ENSMUSG00000023033


Mus musculus

Features
Gene ID: ENSMUSG00000023033
  
Biological name :Scn8a
  
Synonyms : Scn8a / sodium channel, voltage-gated, type VIII, alpha
  
Possible biological names infered from orthology : Q9UQD0 / sodium voltage-gated channel alpha subunit 8
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: F1
Gene start: 100869858
Gene end: 101045938
  
Corresponding Affymetrix probe sets: 10426955 (MoGene1.0st)   1423515_at (Mouse Genome 430 2.0 Array)   1439889_at (Mouse Genome 430 2.0 Array)   1442208_at (Mouse Genome 430 2.0 Array)   1448514_at (Mouse Genome 430 2.0 Array)   1451894_a_at (Mouse Genome 430 2.0 Array)   1457412_at (Mouse Genome 430 2.0 Array)   1458693_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144173
Ensembl peptide - ENSMUSP00000144582
Ensembl peptide - ENSMUSP00000144501
Ensembl peptide - ENSMUSP00000144371
Ensembl peptide - ENSMUSP00000144232
Ensembl peptide - ENSMUSP00000144223
Ensembl peptide - ENSMUSP00000080842
Ensembl peptide - ENSMUSP00000093912
Ensembl peptide - ENSMUSP00000104536
Ensembl peptide - ENSMUSP00000104537
Ensembl peptide - ENSMUSP00000104538
Ensembl peptide - ENSMUSP00000143876
Ensembl peptide - ENSMUSP00000143879
Ensembl peptide - ENSMUSP00000143898
Ensembl peptide - ENSMUSP00000144013
NCBI entrez gene - 20273     See in Manteia.
MGI - MGI:103169
RefSeq - XM_006520655
RefSeq - XM_017316518
RefSeq - XM_017316517
RefSeq - XM_017316516
RefSeq - XM_017316515
RefSeq - XM_017316514
RefSeq - XM_017316513
RefSeq - NM_001077499
RefSeq - NM_011323
RefSeq - XM_017316519
RefSeq - XM_017316512
RefSeq - XM_006520651
RefSeq - XM_006520656
RefSeq Peptide - NP_035453
RefSeq Peptide - NP_001070967
swissprot - Q4KL32
swissprot - A0A0J9YUW5
swissprot - F7D6K4
swissprot - F7D6J5
swissprot - F6U329
swissprot - A0A0J9YTW2
swissprot - A0A0J9YTW4
swissprot - A0A0J9YUK3
swissprot - A0A0J9YUL0
Ensembl - ENSMUSG00000023033
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scn8aaENSDARG00000005775Danio rerio
 scn8abENSDARG00000018032Danio rerio
 SCN8AENSGALG00000043728Gallus gallus
 SCN8AENSG00000196876Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Scn1a / A2APX8 / Sodium channel protein type 1 subunit alpha / P35498* / sodium voltage-gated channel alpha subunit 1*ENSMUSG0000006432977
Scn2a / sodium channel, voltage-gated, type II, alpha / Q99250* / sodium voltage-gated channel alpha subunit 2*ENSMUSG0000007531876
Scn3a / sodium channel, voltage-gated, type III, alpha / Q9NY46* / sodium voltage-gated channel alpha subunit 3*ENSMUSG0000005718274
Scn9a / Q62205 / Sodium channel protein type 9 subunit alpha / Q15858* / sodium voltage-gated channel alpha subunit 9*ENSMUSG0000007531671
Scn5a / Q9JJV9 / Sodium channel protein type 5 subunit alpha / Q14524* / sodium voltage-gated channel alpha subunit 5*ENSMUSG0000003251164
Scn4a / sodium channel, voltage-gated, type IV, alpha / P35499* / sodium voltage-gated channel alpha subunit 4*ENSMUSG0000000102763
Q6QIY3 / Scn10a / sodium channel, voltage-gated, type X, alpha / Q9Y5Y9* / sodium voltage-gated channel alpha subunit 10*ENSMUSG0000003453356
Q9R053 / Scn11a / Sodium channel protein type 11 subunit alpha / Q9UI33* / sodium voltage-gated channel alpha subunit 11*ENSMUSG0000003411546
Scn7a / sodium voltage-gated channel alpha subunit 7 / Q01118*ENSMUSG0000003481041
Cacna1h / voltage-dependent T-type calcium channel subunit alpha-1H isoform 2 / O95180* / calcium voltage-gated channel subunit alpha1 H*ENSMUSG0000002411225
Cacna1g / calcium channel, voltage-dependent, T type, alpha 1G subunit / O43497* / calcium voltage-gated channel subunit alpha1 G*ENSMUSG0000002086624
Cacna1i / calcium channel, voltage-dependent, alpha 1I subunit / Q9P0X4* / calcium voltage-gated channel subunit alpha1 I*ENSMUSG0000002241623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001696  Voltage gated sodium channel, alpha subunit
 IPR005821  Ion transport domain
 IPR008054  Voltage gated sodium channel, alpha-8 subunit
 IPR010526  Sodium ion transport-associated
 IPR024583  Voltage-gated Na+ ion channel, cytoplasmic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0001518 voltage-gated sodium channel complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IEA
 molecular_functionGO:0005272 sodium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000243 myoclonus "involuntary shock-like contractions, variable in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles; generally due to a central nervous system lesion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Grem1tm1Rmh/Grem1tm1Rmh
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Scn8aM1Btlr/Scn8aM1Btlr
Genetic Background: C57BL/6J-Scn8aM1Btlr

