| MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Sox4tm2Cle/Sox4tm2Cle
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0000138 | absent vertebrae | "missing bony segments of the spinal column" [J:35802] |
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Allelic Composition: Tc/T+
Genetic Background: mixed
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0000141 | abnormal vertebral body morphology | "malformed main portion of the vertebra anterior to the vertebral canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
|
| MP:0000154 | rib fusion | "appearance of one or more ribs as a single structure" [J:62022, J:62023] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
|
| MP:0000269 | abnormal looping morphogenesis | "atypical bending of the primitive heart tube during early development" [J:27443] |
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Allelic Composition: T/t6
Genetic Background: Not Specified
|
| MP:0000270 | abnormal heart tube morphology | "malformed embryonic heart " [J:37888] |
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Allelic Composition: T/t6
Genetic Background: Not Specified
|
| MP:0000292 | distended pericardial sacs | "stretched outer parietal layer of the pericardium" [J:25248] |
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Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
|
| MP:0000461 | reduced number of presacral vertebrae | "redecued number of the vertebrae anterior to the sacrum" [J:13069] |
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Allelic Composition: T/T+
Genetic Background: Not Specified
Allelic Composition: Tc/T+
Genetic Background: Not Specified
|
| MP:0000495 | abnormal colon morphology | "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
|
| MP:0000539 | distended urinary bladder | "stretched musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
|
| MP:0000585 | kinked tail | "a sharp bend or zig-zag in the tail" [J:61295] |
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Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
Allelic Composition: T11J/T+
Genetic Background: C57BL/6J-T11J/GrsrJ
|
| MP:0000592 | short tail | "reduced length of tail compared to control " [J:55583] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Sp5tm1Rbe/Sp5tm1Rbe,T/T+
Genetic Background: involves: 129P2/Ola * C57BL/6J
Allelic Composition: T40H/T+
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: T41H/T+
Genetic Background: involves: 101/Rl * BALB/cOlaHsd * C3H/Rl
Allelic Composition: T8J/T+
Genetic Background: C57BL/6J-Apoetm1Unc
Allelic Composition: T9J/T+
Genetic Background: C57BL/6J-T9J
Allelic Composition: T/T+
Genetic Background: Not Specified
Allelic Composition: T7J/T+
Genetic Background: C57BL/6J-T7J
Allelic Composition: T36H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T34H/T+
Genetic Background: involves: STOCK T34H * TFH
Allelic Composition: Tc/T+
Genetic Background: Not Specified
Allelic Composition: Tc/T+,Tg(T)118.9Bgh/0
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Th/T+
Genetic Background: Not Specified
Allelic Composition: TJic/T+
Genetic Background: Not Specified
Allelic Composition: T2J/T+
Genetic Background: C57BL/6J-T2J/J
Allelic Composition: T4J/T+
Genetic Background: BALB/cBy
Allelic Composition: T5J/T+
Genetic Background: C57BL/6J-T5J/J
Allelic Composition: TM1Shao/T+
Genetic Background: involves: C57BL/6J
Allelic Composition: T6J/T+
Genetic Background: involves: A/J * C57BL/6J
Allelic Composition: T11J/T+
Genetic Background: C57BL/6J-T11J/GrsrJ
Allelic Composition: T24H/T+
Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Ttm1(cre/ERT2)Hssk/T+
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
|
| MP:0000755 | hindlimb paralysis | "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
Allelic Composition: Tc/th7
Genetic Background: Not Specified
|
| MP:0000923 | abnormal roof plate morphology | "malformation or absence of a transient group of neuroepithelial cells located at the dorsal midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
|
| MP:0000929 | open neural tube | "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571] |
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Allelic Composition: T41H/T41H
Genetic Background: involves: 101/Rl * BALB/cOlaHsd * C3H/Rl
|
| MP:0000932 | absent notochord | "missing axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: T40H/T40H
Genetic Background: involves: C3H/HeH * C57BL/6J
Allelic Composition: T41H/T41H
Genetic Background: involves: 101/Rl * BALB/cOlaHsd * C3H/Rl
Allelic Composition: D17Aus9df12J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
Allelic Composition: D17Aus9df10J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
|
| MP:0000955 | abnormal spinal cord morphology | "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tc/T+
Genetic Background: mixed
Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0001216 | abnormal epidermal layer morphology | "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Ddb2tm1Vri/Ddb2+
Genetic Background: involves: 129P2/Ola * SKH1
Allelic Composition: D17Aus9df13J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
|
| MP:0001539 | decreased number of caudal vertebrae | "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Sp5tm1Rbe/Sp5tm1Rbe,T/T+
Genetic Background: involves: 129P2/Ola * C57BL/6J
Allelic Composition: T/T+
Genetic Background: Not Specified
|
| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Gngt1tm1Dgen/Gngt1tm1Dgen,Pdctm1Vya/Pdctm1Vya
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6
Allelic Composition: Th/Th
Genetic Background: Not Specified
|
| MP:0001684 | abnormal axial mesoderm | "malformed middle primary germ layer" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:51834] |
Show
Allelic Composition: TWis/TWis
Genetic Background: Not Specified
|
