| MP:0000439 | enlarged skull | |
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Allelic Composition: Zeb2tm1.2Yhi/Zeb2tm1.2Yhi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
|
| MP:0000583 | long toenails | "increased length of the toenails" [J:65045] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
|
| MP:0000755 | hindlimb paralysis | "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
|
| MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
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Allelic Composition: L1camtm1(tTA)Msch/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
|
| MP:0000822 | abnormal brain ventricle morphology | "malformed or absent fluid filled cavities of the cerebrum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: L1camtm1(tTA)Msch/Y
Genetic Background: involves: 129 * C57BL/6J
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| MP:0000825 | dilated lateral ventricles | "increase over the normal size of the horseshoe-shaped cavities of the cerebrum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:38857] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000828 | abnormal fourth ventricle morphology | "malformed or absent irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind; it is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000849 | abnormal cerebellum morphology | "any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
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Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
|
| MP:0000854 | abnormal cerebellum development | "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
|
| MP:0000857 | abnormal cerebellar foliation | "malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951] |
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Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
|
| MP:0000866 | vermis hypoplasia | "reduced cell number in the vermis" [J:61509] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0000872 | abnormal external granule cell layer | "malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
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| MP:0000886 | abnormal cerebellar granule layer | "any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
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| MP:0000968 | abnormal sensory neuron innervation | "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0001106 | abnormal Schwann cell | "malformed or absent cells which form the insulating myelin sheaths of peripheral axons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Zeb2tm1.2Yhi/Zeb2tm1.2Yhi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0001349 | excessive tearing | "an unusually high amount of fluid secreted by the lacrimal glands, often resulting in overflow of fluid from the eye" [hdene:Howard Dene, Mouse Genome Informatics Curator, J:38104] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0001360 | abnormal social investigation | "altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Smg6tm1.1Zqw/Smg6tm1.1Zqw,Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae
|
| MP:0001364 | decreased anxiety-related response | "when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043] |
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Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
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Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: L1camtm3.1Vlem/Y
Genetic Background: either: 129S4.129S2-L1camtm3.1Vlem or B6.129S4-L1camtm3.1Vlem
Allelic Composition: L1camtm4.1Vlem/Y
Genetic Background: either: 129S4.129S2-L1camtm4.1Vlem or B6.129S4-L1camtm4.1Vlem
|
| MP:0001415 | increased exploration in new environment | "greater amount of time spent investigating new location" [J:28825] |
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Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0001441 | increased grooming behavior | "increased amount of time spent cleaning and/or keeping outward appearance tidy (self, mate or offspring)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Smg6tm1.1Zqw/Smg6tm1.1Zqw,Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae
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| MP:0001463 | abnormal spatial learning | "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University] |
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Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
|
| MP:0001524 | impaired limb coordination | "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0001891 | hydroencephaly | "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy
Genetic Background: Not Specified
Allelic Composition: L1camtm1(tTA)Msch/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0002066 | abnormal motor capabilities/coordination/movement | "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hrm1Enu/Hrm1Enu
Genetic Background: BALB/cJ-Hrm1Enu
Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0002082 | postnatal lethality | "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcam+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
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| MP:0002152 | abnormal brain morphology | "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0002206 | abnormal CNS synaptic transmission | "defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0002557 | abnormal social/conspecific interaction | "deviation of the normal behavior of mice towards each other" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Il2rgtm1Wjl/Il2rgtm1Wjl,Prkdcscid/Prkdcscid
Genetic Background: NOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz
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| MP:0002574 | increased vertical activity | "greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator] |
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Allelic Composition: Sox3tm1.1Lja/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0002733 | abnormal thermal nociception | "abnormal capability to sense pain elicited by thermal stimulation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0002797 | thigmotaxis | "preference of a mouse for the side walls of a cage or box; usually an indicator of increased anxiety response" [J:56814] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0002878 | abnormal corticospinal tract | "anomaly in the structure or function of the fibers that arise from the cells within the cerebral cortex, pass through the medullary pyramid, and descend in the spinal cord" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0002882 | abnormal neuron | "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0002961 | abnormal axon guidance | "defect in the signaling mechanisms that allow precise navigation and connections of axonal growth cones to effector tissues " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
Allelic Composition: L1camtm1.1Pfm/L1camtm1.1Pfm
Genetic Background: Not Specified
Allelic Composition: L1camtm1.1Pfm/Y
Genetic Background: Not Specified
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| MP:0003651 | abnormal axon outgrowth | "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0004097 | abnormal cerebellar cortex morphology | "any structural anomaly of the thin mantle of gray matter that covers the surface of each cerebral hemisphere, including the six layers of nerve cells and the nerve pathways that connect them; together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcamtm1Gmt
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
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| MP:0005316 | abnormal response to tactile stimuli | "anomalous reflex action normally induced by touch or pain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0005423 | abnormal somatic nervous system physiology | "anomalous function of any of the cranial and spinal nerves or their ganglia or the peripheral sensory receptors" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0005537 | abnormal cerebral aqueduct | "anomalous structure of the channel in the mesencephalon that connets the third and fourth ventricles" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, hdene:Howard Dene , Mouse Genome Informatics Curator] |
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Allelic Composition: L1camtm1(tTA)Msch/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0006198 | enophthalmos | "sinking or retraction of the eye back into the socket" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0006254 | thin cerebral cortex | "decreased depth of the mantle covering the surface of the cerebral hemispheres" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:84683] |
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Allelic Composition: L1camtm1(tTA)Msch/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
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| MP:0006282 | abnormal posterior horn morphology | "any structural anomaly of the dorsal gray matter of the spinal cord" [J:77764, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0008056 | abnormal retinal ganglion cell morphology | "any structural anomaly of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: L1camtm1.1Pfm/L1camtm1.1Pfm
Genetic Background: Not Specified
Allelic Composition: L1camtm1.1Pfm/Y
Genetic Background: Not Specified
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| MP:0008415 | abnormal neurite morphology | "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572] |
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Allelic Composition: L1camtm3.1Vlem/Y
Genetic Background: either: 129S4.129S2-L1camtm3.1Vlem or B6.129S4-L1camtm3.1Vlem
Allelic Composition: L1camtm4.1Vlem/Y
Genetic Background: either: 129S4.129S2-L1camtm4.1Vlem or B6.129S4-L1camtm4.1Vlem
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| MP:0008489 | postnatal slow weight gain | "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0008534 | enlarged fourth ventricle | "increased size of the irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind; it is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space" [MESH:A08.186.211.276.500, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: L1camtm1Sor/Y
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Ttc26hop-hpy/Ttc26hop-hpy
Genetic Background: Not Specified
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Fzr1Gt(RRJ067)Byg/Fzr1Gt(RRJ067)Byg
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: L1camtm1Sor/Y,Nrcamtm1Gmt/Nrcam+
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * Swiss Webster
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| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Prdm2tm1Shg/Prdm2tm1Shg,Trp53tm1Tyj/Trp53+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: L1camtm1.1Vlem/L1camtm1.1Vlem
Genetic Background: B6.Cg-L1camtm1.1Vlem
Allelic Composition: L1camtm1Sor/Y
Genetic Background: either: 129S7/SvEvBrd-L1camtm1Sor or (129S7/SvEvBrd * C57BL/6J)F1
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| MP:0011275 | abnormal behavioral response to light | "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2] |
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Allelic Composition: Smg6tm1.1Zqw/Smg6tm1.1Zqw,Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae
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| MP:0011380 | enlarged brain ventricle | "increased size of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord" [MGI:smb] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0012484 | decreased corticospinal tract size | "reduced size of the corticospinal fibers that arise from the pyramidal cells within the cerebral cortex layer V of the precentral motor area, the premotor area and the postcentral gyrus, then descend into and through the medulla to form the lateral corticospinal tract and the anterior corticospinal tract" [ISBN:0-683-40008-8] |
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Allelic Composition: L1camtm1Mtei/Y
Genetic Background: either: (involves: 129/Sv * C57BL/6J) or (involves: 129/Sv * 129S/SvEv)
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| MP:0014185 | cerebellum atrophy | "acquired diminution of the size of the cerebellum associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:Anna] |
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Allelic Composition: L1camtm1(tTA)Msch/Y
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: L1camtm1Mtei/Y
Genetic Background: involves: 129 * C57BL/6J
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