Allelic Composition: Scn8aM1Btlr/Scn8a+
Genetic Background: C57BL/6J-Scn8aM1Btlr

Allelic Composition: Scn8amed-J/Scn8amed-J
Genetic Background: involves: STOCK Krt71Ca

Allelic Composition: Scn8amed-jo/Scn8amed-jo
Genetic Background: DBA/2WyDi-Scn8amed-jo

Allelic Composition: Scn8anur14/Scn8anur14
Genetic Background: C57BL/6J-Scn8anur14

Allelic Composition: Scn8amed-TgA4Bs/Scn8anur14
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8am10J/Scn8am10J
Genetic Background: FVB/NJ-Scn8am10J/GrsrCx

Allelic Composition: Scn8am3Btlr/Scn8am3Btlr
Genetic Background: C57BL/6J-Scn8am3Btlr

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: BALB/cJ-Scn8a9J/GrsrJ

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J * STOCK Krt71Ca

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0000748 progressive muscle weakness "increasing loss of strength over time" [MGI:CLS, J:67994]
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Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0000749 muscle degeneration "pathological deterioration of muscle tissue, often accompanied by loss of function" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

 MP:0000751 myopathy "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]
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Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0000752 dystrophic muscle "progressive weakness and wasting of muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67994]
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Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

Allelic Composition: Scn8admu/Scn8amed
Genetic Background: involves: C3H * C3HeB/Fe * C57BL/6

 MP:0000753 paralysis "loss of power of voluntary movement in a muscle through injury or disease of its nerve supply" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn8am10J/Scn8am10J
Genetic Background: FVB/NJ-Scn8am10J/GrsrCx

Allelic Composition: Scn8am11J/Scn8am11J
Genetic Background: B6.Cg-Scn8am11J/GrsrJ

 MP:0000755 hindlimb paralysis "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

Allelic Composition: Scn8a4J/Scn8a4J
Genetic Background: C57BL/6J-Scn8a4J/J

Allelic Composition: Scn8a5J/Scn8a5J
Genetic Background: C57BL/6J-Scn8a5J/J

Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Scn8anur14/Scn8anur14
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn8atm1Mm/Scn8atm1Mm,Tg(Zp3-cre)3Mrt/?
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: C57BL/6 * FVB * SJL * STOCK Krt71Ca

