ENSMUSG00000033080


Mus musculus

Features
Gene ID: ENSMUSG00000033080
  
Biological name :Vsx1
  
Synonyms : Q91V10 / visual system homeobox 1 / Vsx1
  
Possible biological names infered from orthology : Q9NZR4
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: G3
Gene start: 150680702
Gene end: 150689360
  
Corresponding Affymetrix probe sets: 10488497 (MoGene1.0st)   1422104_at (Mouse Genome 430 2.0 Array)   1450487_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039088
NCBI entrez gene - 114889     See in Manteia.
MGI - MGI:1890816
RefSeq - NM_054068
RefSeq Peptide - NP_473409
swissprot - A2AQX5
swissprot - Q91V10
Ensembl - ENSMUSG00000033080
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vsx1ENSDARG00000056292Danio rerio
 VSX1ENSGALG00000037576Gallus gallus
 VSX1ENSG00000100987Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vsx2 / Q61412 / visual system homeobox 2 / P58304*ENSMUSG0000002123941
Arx / O35085 / Homeobox protein ARX / Q96QS3* / aristaless related homeobox*ENSMUSG0000003527722
Uncx / O08934 / UNC homeobox / A6NJT0*ENSMUSG0000002954622
Alx4 / O35137 / Homeobox protein aristaless-like 4 / Q9H161* / ALX homeobox 4*ENSMUSG0000004031021
Rax / O35602 / Retinal homeobox protein Rx / Q9Y2V3* / retina and anterior neural fold homeobox*ENSMUSG0000002451820
Alx1 / Q8C8B0 / ALX homeobox protein 1 / Q15699* / ALX homeobox 1*ENSMUSG0000003660219
Alx3 / O70137 / Homeobox protein aristaless-like 3 / O95076* / ALX homeobox 3*ENSMUSG0000001460318
O35690 / Phox2b / Paired mesoderm homeobox protein 2B / Q99453* / paired like homeobox 2b*ENSMUSG0000001252017
Phox2a / Q62066 / Paired mesoderm homeobox protein 2A / O14813* / paired like homeobox 2a*ENSMUSG0000000794617
Isx / A1A546 / intestine specific homeobox / Q2M1V0*ENSMUSG0000003162117
Prrxl1 / Q8BYH0 / paired related homeobox protein-like 1 / DRGX* / A6NNA5* / dorsal root ganglia homeobox*ENSMUSG0000004173016


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR023339  CVC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007601 visual perception IMP
 biological_processGO:0042551 neuron maturation IGI
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0060040 retinal bipolar neuron differentiation IMP
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gusbmps/Gusbmps,KitW-41J/KitW-41J
Genetic Background: B6(C)-KitW-41J Gusbmps/BrkJ

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Tlr9tm1Aki/Tlr9tm1Aki
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

Allelic Composition: Vsx1tm2Mci/Vsx1tm2Mci
Genetic Background: either: (involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss)

 MP:0006073 abnormal retinal bipolar cell morphology "anomalous structure of the cells that transmit signals from the photoreceptors to retinal amacrine and ganglion cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92623:]
Show

Allelic Composition: Irx6tm1Chow/Irx6tm1Chow,Vsx1tm1Mci/Vsx1tm1Mci
Genetic Background: involves: 129S1/Sv * 129S1/SvImj * 129X1/SvJ

 MP:0006075 abnormal retinal cone bipolar cell morphology "anomalous structure of the retinal bipolar cells that connect to both ganglion and amacrine cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92623]
Show

Allelic Composition: Tlr9tm1Aki/Tlr9tm1Aki
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

Allelic Composition: Vsx1tm2Mci/Vsx1tm2Mci
Genetic Background: either: (involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * Black Swiss)

Allelic Composition: Vsx1tm1Bhr/Vsx1tm2Bhr
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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