ENSMUSG00000034336


Mus musculus

Features
Gene ID: ENSMUSG00000034336
  
Biological name :Ina
  
Synonyms : Ina / internexin neuronal intermediate filament protein, alpha / P46660
  
Possible biological names infered from orthology : Q16352
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 47014698
Gene end: 47025327
  
Corresponding Affymetrix probe sets: 10463732 (MoGene1.0st)   10463737 (MoGene1.0st)   1418178_at (Mouse Genome 430 2.0 Array)   1448991_a_at (Mouse Genome 430 2.0 Array)   1448992_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041347
NCBI entrez gene - 226180     See in Manteia.
MGI - MGI:96568
RefSeq - NM_146100
RefSeq Peptide - NP_666212
swissprot - P46660
Ensembl - ENSMUSG00000034336
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 inaaENSDARG00000011862Danio rerio
 inabENSDARG00000053248Danio rerio
 INAENSG00000148798Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nefm / neurofilament medium / P07197*ENSMUSG0000002205446
Nefl / P08551 / Neurofilament light polypeptide / P07196* / neurofilament light*ENSMUSG0000002205546
Vim / P20152 / vimentin / P08670*ENSMUSG0000002672843
Des / P31001 / Desmin / P17661*ENSMUSG0000002620842
Prph / peripherin / P41219*ENSMUSG0000002348442
Nefh / P19246 / Neurofilament heavy polypeptide / P12036* / neurofilament heavy*ENSMUSG0000002039641
Gfap / P03995 / Glial fibrillary acidic protein / P14136*ENSMUSG0000002093239
Lmnb1 / P14733 / Lamin-B1 / P20700*ENSMUSG0000002459024
Lmna / P48678 / Prelamin-A/C Lamin-A/C / P02545* / lamin A/C*ENSMUSG0000002806324
Lmnb2 / P21619 / Lamin-B2 / Q03252*ENSMUSG0000006207524


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR006821  Intermediate filament head, DNA-binding domain
 IPR018039  Intermediate filament protein, conserved site
 IPR027703  Alpha-internexin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045104 intermediate filament cytoskeleton organization IMP
 biological_processGO:0060052 neurofilament cytoskeleton organization IGI
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0005883 neurofilament IDA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0004768 abnormal axonal transport "any functional anomaly of the directed movement of organelles or vesicles along microtubules in nerve cell axons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Inatm1Jpj/Inatm1Jpj,Nefmtm1Jpj/Nefmtm1Jpj
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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