ENSMUSG00000023046


Mus musculus

Features
Gene ID: ENSMUSG00000023046
  
Biological name :Igfbp6
  
Synonyms : Igfbp6 / Insulin-like growth factor-binding protein 6 / P47880
  
Possible biological names infered from orthology : P24592
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: F2
Gene start: 102144362
Gene end: 102149511
  
Corresponding Affymetrix probe sets: 10427125 (MoGene1.0st)   1417933_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023807
NCBI entrez gene - 16012     See in Manteia.
MGI - MGI:96441
RefSeq - NM_008344
RefSeq Peptide - NP_032370
swissprot - P47880
Ensembl - ENSMUSG00000023046
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 igfbp6aENSDARG00000070941Danio rerio
 igfbp6bENSDARG00000090833Danio rerio
 IGFBP6ENSG00000167779Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Igfbp5 / Q07079 / Insulin-like growth factor-binding protein 5 / P24593*ENSMUSG0000002618536
Igfbp3 / P47878 / Insulin-like growth factor-binding protein 3 / P17936*ENSMUSG0000002042734
Igfbp2 / P47877 / Insulin-like growth factor-binding protein 2 / P18065*ENSMUSG0000003932331
Igfbp4 / P47879 / Insulin-like growth factor-binding protein 4 / P22692*ENSMUSG0000001749329
Igfbp1 / P47876 / Insulin-like growth factor-binding protein 1 / P08833*ENSMUSG0000002042925


Protein motifs (from Interpro)
Interpro ID Name
 IPR000716  Thyroglobulin type-1
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR009168  Insulin-like growth factor binding protein
 IPR017891  Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
 IPR022321  Insulin-like growth factor-binding protein family 1-6, chordata
 IPR022326  Insulin-like growth factor-binding protein 6
 IPR036857  Thyroglobulin type-1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0043567 regulation of insulin-like growth factor receptor signaling pathway IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0042568 insulin-like growth factor binary complex IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0031994 insulin-like growth factor I binding IEA
 molecular_functionGO:0031995 insulin-like growth factor II binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020053 Igf1 / P05017 / Insulin-like growth factor I / P05019* / insulin like growth factor 1*  / complex / reaction
 ENSMUSG00000048583 Igf2 / P09535 / Insulin-like growth factor II Insulin-like growth factor II Preptin / P01344* / insulin like growth factor 2*  / complex / reaction






 

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