ENSMUSG00000035177


Mus musculus

Features
Gene ID: ENSMUSG00000035177
  
Biological name :Nlrp2
  
Synonyms : Nlrp2
  
Possible biological names infered from orthology : NLR family pyrin domain containing 2 / NLR family pyrin domain containing 7 / NLRP7 / Q8WX94 / Q9NX02
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A1
Gene start: 5298547
Gene end: 5351035
  
Corresponding Affymetrix probe sets: 10559730 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000045077
Ensembl peptide - ENSMUSP00000147102
Ensembl peptide - ENSMUSP00000146451
NCBI entrez gene - 232827     See in Manteia.
MGI - MGI:3041206
RefSeq - NM_177690
RefSeq Peptide - NP_808358
swissprot - A0A140LJ71
swissprot - A0A140LHK4
swissprot - Q4PLS0
Ensembl - ENSMUSG00000035177
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO704635.1ENSDARG00000105141Danio rerio
 nlrb5ENSDARG00000090699Danio rerio
 si:ch211-66k16.2ENSDARG00000095634Danio rerio
 si:ch211-66k16.28ENSDARG00000088423Danio rerio
 NLRP2ENSG00000022556Homo sapiens
 NLRP7ENSG00000167634Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nlrp3 / Q8R4B8 / NACHT, LRR and PYD domains-containing protein 3 / Q96P20* / NLR family pyrin domain containing 3*ENSMUSG0000003269127
E9Q5R7 / Nlrp12 / NACHT, LRR and PYD domains-containing protein 12 / P59046* / NLR family pyrin domain containing 12*ENSMUSG0000007881726
Nlrp14 / Q6B966 / NACHT, LRR and PYD domains-containing protein 14 / Q86W24* / NLR family pyrin domain containing 14*ENSMUSG0000001662625
Nlrp4c / Q3TKR3 / NACHT, LRR and PYD domains-containing protein 4C / NLRP4* / Q96MN2* / NLR family pyrin domain containing 4*ENSMUSG0000003469025
Nlrp4a / Q8BU40 / NACHT, LRR and PYD domains-containing protein 4A / NLRP4* / Q96MN2* / NLR family pyrin domain containing 4*ENSMUSG0000004060125
Nlrp4e / Q66X19 / NACHT, LRR and PYD domains-containing protein 4E / NLRP4* / Q96MN2* / NLR family pyrin domain containing 4*ENSMUSG0000004569324
Nlrp9b / Q66X22 / NACHT, LRR and PYD domains-containing protein 9B / NLRP9* / Q7RTR0* / NLR family pyrin domain containing 9*ENSMUSG0000006050824
Nlrp4f / NLRP4* / Q96MN2* / NLR family pyrin domain containing 4*ENSMUSG0000003299924
Nlrp9c / Q66X01 / NACHT, LRR and PYD domains-containing protein 9C / NLRP9* / Q7RTR0* / NLR family pyrin domain containing 9*ENSMUSG0000004061423
Nlrp5 / Q9R1M5 / NACHT, LRR and PYD domains-containing protein 5 / P59047* / NLR family pyrin domain containing 5*ENSMUSG0000001572123
Nlrp9a / NACHT, LRR and PYD domains-containing protein 9A isoform 3 / NLRP9* / Q7RTR0* / NLR family pyrin domain containing 9*ENSMUSG0000005410223
Nlrp6 / Q91WS2 / NACHT, LRR and PYD domains-containing protein 6 / P59044* / NLR family pyrin domain containing 6*ENSMUSG0000003874521
Nlrp4b / Q8C6J9 / Mus musculus NLR family, pyrin domain containing 4B (Nlrp4b), transcript variant 2, mRNA. / NLRP4* / Q96MN2* / NLR family pyrin domain containing 4*ENSMUSG0000003408720
Nlrp1a / Q2LKU9 / NACHT, LRR and PYD domains-containing protein 1a / NLRP1* / Q9C000* / NLR family pyrin domain containing 1*ENSMUSG0000006983019
A1Z198 / Nlrp1b / NACHT, LRR and PYD domains-containing protein 1b allele 2 / NLRP1* / Q9C000* / NLR family pyrin domain containing 1*ENSMUSG0000007039018
Nlrp10 / Q8CCN1 / NACHT, LRR and PYD domains-containing protein 10 / Q86W26* / NLR family pyrin domain containing 10*ENSMUSG0000004970912
Rnh1 / Q91VI7 / Ribonuclease inhibitor / P13489* / ribonuclease/angiogenin inhibitor 1*ENSMUSG0000003865011


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR004020  DAPIN domain
 IPR007111  NACHT nucleoside triphosphatase
 IPR011029  Death-like domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion ISO
 cellular_componentGO:0000784 nuclear chromosome, telomeric region ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0032090 Pyrin domain binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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