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

Allelic Composition: Scn8admu/Scn8amed
Genetic Background: involves: C3H * C3HeB/Fe * C57BL/6

Allelic Composition: Scn8amed-TgA4Bs/Scn8amed-TgA4Bs
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Scn8anur14/Scn8anur14
Genetic Background: C57BL/6J-Scn8anur14

Allelic Composition: Scn8am2Btlr/Scn8am2Btlr
Genetic Background: C57BL/6J-Scn8am2Btlr

Allelic Composition: Scn8am11J/Scn8am11J
Genetic Background: B6.Cg-Scn8am11J/GrsrJ

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
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Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0000872 abnormal external granule cell layer "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0000876 Purkinje cell degeneration "a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854]
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Allelic Composition: Scn8amed-jo2J/Scn8amed-jo2J
Genetic Background: B6(129S7)-Scn8amed-jo2J/J

Allelic Composition: Scn8amed-jo/Scn8amed-jo
Genetic Background: DBA/2WyDi-Scn8amed-jo

 MP:0000880 decreased Purkinje cell number "fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302]
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Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0000921 demyelination "loss of the myelin sheath without loss of axons or fiber tracts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0000940 abnormal motor neuron innervation "misprojection or failure to bundle motor axons to an effector tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
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Allelic Composition: Cdkn2atm1Cjs/Cdkn2atm1Cjs,Pax7tm1Pgr/Pax7+,Tg(CKMM-tTA)A3Rhvh/0,Tg(tetO-Hgf,-EGFP)24Tcre/0
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * FVB

 MP:0000958 peripheral nervous system degeneration "a retrogressive impairment of function or destruction of the ganglia and peripheral nerves that lie outside the brain and spinal cord" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
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Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: GarsNmf249/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: C57BL/6J * FVB/NJ

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

Allelic Composition: Scn8amed-TgA4Bs/Scn8amed-TgA4Bs
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8am3Btlr/Scn8am3Btlr
Genetic Background: C57BL/6J-Scn8am3Btlr

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Atoh1tm2Hzo/Atoh1tm2Hzo
Genetic Background: Not Specified

Allelic Composition: Scn8a8J/Scn8a8J
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Scn8am10J/Scn8am10J
Genetic Background: FVB/NJ-Scn8am10J/GrsrCx

Allelic Composition: Scn8am11J/Scn8am11J
Genetic Background: B6.Cg-Scn8am11J/GrsrJ

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
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Allelic Composition: Celsr1tm1Fati/Celsr1tm1Fati,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a8J/Scn8a8J
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
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Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn8atm1Mm/Scn8atm1Mm,Tg(Zp3-cre)3Mrt/?
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

Allelic Composition: Scn8amed-J/Scn8amed-J
Genetic Background: involves: STOCK Krt71Ca

Allelic Composition: Scn8anur14/Scn8anur14
Genetic Background: C57BL/6J-Scn8anur14

Allelic Composition: Scn8amed-TgA4Bs/Scn8anur14
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Scn8am10J/Scn8am10J
Genetic Background: FVB/NJ-Scn8am10J/GrsrCx

Allelic Composition: Scn8am3Btlr/Scn8am3Btlr
Genetic Background: C57BL/6J-Scn8am3Btlr

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

Allelic Composition: Scn8am11J/Scn8am11J
Genetic Background: B6.Cg-Scn8am11J/GrsrJ

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Scn8amed-jo2J/Scn8amed-jo2J
Genetic Background: B6(129S7)-Scn8amed-jo2J/J

Allelic Composition: Scn8aM1Btlr/Scn8aM1Btlr
Genetic Background: C57BL/6J-Scn8aM1Btlr

Allelic Composition: Scn8aM1Btlr/Scn8a+
Genetic Background: C57BL/6J-Scn8aM1Btlr

Allelic Composition: Scn8amed-J/Scn8amed-J
Genetic Background: involves: STOCK Krt71Ca

Allelic Composition: Scn8a8J/Scn8a8J
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0001485 abnormal pinna reflex "failure to respond to an auditory stimulus by a characteristic ear twitch " [J:64900]
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Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/c

