ENSMUSG00000054988


Mus musculus

Features
Gene ID: ENSMUSG00000054988
  
Biological name :Agtr1b
  
Synonyms : Agtr1b / P29755 / Type-1B angiotensin II receptor
  
Possible biological names infered from orthology : AGTR1 / angiotensin II receptor type 1 / P30556
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: A2
Gene start: 20314473
Gene end: 20367177
  
Corresponding Affymetrix probe sets: 10497475 (MoGene1.0st)   1446527_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068298
Ensembl peptide - ENSMUSP00000128724
NCBI entrez gene - 11608     See in Manteia.
MGI - MGI:87965
RefSeq - NM_175086
RefSeq Peptide - NP_780295
swissprot - P29755
Ensembl - ENSMUSG00000054988
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 agtr1aENSDARG00000018616Danio rerio
 agtr1bENSDARG00000045443Danio rerio
 AGTR1ENSGALG00000038512Gallus gallus
 AGTR1ENSG00000144891Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Agtr1a / P29754 / Type-1A angiotensin II receptor / AGTR1* / P30556* / angiotensin II receptor type 1*ENSMUSG0000004911594
Agtr2 / P35374 / Type-2 angiotensin II receptor / P50052* / angiotensin II receptor type 2*ENSMUSG0000006812231
Aplnr / Q9WV08 / Apelin receptor / P35414*ENSMUSG0000004433829
Rxfp3 / Q8BGE9 / Relaxin-3 receptor 1 / Q9NSD7* / relaxin/insulin like family peptide receptor 3*ENSMUSG0000006073529
Bdkrb1 / Q61125 / B1 bradykinin receptor / P46663* / bradykinin receptor B1*ENSMUSG0000004134727
Ackr3 / P56485 / atypical chemokine receptor 3 / P25106*ENSMUSG0000004433726
Bdkrb2 / P32299 / B2 bradykinin receptor / P30411* / bradykinin receptor B2*ENSMUSG0000002107026
Gpr15 / Q0VDU3 / G-protein coupled receptor 15 / P49685*ENSMUSG0000004729326
Gpr25 / P0C5I1 / Probable G-protein coupled receptor 25 / O00155* / G protein-coupled receptor 25*ENSMUSG0000005275926
Rxfp4 / Q7TQP4 / Relaxin-3 receptor 2 / Q8TDU9* / relaxin/insulin like family peptide receptor 4*ENSMUSG0000004974123
Gpr182 / G protein-coupled receptor 182 / O15218*ENSMUSG0000005839623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000190  Angiotensin II receptor type 1
 IPR000248  Angiotensin II receptor family
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IGI
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001822 kidney development IGI
 biological_processGO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin IGI
 biological_processGO:0006954 inflammatory response IGI
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0009651 response to salt stress IEA
 biological_processGO:0019229 regulation of vasoconstriction IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0035902 response to immobilization stress IEA
 biological_processGO:0038166 angiotensin-activated signaling pathway IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0042756 drinking behavior IMP
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045777 positive regulation of blood pressure IEA
 biological_processGO:0071549 cellular response to dexamethasone stimulus IEA
 biological_processGO:0086097 phospholipase C-activating angiotensin-activated signaling pathway IEA
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IEA
 biological_processGO:1990776 response to angiotensin IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0031983 vesicle lumen IEA
 molecular_functionGO:0001596 angiotensin type I receptor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004945 angiotensin type II receptor activity IEA
 molecular_functionGO:0017046 peptide hormone binding IEA
 molecular_functionGO:0043621 protein self-association IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000230 abnormal blood pressure "altered tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Myogtm1Whk/Myogtm2Whk
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000527 abnormal kidney development "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000530 abnormal kidney vasculature "malformation or malfunctioning of the blood vessel network of the organ of excretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001629 abnormal heart rate "greater than or fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001859 kidney inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002705 dilated renal tubules "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002834 decreased heart weight "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002843 decreased blood pressure "decreased tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003638 abnormal response/metabolism to endogenous compounds "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003675 kidney cysts "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Hprttm1(Ggt1-Agtr1)Cof/Y
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003918 decreased kidney weight "reduced heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004193 abnormal kidney papilla morphology "any structural anomaly of the apex of the renal pyramid that projects into a calyx" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004875 increased mean arterial blood pressure "increase in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004876 decreased mean arterial blood pressure "decrease in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005325 abnormal glomerulus "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
Show

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005416 abnormal circulating protein level "anomalous blood concentration of any of the macromolecules consisting of long chains of amino acids in peptide linkage" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005583 decreased renin activity "less than the normal ability of this enzyme to cleave angiotensinogen and create angiotensin I" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Hprttm1(Ggt1-Agtr1)Cof/Y
Genetic Background: involves: 129P2/OlaHsd

 MP:0008872 abnormal response to xenobiotics "any anomaly in the physiological or morphological changes induced by a foreign compound, such as changes in blood pressure, changes in hormone or protein levels or hypertrophy or hypotrophy of an organ" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010418 perimembraneous ventricular septal defect "abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010420 muscular ventricular septal defect "abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Agtr2tm1Tin
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof,Agtr2tm1Tin/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011305 dilated kidney calyx "an expansion in the lumen volume or area of any of the branches of the renal pelvis that surround each renal papilla and collect urine" [MGI:anna]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011306 absent kidney pelvis "absence of the funnel shaped proximal portion of the ureter, normally formed by convergence of the major calices" [MGI:anna]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011363 renal glomerulus atrophy "acquired diminution of the size of the capillary loops of the kidney associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011501 increased glomerular capsule space "increased volume of the luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries" [MGI:csmith]
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Allelic Composition: Agtr1atm1Unc/Agtr1atm1Unc,Agtr1btm1Cof/Agtr1btm1Cof
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011565 kidney papillary hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, of the apex of the renal pyramid that normally projects into a calyx" [MGI:anna]
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Allelic Composition: Agtr1atm1Tma/Agtr1atm1Tma,Agtr1btm1Ii/Agtr1btm1Ii
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031980 Agt / angiotensinogen / P01019*  / complex / reaction






 

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