ENSMUSG00000020937


Mus musculus

Features
Gene ID: ENSMUSG00000020937
  
Biological name :Plcd3
  
Synonyms : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 / Plcd3 / Q8K2J0
  
Possible biological names infered from orthology : phospholipase C delta 3 / Q8N3E9
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E1
Gene start: 103070304
Gene end: 103101658
  
Corresponding Affymetrix probe sets: 10391837 (MoGene1.0st)   1431892_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099366
Ensembl peptide - ENSMUSP00000117455
NCBI entrez gene - 72469     See in Manteia.
MGI - MGI:107451
RefSeq - XM_017314789
RefSeq - NM_152813
RefSeq - XM_006534309
RefSeq - XM_006534310
RefSeq - XM_017314788
RefSeq - XM_006534308
RefSeq Peptide - NP_690026
swissprot - Q8K2J0
swissprot - F7AAE0
Ensembl - ENSMUSG00000020937
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A5D6R3ENSDARG00000052957Danio rerio
 plcd3bENSDARG00000079572Danio rerio
 PLCD3ENSGALG00000045212Gallus gallus
 PLCD3ENSG00000161714Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plcd1 / Q8R3B1 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 / P51178* / phospholipase C delta 1*ENSMUSG0000001066048
Plcd4 / Q8K3R3 / phospholipase C, delta 4 / Q9BRC7*ENSMUSG0000002617342
Plch2 / A2AP18 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 / O75038* / phospholipase C eta 2*ENSMUSG0000002905537
Plch1 / Q4KWH5 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 / Q4KWH8* / phospholipase C eta 1*ENSMUSG0000003683436
Plcl2 / Q8K394 / Inactive phospholipase C-like protein 2 / Q9UPR0* / phospholipase C like 2*ENSMUSG0000003891035
Plcl1 / Q3USB7 / Inactive phospholipase C-like protein 1 / Q15111* / phospholipase C like 1 (inactive)*ENSMUSG0000003834934
Plcb2 / A3KGF7 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 / Q00722* / phospholipase C beta 2*ENSMUSG0000004006130
Plcz1 / Q8K4D7 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 / Q86YW0* / phospholipase C zeta 1*ENSMUSG0000003023030
Plcb1 / Q9Z1B3 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 / Q9NQ66* / phospholipase C beta 1*ENSMUSG0000005117729
Plcb3 / P51432 / phospholipase C, beta 3 / Q01970*ENSMUSG0000002496029
Plcb4 / phospholipase C, beta 4 / Q15147*ENSMUSG0000003994329


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000909  Phosphatidylinositol-specific phospholipase C, X domain
 IPR001192  Phosphoinositide phospholipase C family
 IPR001711  Phospholipase C, phosphatidylinositol-specific, Y domain
 IPR001849  Pleckstrin homology domain
 IPR011992  EF-hand domain pair
 IPR011993  PH-like domain superfamily
 IPR017946  PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
 IPR028406  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IGI
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042127 regulation of cell proliferation IGI
 biological_processGO:0060716 labyrinthine layer blood vessel development IGI
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 molecular_functionGO:0004435 phosphatidylinositol phospholipase C activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP3 and IP4 in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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