| MP:0001688 | abnormal somite development | "anomalous formation of any of the paired, metamerically arranged cell masses formed in the embryonic paraxial mesoderm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
|
| MP:0001689 | incomplete somite formation | "arrest of differentiation or patterning of the somites" [J:62882] |
Show
Allelic Composition: T41H/T41H
Genetic Background: involves: 101/Rl * BALB/cOlaHsd * C3H/Rl
|
| MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001701 | incomplete embryo turning | "arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571] |
Show
Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
|
| MP:0001712 | abnormal placental development | "malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001726 | abnormal allantois | "malformed fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622] |
Show
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
|
| MP:0001730 | embryonic growth arrest | "the cessation of development beyond a particular stage" [J:17509] |
Show
Allelic Composition: D17Aus9df13J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
Allelic Composition: D17Aus9df10J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
Allelic Composition: T1Or/T1Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T2Or/T2Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T3Or/T3Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T4Or/T4Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T5Or/T5Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T6Or/T6Or
Genetic Background: involves: 101 * C3H
|
| MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
Show
Allelic Composition: T36H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
|
| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
Show
Allelic Composition: Nox3het/Nox3het,T31H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T33H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T33H/T+,tw32/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T36H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
|
| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
Show
Allelic Composition: Nox3het/Nox3het,T31H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T30H/T+,tw32/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T22H/T+,tw32/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
|
| MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: TJic/T+
Genetic Background: Not Specified
|
| MP:0002080 | prenatal lethality | "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tc-2H/T+
Genetic Background: involves: 101/H * C3H/HeH
|
| MP:0002082 | postnatal lethality | "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tc/Tc
Genetic Background: mixed
Allelic Composition: Tc/T+
Genetic Background: Not Specified
Allelic Composition: Tc/th7
Genetic Background: Not Specified
|
| MP:0002111 | abnormal tail morphology | "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Scarb1tm1Kri/Scarb1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Tc/T+
Genetic Background: Not Specified
Allelic Composition: Tc/T+,Tg(T)118.9Bgh/Tg(T)118.9Bgh
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Tc/th51,Tg(T)118.9Bgh/0
Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: T/t4
Genetic Background: Not Specified
Allelic Composition: T/tAE5
Genetic Background: Not Specified
Allelic Composition: Tc-2H/T+
Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Ttm1(cre/ERT2)Hssk/T+
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
|
| MP:0002151 | abnormal neural tube morphology/development | "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Tc/T+
Genetic Background: mixed
Allelic Composition: Tc/Tc
Genetic Background: mixed
Allelic Composition: T/T+
Genetic Background: Not Specified
Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified
|
| MP:0002230 | abnormal primitive streak formation | "anomaly in the establishment of the midline ridge of embryonic epiblast that later develops into mesoderm and endoderm" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: TWis/TWis
Genetic Background: Not Specified
|
| MP:0002632 | vestigial tail | "a trace or rudimentary tail structure; the degenerated remains of any tail structure" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Tc-2H/T+
Genetic Background: involves: 101/H * C3H/HeH
|
| MP:0002825 | abnormal notochord | "malformation or absence of the axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: TWis/TWis
Genetic Background: Not Specified
Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
Allelic Composition: T/T+
Genetic Background: Not Specified
Allelic Composition: T/t6
Genetic Background: Not Specified
Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0002861 | abnormal tail bud morphology | "anomalous formation of the primordial region of the embryo that arises to form the tail of the adult; appears approximately ten days following conception as a short stump, and then initiates elongation and thinning in normal development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tc/T+
Genetic Background: mixed
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0003047 | abnormal thoracic vertebrae morphology | "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0003048 | abnormal cervical vertebrae morphology | "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Tc/T+
Genetic Background: Not Specified
|
| MP:0003049 | abnormal lumbar vertebrae morphology | "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Sp5tm1Rbe/Sp5tm1Rbe,T/T+
Genetic Background: involves: 129P2/Ola * C57BL/6J
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0003051 | curly tail | "a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: TM1Shao/T+
Genetic Background: involves: C57BL/6J
Allelic Composition: Ttm1(cre/ERT2)Hssk/T+
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
|
| MP:0003054 | spina bifida | "common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
Show
Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
|
| MP:0003087 | absent allantois | "missing fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: TWis/TWis
Genetic Background: Not Specified
|
| MP:0003400 | kinked neural tube | "twists or kinks in the embryonic neural tube" [J:66514, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
|
| MP:0003456 | absent tail | "completely lacking the appendage at the caudal end of the vertebral column " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: T41H/T41H
Genetic Background: involves: 101/Rl * BALB/cOlaHsd * C3H/Rl
Allelic Composition: Tc/T+
Genetic Background: Not Specified
Allelic Composition: TWis/T+
Genetic Background: involves: A/J
Allelic Composition: Th/t13
Genetic Background: Not Specified
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
Allelic Composition: T/tks1
Genetic Background: Not Specified
Allelic Composition: T/twN27
Genetic Background: Not Specified
Allelic Composition: T/t4
Genetic Background: Not Specified
Allelic Composition: T/tAE5
Genetic Background: Not Specified
Allelic Composition: Tc-2H/T+
Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: T/tbtm
Genetic Background: MOL-NIS
Allelic Composition: T/twPas1
Genetic Background: involves: BTBR/Nev T * M. m. brevirostris
Allelic Composition: T/twPas2
Genetic Background: involves: M. m. brevirostris
Allelic Composition: T/twPas3
Genetic Background: involves: M. m. domesticus
Allelic Composition: T4J/t6
Genetic Background: involves: BALB/cBy
Allelic Composition: T5J/t6
Genetic Background: involves: C57BL/6J
Allelic Composition: T t+/T+ th45
Genetic Background: Not Specified
Allelic Composition: T th20/T+ t+
Genetic Background: Not Specified
Allelic Composition: T/tw73
Genetic Background: involves: M. m. musculus
Allelic Composition: T26H/T+
Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: T/T+,th7m/t+
Genetic Background: Not Specified
Allelic Composition: T/T+,th7m2/t+
Genetic Background: Not Specified
Allelic Composition: T/T+,thr1/t+
Genetic Background: Not Specified
Allelic Composition: T/T+,thr15/t+
Genetic Background: Not Specified
Allelic Composition: T/T+,thr4/t+
Genetic Background: Not Specified
Allelic Composition: T24H/T+,th2/t+
Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Ttm1(cre/ERT2)Hssk/T+
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
Allelic Composition: T/tw3
Genetic Background: Not Specified
|
| MP:0003861 | abnormal nervous system development | "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
| MP:0003885 | abnormal rostro-caudal body axis extension | "anomaly in or failure of the long (rostral-caudal) axis of the body to elongate normally once patterning has been established" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
|
| MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
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| MP:0004073 | caudal body truncation | "caudal part of body truncated with anterior portion relatively normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Tc/Tc
Genetic Background: mixed
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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| MP:0004179 | transmission ratio distortion | "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: T33H/T+,tw32/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T32H/T+,th51/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T29H/T+,tw32/t+
Genetic Background: involves: BALB/c * TFH
Allelic Composition: T32H/T+,tw32/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T34H/T+,tw32/t+
Genetic Background: involves: 101/H * C3H/HeH * STOCK T34H * TFH
Allelic Composition: T29H/T+,t6/t+
Genetic Background: involves: BALB/c * TFH
Allelic Composition: T30H/T+,t6/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T32H/T+,t6/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T36H/T+,t6/t+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T/tks1
Genetic Background: Not Specified
Allelic Composition: T/t4
Genetic Background: Not Specified
Allelic Composition: T/twPas1
Genetic Background: involves: BTBR/Nev T * M. m. brevirostris
Allelic Composition: T/twPas2
Genetic Background: involves: M. m. brevirostris
Allelic Composition: T/twPas3
Genetic Background: involves: M. m. domesticus
Allelic Composition: T ts6/T+ t+
Genetic Background: Not Specified
Allelic Composition: T/tw73
Genetic Background: involves: M. m. musculus
Allelic Composition: Itpr3tf/Itpr3+,T/T+,thr4/t+
Genetic Background: involves: BTBR
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| MP:0004180 | failure of initiation of embryo turning | "failure to begin the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: D17Aus9df12J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
Allelic Composition: D17Aus9df10J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
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| MP:0004251 | failure of looping morphogenesis | "failure of the primitive heart tube to initiate or complete looping" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
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| MP:0004509 | abnormal pelvic girdle bone morphology | "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
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Allelic Composition: T11J/T+
Genetic Background: C57BL/6J-T11J/GrsrJ
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| MP:0004603 | absent vertebral arch | "loss of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
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| MP:0004607 | abnormal cervical atlas morphology | "any structural anomaly of the first (topmost, C1) cervical vertebra which supports the globe of the head" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0004609 | vertebral fusion | "the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0004613 | fusion of vertebral arches | "improper union of the dorsal part of adjacent vertebra" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0004620 | cervical vertebral fusion | "the union of one or more cervical vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0004623 | thoracic vertebral fusion | "the union of one or more thoracic vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0004653 | absent caudal vertebrae | "absence of all of the bony segments of the coccyx or tail; there are usually 27-30 present in rodents and only 3-5 fused vertebrae in human" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
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| MP:0004656 | absent sacral vertebrae | "absence of all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
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| MP:0004659 | abnormal odontoid process | "any structural anomaly of the large protuberance that projects upward from the cervical axis, around which the cervical atlas rotates" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A02.835.232.834.151.383.668] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0004668 | absent vertebral body | "absence of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
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| MP:0004672 | short ribs | "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0004712 | notochord degeneration | "retrogressive pathologic change of the axial fibrocellular cord in embryos around which develops the vertebral primordia (prior to normal differentiation of this tissue into the vertebral column tissues)" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
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| MP:0004713 | split notochord | "the appearance of an abnormal division in the axial fibrocellular cord in embryos around which develops the vertebral primordia" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Tc/T+
Genetic Background: mixed
Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
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| MP:0004787 | abnormal dorsal aorta morphology | "any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0004837 | abnormal neural fold formation | "any anomaly in the process by which the edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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| MP:0005191 | head tilt | "condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Nox3het/Nox3het,T31H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: Nox3het/Nox3het,T33H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: Nox3het/Nox3het,T36H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
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| MP:0005226 | abnormal vertebral arch development | "anomalous formation of the posterior projection from the body of a vertebra that encloses the vertebral foramen " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0005227 | abnormal vertebral body development | "anomalous formation of the main portion of the vertebra anterior to the vertebral canal, and distinct from the vertebral arch" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Tc/Tc,tw5/tw5
Genetic Background: mixed
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| MP:0005244 | hemopericardium | "bleeding into the pericardial space" [Pathology:ISBN 0-397-51047-0] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0005297 | spina bifida occulta | "common congenital midline defect of fusion of the vertebral arch without protrusion of the spinal cord or meninges" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Tc/T+
Genetic Background: mixed
Allelic Composition: Tc/th7
Genetic Background: Not Specified
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| MP:0005650 | abnormal limb bud morphology | "aberrant structure or development of any of the swellings on the trunk of the embryo that become limbs" [hdene:Howard Dene , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:61460] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Tc/Tc
Genetic Background: mixed
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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| MP:0006281 | abnormal tail development | "anomaly in the formation of the tail" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
Allelic Composition: T11J/T+
Genetic Background: C57BL/6J-T11J/GrsrJ
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| MP:0006386 | absent somites | "missing all somites" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/Tc
Genetic Background: mixed
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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| MP:0006392 | abnormal nucleus pulposus morphology | "any anomaly in the structure or formation of the jelly-like substance in the middle of the spinal disc which is a remnant of the notochord" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0008762 | embryonic lethality | "death of an animal in the embryonic period (Mus: up to E14)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: H1f0tm1Ais/H1f0tm1Ais,Hist1h1dtm1Ais/Hist1h1dtm1Ais
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: T/tbtm
Genetic Background: MOL-NIS
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| MP:0008854 | bleb | "presence of a blister-like, nearly hemispherical structure formed during embryonic development filled with air, serous fluid or blood" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0008999 | absent anus | "absence of the lower opening of the digestive tract" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: T11J/T+
Genetic Background: C57BL/6J-T11J/GrsrJ
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| MP:0009929 | meningomyelocele | "hernial protrusion of the spinal cord and its meninges through an opening or defect in the vertebral column" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: T29H/T+
Genetic Background: involves: BALB/c * TFH
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| MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Tc/T+
Genetic Background: Not Specified
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| MP:0011090 | partial perinatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Nox3het/Nox3het,T31H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T33H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T36H/T+
Genetic Background: involves: 101/H * C3H/HeH * TFH
Allelic Composition: T34H/T+
Genetic Background: involves: STOCK T34H * TFH
Allelic Composition: T29H/T+
Genetic Background: involves: BALB/c * TFH
Allelic Composition: T/tbtm
Genetic Background: MOL-NIS
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| MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Sox18Ra/Sox18+
Genetic Background: Not Specified
Allelic Composition: T9J/T9J
Genetic Background: C57BL/6J-T9J
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| MP:0011092 | complete embryonic lethality | "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: T41H/T41H
Genetic Background: involves: 101/Rl * BALB/cOlaHsd * C3H/Rl
Allelic Composition: Th/Th
Genetic Background: Not Specified
Allelic Composition: Ttm1(cre/ERT2)Hssk/Ttm1(cre/ERT2)Hssk
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
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| MP:0011096 | complete embryonic lethality before somite formation | "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith] |
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Allelic Composition: T7J/T+
Genetic Background: C57BL/6J-T7J
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| MP:0011097 | complete embryonic lethality before turning of embryo | "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith] |
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Allelic Composition: TWis/TWis
Genetic Background: Not Specified
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| MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Tc/Tc
Genetic Background: mixed
Allelic Composition: TTg(MT2A-Myc)137Misu/TTg(MT2A-Myc)137Misu
Genetic Background: C57BL/6-TTg(MT2A-Myc)137Misu
Allelic Composition: D17Aus9df12J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
Allelic Composition: D17Aus9df10J/T7J
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6
Allelic Composition: T1Or/T1Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T2Or/T2Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T3Or/T3Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T4Or/T4Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T5Or/T5Or
Genetic Background: involves: 101 * C3H
Allelic Composition: T6Or/T6Or
Genetic Background: involves: 101 * C3H
Allelic Composition: Tc/T
Genetic Background: Not Specified
Allelic Composition: TM1Shao/TM1Shao
Genetic Background: involves: C57BL/6J
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| MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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| MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Tc-2H/T+
Genetic Background: involves: 101/H * C3H/HeH
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| MP:0011495 | abnormal head shape | "any anomaly in the characteristic surface outline or contour of a head of an organism" [MGI:csmith] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0012063 | absent tail bud | "missing the primordial region of the embryo that arises to form the tail of the adult" [MGI:anna] |
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Allelic Composition: Tc/Tc
Genetic Background: mixed
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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| MP:0012082 | delayed heart development | "late onset of the induction and/or differentiation of the heart" [MGI:anna] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0012501 | abnormal pericardial cavity morphology | "any structural anomaly of the anatomical body cavity in which the heart lies; the pericardial cavity forms in the lateral plate mesoderm above the buccopharyngeal membrane, as part of the early intraembryonic coelom, and is initially continuous with the two early pleural cavities" [MGI:anna] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0012714 | decreased ventral ectodermal ridge size | "reduced size of the morphologically distinct group of ectodermal cells that serves as an important signaling center in the mouse tail-bud following completion of gastrulation, and contains progenitor cells that contribute to the ventral midline ectoderm of the tail" [MGI:anna] |
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Allelic Composition: T/T+
Genetic Background: Not Specified
Allelic Composition: T/t6
Genetic Background: Not Specified
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| MP:0013164 | abnormal forelimb bud morphology | "any structural anomaly of the limb bud that develops into a forelimb (usually the arm or front limb in mammalian species)" [MGI:anna] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0013165 | absent forelimb buds | "absence or loss of the limb bud that normally develops into a forelimb (usually the arm or front limb in mammalian species)" [MGI:anna] |
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Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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| MP:0013168 | absent hindlimb buds | "absence or loss of the limb bud that normally develops into a hindlimb (usually the leg or back limb in mammalian species)" [MGI:anna] |
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Allelic Composition: Foxc2tm1Miu/Foxc2tm1Miu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Tc/Tc
Genetic Background: Not Specified
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