ENSMUSG00000056854


Mus musculus

Features
Gene ID: ENSMUSG00000056854
  
Biological name :Pou3f4
  
Synonyms : P62515 / Pou3f4 / POU domain, class 3, transcription factor 4
  
Possible biological names infered from orthology : P49335 / POU class 3 homeobox 4
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: E1
Gene start: 110814280
Gene end: 110817207
  
Corresponding Affymetrix probe sets: 10601459 (MoGene1.0st)   1422164_at (Mouse Genome 430 2.0 Array)   1422165_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000077354
NCBI entrez gene - 18994     See in Manteia.
MGI - MGI:101894
RefSeq - NM_008901
RefSeq Peptide - NP_032927
swissprot - A6H6L6
swissprot - P62515
Ensembl - ENSMUSG00000056854
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POU3F4ENSGALG00000029329Gallus gallus
 P49335ENSG00000196767Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P31361 / Pou3f3 / POU domain, class 3, transcription factor 3 / P20264* / POU class 3 homeobox 3*ENSMUSG0000004551568
P31360 / Pou3f2 / POU domain, class 3, transcription factor 2 / P20265* / POU class 3 homeobox 2*ENSMUSG0000009513962
P21952 / Pou3f1 / POU domain, class 3, transcription factor 1 / Q03052* / POU class 3 homeobox 1*ENSMUSG0000009012553
Pou2f2 / Q00196 / POU domain, class 2, transcription factor 2 / P09086* / POU class 2 homeobox 2*ENSMUSG0000000849637
P25425 / Pou2f1 / POU domain, class 2, transcription factor 1 / P14859* / POU class 2 homeobox 1*ENSMUSG0000002656536
Pou2f3 / POU domain, class 2, transcription factor 3 / Q9UKI9* / POU class 2 homeobox 3*ENSMUSG0000003201535
P20263 / Pou5f1 / POU domain, class 5, transcription factor 1 / Q06416* / Q01860* / POU5F1B* / POU class 5 homeobox 1* / POU class 5 homeobox 1B*ENSMUSG0000002440634
Pou1f1 / Q00286 / POU domain, class 1, transcription factor 1 / P28069* / POU class 1 homeobox 1*ENSMUSG0000000484230
Pou4f3 / Q63955 / POU domain, class 4, transcription factor 3 / Q15319* / POU class 4 homeobox 3*ENSMUSG0000002449729
Pou4f2 / Q63934 / POU domain, class 4, transcription factor 2 / Q12837* / POU class 4 homeobox 2*ENSMUSG0000003168829
P17208 / Pou4f1 / POU domain, class 4, transcription factor 1 / Q01851* / POU class 4 homeobox 1*ENSMUSG0000004834928
Pou5f2 / POU domain class 5, transcription factor 2 / Q8N7G0*ENSMUSG0000009366824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000327  POU-specific domain
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR010982  Lambda repressor-like, DNA-binding domain superfamily
 IPR013847  POU domain
 IPR016362  POU-domain transcription factor, class 3
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0021879 forebrain neuron differentiation IMP
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0090103 cochlea morphogenesis IGI
 biological_processGO:2001054 negative regulation of mesenchymal cell apoptotic process IGI
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003680 AT DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000031 abnormal cochlea morphology "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Pou3f4tm1Tno/Y
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0000037 abnormal lateral semicircular canal "anomaly of the lateral long bony tube of the labyrinth that is involved in the sense of balance " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000048 abnormal stria vascularis "anomalous structure of the layer of highly vascularized pigmented granular cells on the outer wall of the cochlear duct" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0001282 short vibrissae "decreased length of the vibrissae" [J:30249]
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Allelic Composition: Card11unm/Card11unm
Genetic Background: C57BL/6JSfdAnu-Card11unm/Anu

 MP:0001394 circling "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295]
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Allelic Composition: Cebpbtm1Kish/Cebpbtm1Kish,Cebpdtm1Aki/Cebpdtm1Aki
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Pou3f4del-J/Pou3f4del-J
Genetic Background: C3HeB/FeJ-Pou3f4del-J/J

Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Card11unm/Card11unm
Genetic Background: C57BL/6JSfdAnu-Card11unm/Anu

 MP:0001410 head bobbing "compulsive up and down movement of the head" [J:17123]
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Allelic Composition: Cebpbtm1Kish/Cebpbtm1Kish,Cebpdtm1Aki/Cebpdtm1Aki
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Pou3f4del-J/Pou3f4del-J
Genetic Background: C3HeB/FeJ-Pou3f4del-J/J

Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001485 abnormal pinna reflex "failure to respond to an auditory stimulus by a characteristic ear twitch " [J:64900]
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Allelic Composition: Card11unm/Card11unm
Genetic Background: C57BL/6JSfdAnu-Card11unm/Anu

Allelic Composition: Pou3f4Slf/Pou3f4Slf
Genetic Background: C3H101H-Pou3f4Slf

 MP:0001522 impaired swimming "reduced ability or inability to swim" [J:45446, J:39081]
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Allelic Composition: Mc4rMhdahwe13/Mc4r+
Genetic Background: C3HeB/FeJ-Mc4rMhdahwe13

 MP:0001967 deafness "inability to hear" [J:57651]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Pou3f4tm1Tno/Y
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4+
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0002730 head shaking "compulsive movement of the head in the horizontal plane" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:274]
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Allelic Composition: Bloc1s6pa/Bloc1s6pa
Genetic Background: B6.Cg-Bloc1s6pa/J

