ENSMUSG00000033191


Mus musculus

Features
Gene ID: ENSMUSG00000033191
  
Biological name :Tie1
  
Synonyms : Q06806 / Tie1 / tyrosine kinase with immunoglobulin-like and EGF-like domains 1
  
Possible biological names infered from orthology : P35590
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.1
Gene start: 118471191
Gene end: 118490061
  
Corresponding Affymetrix probe sets: 10515771 (MoGene1.0st)   1416238_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037129
Ensembl peptide - ENSMUSP00000139279
NCBI entrez gene - 21846     See in Manteia.
MGI - MGI:99906
RefSeq - NM_011587
RefSeq Peptide - NP_035717
swissprot - Q06806
swissprot - Q6PAP2
Ensembl - ENSMUSG00000033191
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tie1ENSDARG00000004105Danio rerio
 TIE1ENSGALG00000009957Gallus gallus
 TIE1ENSG00000066056Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tek / Q02858 / TEK receptor tyrosine kinase / Q02763*ENSMUSG0000000638646
Axl / Q00993 / AXL receptor tyrosine kinase / P30530*ENSMUSG0000000260218
Mst1r / Q62190 / macrophage stimulating 1 receptor (c-met-related tyrosine kinase) / Q04912* / macrophage stimulating 1 receptor*ENSMUSG0000003258418
Mertk / Q60805 / Tyrosine-protein kinase Mer / Q12866* / MER proto-oncogene, tyrosine kinase*ENSMUSG0000001436117
Tyro3 / P55144 / TYRO3 protein tyrosine kinase 3 / Q06418* / TYRO3 protein tyrosine kinase*ENSMUSG0000002729817
Met / MET proto-oncogene, receptor tyrosine kinase / P08581*ENSMUSG0000000937616
Ryk / Q01887 / Tyrosine-protein kinase RYK / receptor-like tyrosine kinase*ENSMUSG0000003254712


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000742  EGF-like domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013032  EGF-like, conserved site
 IPR013151  Immunoglobulin
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001701 in utero embryonic development IGI
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0032526 response to retinoic acid IDA
 biological_processGO:0045026 plasma membrane fusion IMP
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISM
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000259 abnormal vascular development "malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509]
Show

Allelic Composition: Icostm1Flv/Icostm1Flv,Tg(Cd4-Maf)6666Glm/0
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0000263 absent organized vascular network "formation of vasculature, but failure to differentiate into stereotypic organized pattern" [J:53370]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0000267 abnormal cardiac development "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0000291 enlarged pericardium "extended fibroserous membrane covering the heart and beginning of the great vessels" [J:29971]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0000496 abnormal small intestine morphology "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0001179 thicker alveolar septa 
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001688 abnormal somite development "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001785 edema "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]
Show

Allelic Composition: Mpgtm1Rhe/Mpgtm1Rhe
Genetic Background: B6.129P2-Mpgtm1Rhe

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tie1tm1Scba/Tie1tm1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Tie1tm1Geno/Tie1tm1Geno
Genetic Background: involves: ICR

Allelic Composition: Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR

Allelic Composition: Tie1tm2Vlcg/Tie1tm2Vlcg
Genetic Background: Not Specified

 MP:0001786 skin edema "accumulation of an excessive amount of fluid in the skin" [J:65039]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0001879 abnormal lymphatic vessel morphology "malformation of the network of vessels which carries lymph around the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Glatm1Kul/Y,Itpr1wblo/Itpr1wblo
Genetic Background: B6;129-Glatm1Kul Itpr1wblo/GrsrJ

Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

Allelic Composition: Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tie1tm1Scba/Tie1tm1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Glatm1Kul/Y,Itpr1wblo/Itpr1wblo
Genetic Background: B6;129-Glatm1Kul Itpr1wblo/GrsrJ

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tgfbr1tm1.1Vlcg/Tgfbr1tm1.1Vlcg
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

 MP:0002188 small heart "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0002189 abnormal myocardial trabeculae morphology "malformation of the supporting bundles of muscular fibers lining the walls of the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0002925 abnormal cardiovascular development "aberrant formation or incomplete differentiation of the cardiovascular system" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003105 abnormal heart atrium morphology "structural anomaly of one or both of the two upper chambers of the heart " [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0003227 abnormal vascular branching morphogenesis "increase, decrease or anomaly in the process by which new vessels sprout off pre-existing vessels" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0003229 abnormal vitelline vasculature "malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003232 abnormal forebrain development "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0003288 intestinal edema "an accumulation of an excessive amount of serous fluid in the intestine or intestinal cells " [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0003542 abnormal vascular endothelial cell development "malformation or aberrant differentiation of the cells that line the vasculature" [J:95387, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0003659 abnormal lymph circulation "abnormalities in the flow of the lymph from the tissues into the veins of the circulatory system" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:95885]
Show

Allelic Composition: Tie1tm1Scba/Tie1tm1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003828 pulmonary edema "an accumulation of an excessive amount of watery fluid in the lung " [J:44108, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0003974 abnormal endocardium morphology "malformation of the thin serous membrane, primarily composed of endothelial tissue, that lines the interior of the heart" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

Allelic Composition: Tie1tm1Sato/Tie1tm1Sato
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0004076 abnormal vitelline vascular remodelling "anomaly in the conversion of the primary (honeycomb-like) vascular plexus of the yolk sac into a mature vascular network" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0004106 lymphatic vessel hyperplasia "increased cell number in lymphatic vessels" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tie1tm1Scba/Tie1tm1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0004938 dilated vasculature "stretched or widened aperture of the luminal space of the network of tubes that carries blood through the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0005325 abnormal glomerulus "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0005602 decreased angiogenesis "reduced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0006055 abnormal vascular endothelial cell morphology "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0006138 congestive heart failure "the heart is unable to adequately pump blood throughout the body" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0008778 lymphangiogenesis "any anomaly in the formation of lymphatic vessels from pre-existing lymphatic vessels" [MESH:G07.574.500.325.377.500]
Show

Allelic Composition: Tie1tm1Scba/Tie1tm1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

Allelic Composition: Tie1tm1Geno/Tie1tm1Geno
Genetic Background: involves: ICR

Allelic Composition: Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR

 MP:0009698 heart hemorrhage "bleeding into the heart" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Tie1tm1Scba/Tie1tm1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tie1tm1.1Scba/Tie1tm1.1Scba
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Tektm1Sato/Tektm1Sato
Genetic Background: either: (involves: 129S1/Sv * 129T2/SvEmsJ) or (involves: 129S1/Sv * C57BL/6J)

 MP:0013241 embryo tissue necrosis "morphological changes resulting from pathological death of some or all embryo tissue; usually due to irreversible damage" [MGI:csmith]
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Allelic Composition: Tektm1Dmt/Tektm1Dmt,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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