abnormal sternum morphology | "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212] |
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Allelic Composition: Bmp4tm1Blh/Bmp4+,Bmp7tm1Kry/Bmp7+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0000159 | abnormal xiphoid process | "malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0000163 | abnormal cartilage morphology | "anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Cpa3tm3(icre)Hrr/Cpa3+,Fgfr1tm1Upir/Fgfr1tm1Upir,Fgfr2tm1Dor/Fgfr2tm1Dor,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
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| MP:0000220 | increased monocyte count | "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: C57BL/6N-Asxl1tm1a(EUCOMM)Wtsi/Cnrm
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| MP:0000377 | abnormal hair follicle | "malformed invagination of the epidermis from which the hair shaft develops" [J:65031] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0000428 | abnormal craniofacial morphology | "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Elavl1tm1Dkon/Elavl1tm1Dkon,Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
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| MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0000455 | abnormal maxilla morphology | "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0000458 | abnormal mandible morphology | "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
Allelic Composition: Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0000527 | abnormal kidney development | "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Bmp7tm2Rob/Bmp7tm2Rob
Genetic Background: involves: 129S/SvEv
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| MP:0000536 | hydroureter | "distention of the ureter with urine, due to blockage from any cause" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:Cml, J:13044] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Bmp7tm2Rob/Bmp7tm2Rob
Genetic Background: involves: 129S/SvEv
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| MP:0000562 | polydactyly | "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Bmp4tm1Blh/Bmp4+,Bmp7tm1Kry/Bmp7+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0000572 | abnormal autopod morphology | "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bmpr1btm1Kml/Bmpr1btm1Kml,Gdf5bp-J/Gdf5bp-J
Genetic Background: involves: 129S/SvEv * A/J * C57BL/6J
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| MP:0000585 | kinked tail | "a sharp bend or zig-zag in the tail" [J:61295] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Vhltm1Bjg/Vhltm1Bjg
Genetic Background: Not Specified
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| MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
Show
Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Fxr1tm1.2Dln/Fxr1tm1.2Dln
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Fxr1tm1.2Dln/Fxr1tm1.2Dln
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0001286 | abnormal eye development | "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840] |
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Allelic Composition: Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
Genetic Background: B6.Cg-Bmp7tm1.1Dgra
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| MP:0001292 | abnormal lens vesicle development | "malformation or abnormal patterning of the lens vesicle of the eye" [J:49424] |
Show
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0001293 | anophthalmia | "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0001297 | microphthalmia | "reduced average size of the eyes" [J:18048] |
Show
Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7tm2Rob/Bmp7tm4(Bmp4)Rob
Genetic Background: involves: 129S/SvEv
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Vhltm1Bjg/Vhltm1Bjg
Genetic Background: Not Specified
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| MP:0001676 | abnormal apical ectodermal ridge | "malformation of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Vhltm1Bjg/Vhltm1Bjg
Genetic Background: Not Specified
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| MP:0002098 | abnormal vibrissae morphology | "irregular or unusual structure, appearance, or alignment of the vibrissae" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0002100 | abnormal tooth morphology | "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0002110 | abnormal digit morphology | "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Fxr1tm1.2Dln/Fxr1tm1.2Dln
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Bmp4tm1Blh/Bmp4+,Bmp7tm1Kry/Bmp7+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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| MP:0002114 | abnormal axial skeleton morphology | "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
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| MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm2Rob/Bmp7tm4(Bmp4)Rob
Genetic Background: involves: 129S/SvEv
Allelic Composition: Bmp7tm3(Bmp7)Rob/Bmp7tm2Rob
Genetic Background: involves: 129S/SvEv
Allelic Composition: Bmp2tm1Cjt/Bmp2+,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Bmp2tm1Cjt/Bmp2+,Bmp7tm1Rob/Bmp7+,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
Genetic Background: B6.Cg-Bmp7tm1.1Dgra
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| MP:0002187 | abnormal fibula morphology | "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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| MP:0002258 | abnormal cricoid cartilage morphology | "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0002260 | abnormal thyroid cartilage morphology | "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0002428 | abnormal semicircular canal | "anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0002500 | granulomatous inflammation | "chronic inflammation resulting from the failure of the acute inflammatory response and persistance of the injurious agent; characterized by a central area of marcophages, often fused into giant cells, and surrounded by T cells " [Pathology:ISBN 0-397-51047-0, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6
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| MP:0002543 | brachyphalangia | "abnormally short phalanges" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob,Bmpr1btm1Kml/Bmpr1btm1Kml
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0002590 | increased mean corpuscular volume | "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: C57BL/6N-Asxl1tm1a(EUCOMM)Wtsi/Cnrm
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| MP:0002631 | abnormal epididymis morphology | "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6