Allelic Composition: Pou3f4Slf/Pou3f4Slf
Genetic Background: C3H101H-Pou3f4Slf

 MP:0003069 abnormal superior semicircular canal "anomaly of the upper, superior segment of the long bony tube of the labyrinth that is involved in the sense of balance" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Pou3f4Slf/Y
Genetic Background: C3H101H-Pou3f4Slf

Allelic Composition: Pou3f4Slf/Pou3f4Slf
Genetic Background: C3H101H-Pou3f4Slf

 MP:0003148 reduced cochlear coiling "a reduction in cochlear coiling or number of turns; in wild-type mice, the cochlea most commonly exhibits one and three-fourth turns" [J:56294, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0003167 abnormal scala tympani morphology "any malformation or absence of the division of the spiral canal of the cochlea lying on the basal side of the spiral lamina" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:56294]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004286 abnormal internal auditory canal "any structural abnormality in the canal beginning at the opening of the internal acoustic meatus in the posterior cranial fossa, passing laterally through the petrous portion of the temporal bone to end at the fundus, where a thin plate of bone separates it from the vestibule; it gives passage to the facial and vestibulocochlear nerves together with the labyrinthine artery and veins" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004287 abnormal spiral limbus morphology "any structural abnormality in the border of the spiral lamina, i.e. the thickened periosteum covering the upper plate of the bony spiral lamina of the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004289 abnormal bony labyrinth "any structural abnormality in the series of cavities (cochlea, vestibule, and semicircular canals) contained within the otic capsule of the petrous portion of the temporal bone; the bony labyrinth is filled with perilymph, in which the delicate, endolymph-filled membranous labyrinth is suspended" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004290 abnormal stapes footplate "any structural abnormality in the flat portion of the stapes that fits in the oval window" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004292 abnormal spiral ligament fibrocyte morphology "any structural abnormality in the four types of fibrocytes (types I, II , III and IV) that constitute the spiral ligament" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Pou3f4Slf/Y
Genetic Background: C3H101H-Pou3f4Slf

Allelic Composition: Pou3f4Slf/Pou3f4Slf
Genetic Background: C3H101H-Pou3f4Slf

Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004293 abnormal type I spiral ligament fibrocytes "any structural abnormality of type I spiral ligament fibrocytes which occupy the region beneath the stria vascularis" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Tno/Y
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004294 abnormal type II spiral ligament fibrocytes "any structural abnormality of type II spiral ligament fibrocytes found in the suprastrial zone and the central area of the spiral ligament beneath the spiral prominence" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Tno/Y
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004404 cochlear outer hair cell degeneration "degeneration or loss of the columnar outer hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0004411 decreased endocochlear potential "reduction of the electrical potential difference between the endolymphatic and perilymphatic compartments of the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Pou3f4tm1Tno/Y
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0004479 abnormal oval window morphology "any structural anomlay in the oval opening on the medial wall of the tympanic cavity leading into the vestibule, close to the foot of the stapes" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004739 conductive hearing loss "progressive hearing loss due to lesions in the external auditory canal or middle ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004740 sensorineural hearing loss "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0004742 abnormal vestibular system physiology "any functional anomaly of the sensory system responsible for the sense of head position and movement of the body through space; such anomalies may include impaired balance, dizziness, poor regulation of postural muscle tone and inability to detect quick movements of the head " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0004813 absent linear vestibular evoked potential "absence of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cebpbtm1Kish/Cebpbtm1Kish,Cebpdtm1Aki/Cebpdtm1Aki
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Pou3f4del-J/Pou3f4del-J
Genetic Background: C3HeB/FeJ-Pou3f4del-J/J

Allelic Composition: Pou3f4del-J/Pou3f4+
Genetic Background: C3HeB/FeJ-Pou3f4del-J/J

 MP:0004862 small scala tympani "volume reduction of the division of the spiral canal of the cochlea lying on the basal side of the spiral lamina " [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005107 abnormal stapes morphology "structural anomaly of the smallest and innermost of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005272 abnormal temporal bone morphology "anomalous structure of the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005307 head tossing "compulsive flailing of the head in multiple directions" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0005627 increased circulating potassium level "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
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Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0006012 dilated endolymphatic duct "an expansion in the volume of the endolymphatic duct" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:67072:]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0006021 abnormal Reissner membrane morphology "any strutural alteration in Reissner s membrane which separates the cochlear duct from the vestibular canal, i.e. the endolymph of the scala media from the perilymph of the scala vestibuli; the Reissner membrane consists of squamous epithelial cells with microvilli toward the ductus, a basement membrane, and a thin layer of connective tissue toward the scala. " [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0006023 detached Reissner membrane "partial or complete loss of connection between the membrane and the vestibular wall" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0006025 distended Reissner membrane "an increase in the volume of endolymphatic fluid that results in distortion of the vestibular membrane" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0006325 impaired hearing "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Cebpbtm1Kish/Cebpbtm1Kish,Cebpdtm1Aki/Cebpdtm1Aki
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Pou3f4del-J/Pou3f4del-J
Genetic Background: C3HeB/FeJ-Pou3f4del-J/J

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0006359 absent startle reflex "failure to respond to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Pou3f4tm1Tno/Y
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4tm1Tno
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4tm1Tno/Pou3f4+
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Pou3f4sdl/Pou3f4sdl
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0030407 abnormal stapes crus morpholgy "any structural anomaly of either of the two (anterior and posterior) limbs of the stapes that pass from the head to the base or footplate; in mice, the anterior crus is curved and the posterior crus is more straight whereas in humans, the anterior crus is more straight than the posterior crus" [https://medical-dictionary.thefreedictionary.com/anterior+crus+of+stapes, PMID:28117786]
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Allelic Composition: Pou3f4tm1Cren/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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