Manteia

ENSMUSG00000051391

Mus musculus

Features

Gene ID:	ENSMUSG00000051391

Biological name :	Ywhag

Synonyms :	P61982 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide / Ywhag

Possible biological names infered from orthology :	P61981 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

Species:	Mus musculus

Chr. number:	5
Strand:	-1
Band:	G2
Gene start:	135908409
Gene end:	135934616

Corresponding Affymetrix probe sets:	10534531 (MoGene1.0st) 1420816_at (Mouse Genome 430 2.0 Array) 1420817_at (Mouse Genome 430 2.0 Array) 1450012_x_at (Mouse Genome 430 2.0 Array) 1459693_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000143631 Ensembl peptide - ENSMUSP00000051223 NCBI entrez gene - 22628 See in Manteia. MGI - MGI:108109 RefSeq - NM_018871 RefSeq Peptide - NP_061359 swissprot - A8IP69 swissprot - P61982 Ensembl - ENSMUSG00000051391

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Ywhah / P68510 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide / Q04917* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta*	ENSMUSG00000018965	87
Ywhab / Q9CQV8 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide / P31946* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta*	ENSMUSG00000018326	75
Ywhaz / P63101 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	ENSMUSG00000022285	74
Ywhaq / P68254 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta	ENSMUSG00000076432	69
Sfn / O70456 / stratifin / P31947*	ENSMUSG00000047281	64
Ywhae / P62259 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide / P62258* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation prote...	ENSMUSG00000020849	62

Protein motifs (from Interpro)

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006605	protein targeting	IDA
biological_process	GO:0032869	cellular response to insulin stimulus	IEA
biological_process	GO:0045664	regulation of neuron differentiation	ISS
biological_process	GO:0048167	regulation of synaptic plasticity	ISO
biological_process	GO:0055114	oxidation-reduction process	IEA
cellular_component	GO:0005622	intracellular	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005829	cytosol	TAS
cellular_component	GO:0030659	cytoplasmic vesicle membrane	TAS
cellular_component	GO:0031982	vesicle	IEA
cellular_component	GO:0043209	myelin sheath	IDA
molecular_function	GO:0003779	actin binding	ISS
molecular_function	GO:0004497	monooxygenase activity	IEA
molecular_function	GO:0005080	protein kinase C binding	ISS
molecular_function	GO:0005159	insulin-like growth factor receptor binding	ISS
molecular_function	GO:0005515	protein binding	IPI
molecular_function	GO:0019904	protein domain specific binding	IDA
molecular_function	GO:0030971	receptor tyrosine kinase binding	IEA
molecular_function	GO:0042802	identical protein binding	IEA

Pathways (from Reactome)

Pathway description

Activation of BAD and translocation to mitochondria

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Cckar^tm1Kym/Cckar^tm1Kym,Cckbr^tm1Tom/Cckbr^tm1Tom Genetic Background: involves: 129S4/SvJae * C57BL/6J

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000051391	Ywhag / P61982 / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide / P61981* / tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma*	/ complex

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr