ENSMUSG00000032480


Mus musculus

Features
Gene ID: ENSMUSG00000032480
  
Biological name :Dhx30
  
Synonyms : Dhx30 / Putative ATP-dependent RNA helicase DHX30 / Q99PU8
  
Possible biological names infered from orthology : DExH-box helicase 30 / Q7L2E3
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F2
Gene start: 110084320
Gene end: 110117830
  
Corresponding Affymetrix probe sets: 10597103 (MoGene1.0st)   1416140_a_at (Mouse Genome 430 2.0 Array)   1438832_x_at (Mouse Genome 430 2.0 Array)   1438969_x_at (Mouse Genome 430 2.0 Array)   1453251_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142659
Ensembl peptide - ENSMUSP00000143751
Ensembl peptide - ENSMUSP00000143700
Ensembl peptide - ENSMUSP00000143616
Ensembl peptide - ENSMUSP00000143607
Ensembl peptide - ENSMUSP00000143529
Ensembl peptide - ENSMUSP00000143371
Ensembl peptide - ENSMUSP00000143272
Ensembl peptide - ENSMUSP00000142952
Ensembl peptide - ENSMUSP00000142846
Ensembl peptide - ENSMUSP00000142836
Ensembl peptide - ENSMUSP00000062622
Ensembl peptide - ENSMUSP00000107622
Ensembl peptide - ENSMUSP00000129174
Ensembl peptide - ENSMUSP00000142489
Ensembl peptide - ENSMUSP00000142549
Ensembl peptide - ENSMUSP00000142636
NCBI entrez gene - 72831     See in Manteia.
MGI - MGI:1920081
RefSeq - XM_006512298
RefSeq - XM_006512299
RefSeq - XM_017313614
RefSeq - XM_017313613
RefSeq - XM_011243029
RefSeq - XM_006512310
RefSeq - XM_006512305
RefSeq - XM_006512304
RefSeq - XM_006512303
RefSeq - NM_001252682
RefSeq - NM_001252683
RefSeq - NM_133347
RefSeq - XM_017313616
RefSeq - XM_006512301
RefSeq - XM_006512300
RefSeq - XM_017313615
RefSeq Peptide - NP_001239612
RefSeq Peptide - NP_001239611
RefSeq Peptide - NP_579925
swissprot - Q99PU8
swissprot - A0A0G2JGY7
swissprot - A0A0G2JE53
swissprot - A0A0G2JEN0
swissprot - A0A0G2JEN9
swissprot - A0A0G2JEY7
swissprot - A0A0G2JFR1
swissprot - A0A0G2JGD9
swissprot - A0A0G2JGL1
swissprot - A0A0G2JGL8
swissprot - A0A0G2JGU3
Ensembl - ENSMUSG00000032480
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhx30ENSDARG00000077839Danio rerio
 DHX30ENSGALG00000039830Gallus gallus
 DHX30ENSG00000132153Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dhx57 / Q6P5D3 / Putative ATP-dependent RNA helicase DHX57 / Q6P158* / DExH-box helicase 57*ENSMUSG0000003505127
Dhx29 / Q6PGC1 / ATP-dependent RNA helicase DHX29 / Q7Z478* / DExH-box helicase 29*ENSMUSG0000004242625
Dhx36 / Q8VHK9 / ATP-dependent RNA helicase DHX36 / Q9H2U1* / DEAH-box helicase 36*ENSMUSG0000002777024
B2RR83 / Ythdc2 / YTH domain containing 2 / Q9H6S0*ENSMUSG0000003465324
Dhx9 / DExH-box helicase 9 / Q08211*ENSMUSG0000004269923
Tdrd9 / Q14BI7 / ATP-dependent RNA helicase TDRD9 / Q8NDG6* / tudor domain containing 9*ENSMUSG0000005400317


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing IBA
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:1902775 mitochondrial large ribosomal subunit assembly ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0035770 ribonucleoprotein granule ISS
 cellular_componentGO:0042645 mitochondrial nucleoid ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003682 chromatin binding ISS
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003725 double-stranded RNA binding ISO
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0004180 failure of initiation of embryo turning "failure to begin the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0006386 absent somites "missing all somites" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Dicer1tm1.1Doca/Dicer1tm1.1Doca
Genetic Background: involves: 129P2/OlaHsd * BALB/cJ * C57BL/6

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi

 MP:0013279 increased fasted circulating glucose level "increase in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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