ENSMUSG00000042426


Mus musculus

Features
Gene ID: ENSMUSG00000042426
  
Biological name :Dhx29
  
Synonyms : ATP-dependent RNA helicase DHX29 / Dhx29 / Q6PGC1
  
Possible biological names infered from orthology : DExH-box helicase 29 / Q7Z478
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: D2.2
Gene start: 112927454
Gene end: 112969432
  
Corresponding Affymetrix probe sets: 10407222 (MoGene1.0st)   1434710_at (Mouse Genome 430 2.0 Array)   1439076_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035244
Ensembl peptide - ENSMUSP00000153182
NCBI entrez gene - 218629     See in Manteia.
MGI - MGI:2145374
RefSeq - NM_172594
RefSeq Peptide - NP_766182
swissprot - Q6PGC1
swissprot - Q8BN72
Ensembl - ENSMUSG00000042426
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dhx29ENSDARG00000040326Danio rerio
 DHX29ENSGALG00000014700Gallus gallus
 DHX29ENSG00000067248Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dhx57 / Q6P5D3 / Putative ATP-dependent RNA helicase DHX57 / Q6P158* / DExH-box helicase 57*ENSMUSG0000003505130
Dhx36 / Q8VHK9 / ATP-dependent RNA helicase DHX36 / Q9H2U1* / DEAH-box helicase 36*ENSMUSG0000002777026
Dhx9 / DExH-box helicase 9 / Q08211*ENSMUSG0000004269924
B2RR83 / Ythdc2 / YTH domain containing 2 / Q9H6S0*ENSMUSG0000003465324
Dhx30 / Q99PU8 / Putative ATP-dependent RNA helicase DHX30 / Q7L2E3* / DExH-box helicase 30*ENSMUSG0000003248022
Tdrd9 / Q14BI7 / ATP-dependent RNA helicase TDRD9 / Q8NDG6* / tudor domain containing 9*ENSMUSG0000005400318


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR034730  ATP-dependent RNA helicase DHX29


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006396 RNA processing IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043024 ribosomal small subunit binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
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Allelic Composition: Cks2TgTn(sb-cHS4,Tyr)2525F-2Ove/Cks2TgTn(sb-cHS4,Tyr)2525F-2Ove
Genetic Background: FVB/N-Cks2TgTn(sb-cHS4,Tyr)2525F-2Ove

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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