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| MP:0002689 | abnormal molar morphology | "structural defect of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [il:Ira Lu , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0002875 | decreased erythrocyte count | "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Asxl1tm1a(EUCOMM)Wtsi/Asxl1+
Genetic Background: C57BL/6N-Asxl1tm1a(EUCOMM)Wtsi/Cnrm
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| MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Cpa3tm3(icre)Hrr/Cpa3+,Fgfr1tm1Upir/Fgfr1tm1Upir,Fgfr2tm1Dor/Fgfr2tm1Dor,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
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| MP:0002933 | joint inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the joints" [RGD:Rat Genome Database submission] |
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Allelic Composition: Cpa3tm3(icre)Hrr/Cpa3+,Fgfr1tm1Upir/Fgfr1tm1Upir,Fgfr2tm1Dor/Fgfr2tm1Dor,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
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| MP:0002989 | small kidney | "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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| MP:0003050 | abnormal sacral vertebrae morphology | "malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0003056 | abnormal hyoid bone | "anomalous structure of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, hdene:Howard Dene, Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0003078 | aphakia | "absence of the crystalline lens of the eye" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0003138 | absent tympanic ring | "missing the bony ring at the ear canal to which the tympanic membrane is attached" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:46972] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0003154 | abnormal soft palate | "abnormality in the musculomembranous fold that partly separates the mouth and pharynx, located behind the hard palate" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0003235 | abnormal alisphenoid bone morphology | "malformation in either of the broad curved winglike expanses on each side of the sphenoid bone" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93183, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0003345 | decreased number of ribs | "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0003445 | sirenomelia | "fusion of the posterior limbs often with partial or complete fusion of the autopods" [J:67375] |
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Allelic Composition: Pcdh15av/Pcdh15av
Genetic Background: involves: K
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| MP:0003446 | renal hypoplasia | "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0003560 | osteoarthritis | "a type of arthritis that is caused by the breakdown and eventual loss of the cartilage of one or more joints" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95374] |
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Allelic Composition: Cpa3tm3(icre)Hrr/Cpa3+,Fgfr1tm1Upir/Fgfr1tm1Upir,Fgfr2tm1Dor/Fgfr2tm1Dor,Tg(KRT5-cre)5132Jlj/0
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
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| MP:0003670 | dilated glomerular capsule | "an expansion in volume of the expanded beginning of a nephron that contains the glomerulus" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:91499] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0003675 | kidney cysts | "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Bmp7tm2Rob/Bmp7tm2Rob
Genetic Background: involves: 129S/SvEv
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| MP:0003756 | abnormal hard palate | "abnormality in the anterior part of the palate that is supported by and includes the palatal extensions of the maxillary and palatine bones " [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0003935 | abnormal craniofacial development | "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0004083 | polysyndactyly | "greater than 5 digits present on an autopod with interdigital webbing also present" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Usf1tm1Svl/Usf1+,Usf2tm1Svl/Usf2+
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6J
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| MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0004351 | short humerus | "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob,Bmpr1btm1Kml/Bmpr1btm1Kml
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0004355 | short radius | "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob,Bmpr1btm1Kml/Bmpr1btm1Kml
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob,Bmpr1btm1Kml/Bmpr1btm1Kml
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0004384 | small interparietal bone | "reduced size of the bone of the cranium that lies above and anterior to the occipital bone in some mammals" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0004423 | abnormal squamosal bone morphology | "any structural anomaly of the thin, platelike part of the temporal bone" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0004456 | small pterygoid bone | "reduced size of the bone region which corresponds to the inner plate of the pterygoid process of the mammalian skull" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0004458 | absent alisphenoid bone | "absence of the broad curved wing like expanses on each side of the sphenoid bone in adults; may exist independently in the young" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0004459 | small alisphenoid bone | "reduced size of either of the broad curved wing like expanses on each side of the sphenoid bone in adults; may exist independently in the young" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0004462 | small basisphenoid bone | "reduced size of part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0004463 | basisphenoid bone foramen | "the presence of one or more holes in part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0004467 | absent zygomatic bone | "absence of the quadrilateral bone that forms the prominence of the cheek" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0004468 | small zygomatic bone | "reduced size of the quadrilateral bone that forms the prominence of the cheek" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0004470 | small nasal bone | "reduced size of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0004505 | decreased renal glomerulus number | "reduced number of the capillary loops of the kidney that normally function as a filtration unit" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
|