 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0001492 piloerection "the involuntary bristling of hairs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Celsr1tm1Fati/Celsr1tm1Fati,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0001504 abnormal posture "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
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Allelic Composition: Klk1b1tm1Pmtn/Klk1b1tm1Pmtn
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Klk1b1tm1Pmtn/Klk1b1tm1Pmtn
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Scn8amed-TgA4Bs/Scn8amed-TgA4Bs
Genetic Background: involves: C3H * C57BL/6J

 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: BALB/cJ-Scn8a9J/GrsrJ

 MP:0001524 impaired limb coordination "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]
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Allelic Composition: Scn8amed-jo/Scn8amed-jo
Genetic Background: DBA/2WyDi-Scn8amed-jo

 MP:0001525 impaired balance "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]
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Allelic Composition: Scn8amed-TgA4Bs/Scn8amed-TgA4Bs
Genetic Background: involves: C3H * C57BL/6J

 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Scn8a5J/Scn8a5J
Genetic Background: C57BL/6J-Scn8a5J/J

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

 MP:0001961 abnormal reflex "anomalies in an involuntary response to a peripheral stimulus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Stat4ity14/Stat4ity14
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Zdhhc8tm1Kara/Zdhhc8+
Genetic Background: Not Specified

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1m1R/Scnm1m1R
Genetic Background: involves: C57BL/6 * STOCK Krt71Ca

Allelic Composition: Scn8admu/Scn8amed
Genetic Background: involves: C3H * C3HeB/Fe * C57BL/6

Allelic Composition: Scn8a8J/Scn8a8J
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Scn8amed-TgA4Bs/Scn8anur14
Genetic Background: involves: C3H * C57BL/6J

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atoh1tm2Hzo/Atoh1tm2Hzo
Genetic Background: Not Specified

Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn8atm1Mm/Scn8atm1Mm,Tg(Zp3-cre)3Mrt/?
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: C57BL/6 * FVB * SJL * STOCK Krt71Ca

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J * STOCK Krt71Ca

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

Allelic Composition: Scn8amed-TgA4Bs/Scn8amed-TgA4Bs
Genetic Background: involves: C3H * C57BL/6J

Allelic Composition: Scn8a8J/Scn8a8J
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Scn8anur14/Scn8anur14
Genetic Background: C57BL/6J-Scn8anur14

Allelic Composition: Scn8aem1Mm/Scn8a+
Genetic Background: involves: C57BL/6J * SJL

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: BALB/cJ-Scn8a9J/GrsrJ

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0002106 abnormal muscle physiology "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Nodaltm2Rob/Nodaltm2Rob
Genetic Background: involves: 129S/SvEv * ICR

 MP:0002269 muscular atrophy "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

Allelic Composition: Scn8a6J/Scn8a6J
Genetic Background: C57BL/6J-Scn8a6J/J

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn8amed-TgA4Bs/Scn8amed-TgA4Bs
Genetic Background: involves: C3H * C57BL/6J

 MP:0002272 abnormal nervous system electrophysiology "anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Scn8amed-jo/Scn8amed-jo
Genetic Background: DBA/2WyDi-Scn8amed-jo

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Scn8amed-jo2J/Scn8amed-jo2J
Genetic Background: B6(129S7)-Scn8amed-jo2J/J

 MP:0002887 resistance to pharmacologically induced seizures "ability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:77284]
Show

Allelic Composition: Scn8amed-jo/Scn8amed-jo
Genetic Background: DBA/2WyDi-Scn8amed-jo

Allelic Composition: Scn8amed-jo/Scn8a+
Genetic Background: B6.D2-Scn8amed-jo/J

 MP:0002914 abnormal endplate potential activity "defect in the excitatory response of peripheral synapses to stimulation; these amplitudes are larger than central synapse potentials" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0003157 impaired muscle relaxation "reduced or absent ability of muscle to lengthen following contractions" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92510]
Show

Allelic Composition: Scn8am11J/Scn8am11J
Genetic Background: B6.Cg-Scn8am11J/GrsrJ

 MP:0003491 abnormal voluntary movement "anomalies in coordinated movements executed with a purpose and can be improved by learning and/or experience" [Nmice:Neuromice Consortium Submission]
Show

Allelic Composition: Scn8admu/Scn8amed
Genetic Background: involves: C3H * C3HeB/Fe * C57BL/6

 MP:0003852 skeletal muscle necrosis "pathological cell death in the skeletal muscle, usually due to irreversible damage" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

 MP:0003993 abnormal ventral spinal root morphology "any anomaly, deformity, or malformation of the anterior bundle of nerves emerging from the spinal cord to join with the posterior/dorsal nerve bundle at each spinal cord segment to form one of the 31 paired peripheral nerves" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0004142 abnormal muscle tone "anomaly in the resting tautness or laxity of a muscle, normally somewhere in the middle of the range between total contraction and total relaxation" [hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0004566 myocardial fiber degeneration "deterioration or destruction of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

 MP:0004709 cervical vertebrae degeneration "retrogressive pathologic change of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae and caudal to the skull" [MESH:National Library of Medicine_Medical Subject Headings, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8amed-jo2J/Scn8amed-jo2J
Genetic Background: B6(129S7)-Scn8amed-jo2J/J

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0004835 abnormal miniature endplate potential "defect in the size or duration of spontaneous currents detected in PNS postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aem1Mm/Scn8a+
Genetic Background: involves: C57BL/6J * SJL

 MP:0005294 abnormal heart ventricle morphology "structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

 MP:0005307 head tossing "compulsive flailing of the head in multiple directions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0005323 dystonia "impairment of muscle tone resulting in prolonged muscle contraction and involuntary movements such as repetitive movements, or twisting or writhing of the limbs" [J:84533]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn8amed-J/Scn8amed-J
Genetic Background: involves: STOCK Krt71Ca

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0005402 abnormal action potential "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0005403 abnormal nerve conduction "anomaly in the act of transmitting electricity along a single nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0005405 axon degeneration "retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Scn8amed-jo2J/Scn8amed-jo2J
Genetic Background: B6(129S7)-Scn8amed-jo2J/J

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Fgf8tm1.3Mrt/Fgf8tm1.4Mrt,Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sortm1Sor,Nkx2-5tm1(cre)Rjs/Nkx2-5+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S7/SvEvBrd

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6 * DBA/2J

Allelic Composition: Scn8amed/Scn8amed
Genetic Background: involves: C3HeB/FeJ * DBA/2J

Allelic Composition: Scn8amed-TgA4Bs/Scn8amed-TgA4Bs
Genetic Background: B6.Cg-Scn8amed-TgA4Bs

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1tm1.1Mm/Scnm1tm1.1Mm
Genetic Background: involves: C57BL/6 * FVB * SJL * STOCK Krt71Ca

Allelic Composition: Scn8amed-J/Scn8amed-J,Scnm1s/Scnm1s
Genetic Background: involves: C57BL/6J * STOCK Krt71Ca

 MP:0006113 abnormal heart septum morphology "abnormality in the wall between the atria or ventricles of the heart, usually incomplete closure" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

 MP:0006325 impaired hearing "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0006358 absent pinna reflex "complete failure to respond to an auditory stimulus by a characteristic ear twitch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kcnq2Nmf134/Kcnq2+,Scn1atm1.1Aesc/Scn1a+
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J

 MP:0008814 reduced nerve conduction velocity "decrease in the rate at which an eletrical impulse travels through a nerve" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

Allelic Composition: GarsC201R/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeJ * FVB/NJ

Allelic Composition: Scn8am10J/Scn8a+
Genetic Background: FVB/NJ-Scn8am10J/GrsrCx

Allelic Composition: GarsNmf249/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: C57BL/6J * FVB/NJ

