ENSMUSG00000034810


Mus musculus

Features
Gene ID: ENSMUSG00000034810
  
Biological name :Scn7a
  
Synonyms : Scn7a / sodium voltage-gated channel alpha subunit 7
  
Possible biological names infered from orthology : Q01118
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C1.3
Gene start: 66673425
Gene end: 66784914
  
Corresponding Affymetrix probe sets: 10483353 (MoGene1.0st)   1427495_at (Mouse Genome 430 2.0 Array)   1436043_at (Mouse Genome 430 2.0 Array)   1436044_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042405
NCBI entrez gene - 20272     See in Manteia.
MGI - MGI:102965
RefSeq - NM_009135
RefSeq Peptide - NP_033161
swissprot - B1AYL1
Ensembl - ENSMUSG00000034810
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scn1aENSDARG00000086819Danio rerio
 scn1labENSDARG00000062744Danio rerio
 SCN9AENSGALG00000027793Gallus gallus
 SCN7AENSG00000136546Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Scn9a / Q62205 / Sodium channel protein type 9 subunit alpha / Q15858* / sodium voltage-gated channel alpha subunit 9*ENSMUSG0000007531653
Scn1a / A2APX8 / Sodium channel protein type 1 subunit alpha / P35498* / sodium voltage-gated channel alpha subunit 1*ENSMUSG0000006432951
Scn2a / sodium channel, voltage-gated, type II, alpha / Q99250* / sodium voltage-gated channel alpha subunit 2*ENSMUSG0000007531851
Scn3a / sodium channel, voltage-gated, type III, alpha / Q9NY46* / sodium voltage-gated channel alpha subunit 3*ENSMUSG0000005718250
Scn8a / sodium channel, voltage-gated, type VIII, alpha / Q9UQD0* / sodium voltage-gated channel alpha subunit 8*ENSMUSG0000002303348
Scn4a / sodium channel, voltage-gated, type IV, alpha / P35499* / sodium voltage-gated channel alpha subunit 4*ENSMUSG0000000102747
Scn5a / Q9JJV9 / Sodium channel protein type 5 subunit alpha / Q14524* / sodium voltage-gated channel alpha subunit 5*ENSMUSG0000003251145
Q6QIY3 / Scn10a / sodium channel, voltage-gated, type X, alpha / Q9Y5Y9* / sodium voltage-gated channel alpha subunit 10*ENSMUSG0000003453341
Q9R053 / Scn11a / Sodium channel protein type 11 subunit alpha / Q9UI33* / sodium voltage-gated channel alpha subunit 11*ENSMUSG0000003411538
Cacna1h / voltage-dependent T-type calcium channel subunit alpha-1H isoform 2 / O95180* / calcium voltage-gated channel subunit alpha1 H*ENSMUSG0000002411221
Cacna1i / calcium channel, voltage-dependent, alpha 1I subunit / Q9P0X4* / calcium voltage-gated channel subunit alpha1 I*ENSMUSG0000002241621
Cacna1g / calcium channel, voltage-dependent, T type, alpha 1G subunit / O43497* / calcium voltage-gated channel subunit alpha1 G*ENSMUSG0000002086621


Protein motifs (from Interpro)
Interpro ID Name
 IPR001696  Voltage gated sodium channel, alpha subunit
 IPR005821  Ion transport domain
 IPR010526  Sodium ion transport-associated
 IPR028812  Voltage gated sodium channel, alpha-7 subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006936 muscle contraction IEA
 biological_processGO:0019228 neuronal action potential IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0055078 sodium ion homeostasis IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0086010 membrane depolarization during action potential IBA
 cellular_componentGO:0001518 voltage-gated sodium channel complex IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0097386 glial cell projection IDA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IBA
 molecular_functionGO:0005272 sodium channel activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001986 taste sensitivity/ preferences 
Show

Allelic Composition: Gata1tm6Sho/Y
Genetic Background: involves: 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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