| MP:0004538 | abnormal maxillary shelf | "any structural anomaly of the outgrowth of the maxilla that normally fuses with palatine shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
|
| MP:0004539 | absent maxilla | "missing the upper bony framework of the mouth where the superior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0004574 | broad limb buds | "increased anterior-posterior width of the mesenchymal outgrowth on the lateral trunk of the embryo that develops into the limbs" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
|
| MP:0004595 | abnormal mandibular condyloid process morphology | "any structural anomaly of the round bump of bone and constricted neck portion that arises from the upper surface of the mandibular ramus (perpendicular portion) and articulates with the articular disk of the temporomandibular joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0004596 | abnormal mandibular angle morphology | "any structural anomaly of the portion of the mandible where the body of the mandible (horizontal portion) and the rami (perpendicular portions) meet; these normally unite nearly at right angles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0004612 | fusion of vertebral bodies | "improper union of the main cylindrical portion of adjacent vertebra ventral to the vertebral canal" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
|
| MP:0004624 | abnormal thoracic cage | "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp4tm1Blh/Bmp4+,Bmp7tm1Kry/Bmp7+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
|
| MP:0004634 | short metacarpal bones | "reduced length of the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob,Bmpr1btm1Kml/Bmpr1btm1Kml
Genetic Background: involves: 129S/SvEv * C57BL/6J
|
| MP:0004647 | decreased lumbar vertebrae number | "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
|
| MP:0004678 | split xiphoid process | "the appearance of an abnormal division of the posterior tip of the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp4tm1Blh/Bmp4+,Bmp7tm1Kry/Bmp7+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
|
| MP:0004679 | xiphoid process foramen | "the appearance of a hole or holes in the posterior tip of the sternum" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
|
| MP:0004726 | abnormal nasal capsule morphology | "any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
|
| MP:0004757 | abnormal distal convoluted tubule morphology | "any structural anomaly of the convoluted portion of the duct system of the nephron between the ascending portion of the loop of Henle and the collecting duct system in the kidney cortex; it is partly responsible for the regulation of potassium, sodium, calcium, and pH through the endocrine system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
|
| MP:0004790 | absent upper incisors | "missing the upper pair of long pointed teeth that are the most anterior and prominent in the jaw" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
|
| MP:0004852 | decreased testis weight | "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
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| MP:0004899 | absent squamosal bone | "absence of the thin, plate-like part of the temporal bone" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0004911 | absent mandibular condyloid process | "absence of the round bump of bone and constricted neck portion that arises from the upper surface of the mandibular ramus (perpendicular portion) and articulates with the articular disk of the temporomandibular joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0004912 | absent mandibular coronoid process | "absence of the thin, flattened, triangular eminence that arises from the upper surface of the mandibular ramus (perpendicular portion)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0004913 | absent mandibular angle | "absence of the portion of the mandible where the body of the mandible (horizontal portion) and the rami (perpendicular portions) meet; these normally unite nearly at right angles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp2tm1Jfm/Bmp2tm1Jfm,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
|
| MP:0004934 | epididymis epithelium degeneration | "pathological deterioration of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6
|
| MP:0004935 | epididymis degeneration | "pathological deterioration of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6
|
| MP:0005103 | abnormal retinal pigmentation | "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0005105 | abnormal middle ear ossicle morphology | "anomalous structure or development of the three small bones of the middle ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0005176 | eyelids fail to open | "eyes remain shut throughout life" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0005201 | abnormal retinal pigment epithelium morphology | "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob,Bmpr1btm1Kml/Bmpr1btm1Kml
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
|
| MP:0005325 | abnormal glomerulus | "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
|
| MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0005548 | retinal pigment epithelium atrophy | "wasting or decreased size of the epithelial layer of the retina composed of cells containing pigment granules " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
|
| MP:0006020 | reduced size of tympanic ring | "smaller than average tympanic ring" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0006362 | abnormal male germ cell morphology | "any structural anomaly of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss * C57BL/6
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| MP:0006400 | decreased molar number | "reduction in the number of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0008146 | asymmetric rib-sternum attachment | "loss of bilateral symmetry in rib attachments to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0008148 | abnormal rib-sternum attachment | "any anomaly in the in the normal joining of the ribs to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
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| MP:0008528 | polycystic kidney | "the development of innumerable cysts in the kidneys filled with fluid replacing much of the mass of the kidneys leading to reduction in kidney function and frequently kidney failure" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0009003 | abnormal vibrissa number | "any anomaly in the number of the stiff hairs projecting from the face around the nose of most mammals which act as touch receptors" [MESH:A13.950, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0009052 | anal stenosis | "abnormal narrowing or constriction of the anal orifice" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp4tm4Blh/Bmp4+,Bmp7tm1.1Dgra/Bmp7tm1.1Dgra,Hoxa3tm1(cre)Moon/Hoxa3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac
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| MP:0009250 | abnormal appendicular skeleton morphology | "any structural anomaly of the bones of the limbs, shoulder and pelvic girdles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Bmp2tm1Cjt/Bmp2tm1Cjt,Bmp7tm1Rob/Bmp7tm1Rob,Tg(Prrx1-cre)1Cjt/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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| MP:0009252 | absent urinary bladder | "absence of the inflatable musculomembranous bag for holding urine" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp4tm4Blh/Bmp4+,Bmp7tm1.1Dgra/Bmp7tm1.1Dgra,Hoxa3tm1(cre)Moon/Hoxa3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac
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| MP:0009674 | decreased birth weight | "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0009883 | palatal shelf hypoplasia | "reduced size of the palatal projections from the inner part of the maxillary processes that fuse to form the secondary palate, often due to reduced cell number" [PMID:16680722] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0009888 | palatal shelves fail to meet at midline | "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0010688 | hair follicle outer rooth sheath hyperplasia | "overdevelopment or increased size, usually due to a increased number of cells, outermost layer of the hair follicle that merges proximally with the basal layer of the interfollicular epidermis and distally with the hair bulb" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0010985 | abnormal kidney mesenchyme morphology | "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing kidney" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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| MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Bmp7tm1Rob/Bmp7+,Bmp8atm1Blh/Bmp8atm1Blh
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * Black Swiss
Allelic Composition: Bmp7tm1Rob/Bmp7tm1Rob
Genetic Background: either: (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)
Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0011090 | partial perinatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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| MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Dstdt-32J/Dstdt-32J
Genetic Background: involves: 129S/Sv * 129S2/SvPas
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| MP:0011100 | complete preweaning lethality | "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0011290 | decreased nephron number | "reduction in the total number of filtering units of the kidney" [MGI:anna] |
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Allelic Composition: Bmp7Tg(BCL2)114Cro/Bmp7Tg(BCL2)114Cro
Genetic Background: involves: C3H/HeJ * C57BL/6
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| MP:0011387 | absent metanephric mesenchyme | "absence of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing metanephros; normally, interactions between the ureteric bud and the metanephric mesenchyme lead to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:anna] |
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Allelic Composition: Bmp7tm1Kry/Bmp7tm1Kry
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0011846 | decreased kidney collecting duct number | "smaller than expected number of the kidney ducts that collect urine from the distal convoluted tubules, merge and become larger as they descend from the renal cortex into the medulla, and respond to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance" [MGI:anna] |
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Allelic Composition: Bmp7tm6(cre)Rob/Bmp7+,Smad4tm1Rob/Smad4tm1.1Rob
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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| MP:0012173 | short rostral-caudal axis | "length reduction or truncation of the axis that runs from the head to the tail of the body" [MGI:anna] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * BALB/cJ * C57BL/6J * C57BL/6NTac
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| MP:0030026 | small Meckel s cartilage | "reduced size of the cartilage bar in the mandibular arch that forms a temporary supporting structure in the embryonic mandible and gives rise to middle ear bones and sphenomandibular and anterior malleolar ligaments" [MGI:anna] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0030121 | small temporal bone squamous part | "reduced size of the anterosuperior portion of the temporal bone that is thin, scale-like, and translucent and forms part of the lateral wall of the cranial vault" [MGI:anna] |
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Allelic Composition: Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4+,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
Allelic Composition: Bmp2tm1Jfm/Bmp2+,Bmp4tm1Jfm/Bmp4tm1Jfm,Bmp7tm1Jfm/Bmp7tm1Jfm,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * CBA/J
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| MP:0030136 | abnormal lower incisor morphology | "any structural anomaly of the lower set of long teeth that are the most anterior and prominent in the jaw" [MGI:anna] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0030200 | abnormal nasal septum cartilage morphology | "any structural anomaly of the hyaline cartilage of the nasal septum that is somewhat quadrilateral in shape, thicker at its margins than at its center, and completes the separation between the nasal cavities" [https://en.wikipedia.org/wiki/Septal_nasal_cartilage, MGI:anna] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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| MP:0030319 | abnormal temporal bone petrous part morphology | "any structural anomaly of the dense, pyramid-shaped portion of the temporal bone that is wedged in at the base of the skull between the sphenoid and occipital bones; directed medially, forward, and a little upward, it presents a base, an apex, three surfaces, and three angles, and houses in its interior, the components of the inner ear; the petrous portion is among the most basal elements of the skull and forms part of the endocranium" [https://en.wikipedia.org/wiki/Petrous_part_of_the_temporal_bone] |
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Allelic Composition: Bmp7tm1.2Dgra/Bmp7tm1.2Dgra
Genetic Background: B6.Cg-Bmp7tm1.2Dgra
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