 MP:0008840 abnormal spike wave discharge "anomaly in the characteristic epileptiformic electroencephalographic (EEG) activity detected in generalized absence epilepsy" [PMID:16725200]
Show

Allelic Composition: Scn8amed-jo/Scn8amed-jo
Genetic Background: DBA/2WyDi-Scn8amed-jo

Allelic Composition: Scn8amed-jo/Scn8a+
Genetic Background: B6.D2-Scn8amed-jo/J

Allelic Composition: Scn1atm1Wac/Scn1a+,Scn8amed-jo/Scn8a+
Genetic Background: involves: 129 * C57BL/6J * DBA/2WyDi * FVB/NJ

Allelic Composition: Scn8a8J/Scn8a8J
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

Allelic Composition: Scn8a8J/Scn8a+
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0008924 decreased granule neuron number "reduction in the number of the small neurons of the granule cell layer that send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"]
Show

Allelic Composition: Scn8a5J/Scn8a5J
Genetic Background: C57BL/6J-Scn8a5J/J

 MP:0009400 decreased skeletal muscle fiber size "decrease in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8a7J/Scn8a7J
Genetic Background: involves: BALB/cByJ * C57BL/6J

 MP:0009417 skeletal muscle atrophy "a wasting of skeletal muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: GarsNmf249/Gars+,Scn8am10J/Scn8a+
Genetic Background: involves: C57BL/6J * FVB/NJ

 MP:0009434 paraparesis "a weakness affecting lower limbs" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hps5ru2-r/Hps5ru2-r
Genetic Background: C57BL/10

 MP:0009779 enhanced behavioral response to anesthetic "increase or exceleration in the behavioral changes that follow exposure to a given amount of an anesthetizing agent" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0010492 abnormal atrium endocardium morphology "any structural anomaly of the thin serous membrane, primarily composed of endothelial tissue, that lines the interior of the atria" [MESH:A07.541.207]
Show

Allelic Composition: Scn8admu/Scn8admu
Genetic Background: involves: C3H * C57BL/6

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Scn8a5J/Scn8a5J
Genetic Background: C57BL/6J-Scn8a5J/J

Allelic Composition: Scn8anur14/Scn8anur14
Genetic Background: involves: C57BL/6J

Allelic Composition: Scn1atm1Wac/Scn1atm1Wac,Scn8amed-jo/Scn8a+
Genetic Background: involves: 129 * C57BL/6J * DBA/2WyDi * FVB/NJ

Allelic Composition: Scn8am10J/Scn8am10J
Genetic Background: FVB/NJ-Scn8am10J/GrsrCx

Allelic Composition: Scn8am11J/Scn8am11J
Genetic Background: B6.Cg-Scn8am11J/GrsrJ

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Scn8amed-jo2J/Scn8amed-jo2J
Genetic Background: B6(129S7)-Scn8amed-jo2J/J

Allelic Composition: Scn1atm1.1Aesc/Scn1atm1.1Aesc,Scn8amed-jo/Scn8a+
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * DBA/2WyDi

 MP:0011380 enlarged brain ventricle "increased size of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord" [MGI:smb]
Show

Allelic Composition: Scn8a5J/Scn8a5J
Genetic Background: C57BL/6J-Scn8a5J/J

 MP:0011966 abnormal auditory brainstem response waveform shape "any anomaly in the characteristic pattern of electrical activity recording of a series of vertex positive waves generated by neurons in the ascending auditory system, that can be recorded from scalp electrograms by using computer-averaged responses to short tone bursts" [MGI:csmith]
Show

Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Scn8amed-jo2J/Scn8amed-jo2J
Genetic Background: B6(129S7)-Scn8amed-jo2J/J

Allelic Composition: Scn8aClth/Scn8aClth
Genetic Background: involves: BALB/cAnN * C3H/HeH

Allelic Composition: Scn8aClth/Scn8a+
Genetic Background: involves: BALB/cAnN * C3H/HeH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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