ENSMUSG00000022738


Mus musculus

Features
Gene ID: ENSMUSG00000022738
  
Biological name :Gsc2
  
Synonyms : goosecoid homeobox 2 / Gsc2
  
Possible biological names infered from orthology : O15499
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 17913107
Gene end: 17915059
  
Corresponding Affymetrix probe sets: 10438256 (MoGene1.0st)   1454263_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000012279
NCBI entrez gene - 195333     See in Manteia.
MGI - MGI:892006
RefSeq - NM_029469
RefSeq Peptide - NP_083745
swissprot - A2RTU1
Ensembl - ENSMUSG00000022738
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GSC2ENSGALG00000044245Gallus gallus
 GSC2ENSG00000063515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gsc / Q02591 / Homeobox protein goosecoid / P56915* / goosecoid homeobox*ENSMUSG0000002109536
Mixl1 / Q9WUI0 / Homeobox protein MIXL1 / Q9H2W2* / Mix paired-like homeobox*ENSMUSG0000002649724
Pitx2 / P97474 / paired-like homeodomain transcription factor 2 / Q99697* / paired like homeodomain 2*ENSMUSG0000002802323
Prop1 / P97458 / Homeobox protein prophet of Pit-1 / O75360* / PROP paired-like homeobox 1*ENSMUSG0000004454223
Dmbx1 / Q91ZK4 / Diencephalon/mesencephalon homeobox protein 1 / Q8NFW5* / diencephalon/mesencephalon homeobox 1*ENSMUSG0000002870723
Pitx1 / P70314 / paired-like homeodomain transcription factor 1 / P78337* / paired like homeodomain 1*ENSMUSG0000002150622
Pitx3 / O35160 / Pituitary homeobox 3 / O75364* / paired like homeodomain 3*ENSMUSG0000002522922
Prrx2 / paired related homeobox 2 / Q99811*ENSMUSG0000003947621
Otx2 / orthodenticle homeobox 2 / P32243*ENSMUSG0000002184820
Prrx1 / P63013 / Paired mesoderm homeobox protein 1 / P54821* / paired related homeobox 1*ENSMUSG0000002658620
Crx / O54751 / Cone-rod homeobox protein / O43186* / cone-rod homeobox*ENSMUSG0000004157820
Otx1 / P80205 / Homeobox protein OTX1 / P32242* / orthodenticle homeobox 1*ENSMUSG0000000591720


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Myo6sv-2J/Myo6sv-2J
Genetic Background: B6.Cg-Myo6sv-2J/J

Allelic Composition: Gsc2tm1Bhr/Gsc2tm1Bhr
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr